Critiquing Bob Blaskiewicz (#Burzynski Cancer is Serious Business, Part II) @rjblaskiewicz
rjblaskiewicz:
Except YOU do NOT actually believe in
“interesting and civil discussions,”
do you, Bobby ?
rjblaskiewicz:
Bobby, please point out where the Declaration of Helsinki supports your tweet
http://www.wma.net/en/30publications/10policies/b3
Please point out where the National Cancer Institute (NCI) at the National Institutes of Health (NIH) supports your tweet
http://m.cancer.gov/topics/factsheets/clinical-trials
rjblaskiewicz
rjblaskiewicz:
Do you mean THIS present ?
“Let’s make Houston cancer quack Burzynski pay!”
PZ Myers
“there is a plan to remind him of the grief he has caused”
“his snake oil”
“bilk people out of buckets of money”
“Crime does pay”
“This fraud”
“The Burzynski clinic is a place you go to die”
“The lies”
“his quackery”
Do you mean THIS St. Jude ?
St. Jude:
http://www.stjude.org/stjude/v/index.jsp?vgnextoid=403c6f9523e70110VgnVCM1000001e0215acRCRD
2/15/2012 – the U.S. Department of Health