Critiquing: Dr. David H. “Orac” Gorski, M.D., Ph.D, L.I.A.R.

L.I.A.R.

Lacking
Integrity
And
Respect

Respect is EARNED

Dr. David H. “Orac” Gorski has NOT earned respect

Neither does he deserve it

6/4/2013 Gorski made an amazing admission:
======================================

http://scienceblogs.com/insolence/2013/06/04/stanislaw-burzynski-versus-the-bbc/

======================================
“Dr. Elloise Garside, a research scientists, echoes a lot of the questions I have, such as”

“how Burzynski never explains which genes are targeted by antineoplastons … “
——————————————————————
Gorski has claimed:
======================================
6/7/2013 “Unlike Mr. Merola, I am indeed very concerned with getting my facts correct”
——————————————————————

http://scienceblogs.com/insolence/2013/06/07/i-want-my-anp/

======================================
6/5/2013 “ … I do know cancer science”
——————————————————————

http://scienceblogs.com/insolence/2013/06/05/odds-and-ends-about-burzynski-clinic/

======================================
11/2/2012 “Personally, having pored over Burzynski’s publications … “
——————————————————————

http://scienceblogs.com/insolence/2012/11/02/stanislaw-burzynski-fails-to-save-another-patient/

======================================
5/8/2013 “I’ve searched Burzynski’s publications … “
——————————————————————

http://scienceblogs.com/insolence/2013/05/08/eric-merola-and-stanislaw-burzynskis-secret-weapon-against-the-skeptics-fabio-lanzoni-part-2/

======================================
7/22/2013 I published the below article on my blog:
======================================
Critiquing: In which Orac does Stanislaw Burzynski propagandist Eric Merola a favor…:
——————————————————————

https://stanislawrajmundburzynski.wordpress.com/2013/07/22/critiquing-in-which-orac-does-stanislaw-burzynski-propagandist-eric-merola-a-favor/

======================================
“… because Gorski and others do NOT seem to understand how antineoplastons (ANP) A10 (Atengenal) and AS2-1 (Astugenal) work, I provide the relevant Burzynski publications and page #’s for them to review:
——————————————————————
Gorski, here’s

” … how Burzynski never explains which genes are targeted by antineoplastons … “
======================================
[1] Pg. 98
——————————————————————
ras oncogenes
tumor suppressor gene p53
ras oncogene protein p21ras
p21 gene

======================================
[2] Pg. 47
——————————————————————
oncogenes
tumor suppressor genes

——————————————————————
Pg. 48
——————————————————————
gene p53
WRN gene

——————————————————————
Mechanism of Action of Antineoplaston
——————————————————————
tumor suppressor genes
oncogenes
p21 protein
p53 gene

——————————————————————
Pg. 49
——————————————————————
tumor suppressor gene p53
tumor suppressor gene p21

======================================
[3] Pg. 257
——————————————————————
tumor suppressor genes
oncogenes

——————————————————————
Pg. 260 Discussion
——————————————————————
oncogene AKT2
oncogene RAS
oncogene MYCC
tumor suppressor p53
tumor suppressor p21
tumor suppressor PTEN
tumor suppressor INI1

======================================
[4] Pg. 385
——————————————————————
AKT2 pathway
TGFB1 pathway
RAS
TP53
p21

======================================
[5] Pg. 386
——————————————————————
RAS pathway
AKT2 pathway
TGFB1 pathway
p53 tumor suppressor gene
p21 tumor suppressor gene

======================================
[6] Pg. 323 Discussion
——————————————————————
TP53 gene
——————————————————————
Pgs. 323-324
——————————————————————
RAS oncogene
TP53 tumor suppressor gene
p21 tumor suppressor gene
NF1 tumor suppressor gene
p21 RAS protein
RNAi
dsRNA
siRNA
RAS oncogene pathway (GF-RTK-RAS)
oncogenes
oncogene AKT2

======================================
[7] Pg. 173 Discussion
——————————————————————
proto-oncogene MYCC, ERBB2
——————————————————————
Pg. 174
——————————————————————
sonic hedgehog (SHH) receptor patched (PTCH)
MYCC
MYC-MAX dimers
G1-S
gene CCD2 (encoding cyclin D2)
gene CDK4 (which encodes cyclin dependent kinase 4)
KIP1
(or p27)
CUL-1
CKS
MYC
cyclin E-CDK2
INK4B
(or p15)
p21
cyclin E/CDK2
MIZ1 (MYC-interacting zinc finger protein 1)
CDKN1A
CDKN2B
MAD protein
MEFD2D (MADS box transcription enhancer factor
17p
tumor-suppressor gene HIC-1 (hypermethylated in cancer-1)
RAS/MAPK
RAS pathway
RAS protein
AKT2
BCL2
BCL-X
BAX

——————————————————————
Pgs. 175-176 Charts
======================================
[8] Pg. 40
——————————————————————
RAS
AKT
TP53
PTEN
INI1
p21
MYCC
apoptosis pathway
DNA
p21 protein
RAS oncogene
INI1 protein
BCL-X

——————————————————————
Pg. 41 Targeted Therapy with Antineoplastons chart
——————————————————————
protein p21
RAS oncogene
RAS
BCL-2
tumor suppressor gene TP53
tumor suppressor gene p21
DNA
oncogene AKT2
oncogene MYCC
tumor suppressor gene PTEN
tumor suppressor gene MAD
INI1 protein
BCL-X protein

——————————————————————
Pg. 46 Discussion / Conclusion
——————————————————————
AKT/PTEN
RAS
p53
p21
MYCC
apoptosis pathways

======================================
[9] Pg. 384 E. Multitargeted therapy
——————————————————————
RAS pathway
AKT2 pathway
TP53 pathway
PTEN
INI1
p21 pathway
MYCC
apoptosis pathways
TGFB1 pathway
MAD

======================================
[10] Pg. 1068
——————————————————————
AKT2 pathway
MYCC pathway
TGFB1
PTEN tumor suppressor gene
MAD tumor suppressor gene
RANBP1
INI protein
RAS pathway
BCL2 pathway
tumor suppressor TP53
tumor suppressor p21

======================================
[11] Pg. 923
——————————————————————
AKT pathway
RAS pathway
TP53 pathway
p21 pathway
PTEN pathway

======================================
Burzynski, Hideaki Tsuda (Japan), and the p53 gene:
——————————————————————

https://stanislawrajmundburzynski.wordpress.com/2013/03/04/burzynski-hitoshi-tsuda-japan-and-the-p53-gene/

� � � � � � � � � � � � � � � �
References:
� � � � � � � � � � � � � � � �

http://www.burzynskiclinic.com/scientific-publications.html

======================================
[1] 2003
——————————————————————
Interim Reports on Clinial Trials
16. 2003 (BT-11)
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report
DRUGS IN R&D
——————————————————————

http://www.ncbi.nlm.nih.gov/pubmed/12718563

——————————————————————
Drugs in R and D
——————————————————————

http://www.ncbi.nlm.nih.gov/m/pubmed/12718563

——————————————————————
(Drugs in Research and Development)
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/960.pdf

——————————————————————
Drugs R D. 2003;4(2):91-101
Drugs in R&D 2003;4:91-101
======================================
[2] 3/2004
——————————————————————
Review Articles on Clinical Trials:
1. 3/2004
The Present State of Antineoplaston Research
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/994.pdf

——————————————————————
Integrative Cancer Therapies 2004;3:47-58
Volume 3, No. 1, March 2004
DOI: 10.1177/1534735-403261964
Volume 3 Number 1 March 2004
======================================
[3] 9/2004
——————————————————————
Case Reports:
4. 9/2004 (Special Exception (SE) to BT-11 Study (ST))
Long-term survival and complete response of a patient with recurrent diffuse intrinsic brain stem glioblastoma multiforme
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/1145.pdf

——————————————————————
Integrative Cancer Therapies 2004;3:257-261
Volume 3, Number 3 September 2004
DOI: 10.1177/1534735404267748
======================================
[4] 10/2004
——————————————————————
Interim Reports on Clinial Trials:
2. 10/2004
Phase II study of Antineoplastons A10 and AS2-1 (ANP) in recurrent glioblastoma multiforme
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/1218.pdf

——————————————————————
Neuro-Oncology. 2004; 6: 384
Volume 6 Issue 4 October 2004
Abstracts from the Society for Neuro-Oncology Ninth Annual Meeting, Toronto, Ontario, Canada, November 18-21, 2004
======================================
[5] 10/2004
——————————————————————
Interim Reports on Clinial Trials:
3. 10/2004 (Study (ST) and Special Exception (SE))
Long-term survivals in phase II studies of Antineoplastons A10 and AS2-1 (ANP) in patients with diffuse intrinsic brain stem glioma
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/1219.pdf

——————————————————————
Neuro-Oncology. 2004; 6: 386
Volume 6 Issue 4 October 2004
======================================
[6] 2004
——————————————————————
Interim Reports on Clinial Trials:
17. 2004 (BT-13 and BT-23)
Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma :
a preliminary report
DRUGS IN R&D
——————————————————————

http://www.ncbi.nlm.nih.gov/pubmed/15563234

——————————————————————
Drugs in R and D
——————————————————————

http://www.ncbi.nlm.nih.gov/m/pubmed/15563234

——————————————————————
(Drugs in Research and Development)
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/1194.pdf

——————————————————————
Drugs R D. 2004;5(6):315-26
Drugs R&D 2004;5(6):315-326.
======================================
[7] 6/2005
——————————————————————
Interim Reports on Clinial Trials:
18. 6/2005 (CAN-01 and BT-12)
Burzynski, S.R., Weaver, R.A., Janicki, T., Szymkowski, B., Jurida, G., Khan, M., Dolgopolov, V.
Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with Antineoplastons A10 and AS2-1
——————————————————————

http://www.ncbi.nlm.nih.gov/pubmed/15911929

——————————————————————
Integr Cancer Ther. 2005 Jun;4(2):168-77
——————————————————————

http://www.ncbi.nlm.nih.gov/m/pubmed/15911929

——————————————————————
Integrative Cancer Therapies 2005;4(2):168-177
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/1220.pdf

——————————————————————
DOI: 10.1177/1534735405276835
——————————————————————

http://m.ict.sagepub.com/content/4/2/168.long?view=long&pmid=15911929

——————————————————————
Volume 4 Number 2 June 2005
======================================
[8] 3/2006
——————————————————————
Interim Reports on Clinial Trials:
19. 3/2006 (BT-03, BT-11, BT-18, and CAN-01)
Targeted therapy with Antineoplastons A10 and AS2-1 of high grade, recurrent, and progressive brainstem glioma.
——————————————————————

http://www.ncbi.nlm.nih.gov/pubmed/16484713

——————————————————————
Integr Cancer Ther. 2006 Mar;5(1):40-7
——————————————————————

http://www.ncbi.nlm.nih.gov/m/pubmed/16484713

——————————————————————
Integrative Cancer Therapies 2006;5(1):40-47
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/5825.pdf

——————————————————————
DOI: 10.1177/1534735405285380
——————————————————————

http://m.ict.sagepub.com/content/5/1/40.long?view=long&pmid=16484713

======================================
[9] 12/2007
——————————————————————
Review Articles on Clinical Trials:
3. 12/2007
Recent clinical trials in diffuse intrinsic brainstem glioma. Cancer Therapy 2007; 5, 379-390.
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/5692.pdf

——————————————————————
Review Article
Cancer Therapy Vol 5, 379-390, 2007
——————————————————————

http://www.cancer-therapy.org/CT/v5/B/HTML/42._Burzynski,_379-390.html

——————————————————————
Volume 5 Number 2 December, 2007
======================================
[10] 12/2008
——————————————————————
Interim Reports on Clinical Trials:
12. 12/2008
(BT-8 – PATIENTS WITH ANAPLASTIC ASTROCYTOMA)
(BT-15 – ADULT PATIENTS WITH ANAPLASTIC ASTROCYTOMA)
Phase II study of antineoplastons A10 and AS2-1 infusions (ANP) in patients with recurrent anaplastic astrocytoma
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/7898.pdf

——————————————————————
Neuro-Oncology 2008; 10:1067
Volume 10 Issue 6 December 2008
Abstracts for the Eighth Congress of the European Association for Neuro-Oncology (EANO), Sept. 12-14, 2008, Barcelona, Spain
======================================
[11] 12/2009
——————————————————————
Case Reports:
1. 12/2009 (BT-11 Special Exception (SE))
Over a 10-year survival and complete response of a patient with diffuse intrinsic brainstem glioma (DBSG) treated with antineoplastons (ANP).
——————————————————————

http://www.burzynskiclinic.com/images/stories/Publications/8638.pdf

——————————————————————
Neuro-Oncology 2009; 11:923.
Volume 11 Issue 6 December 2009
Abstracts from the Third Quadrennial Meeting of the World Federation of Neuro-Oncology (WFNO) and the Sixth Meeting of the Asian Society for Neuro-Oncology (ASNO), May 11-14, 2009, Yokohama, Japan
======================================

About these ads

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s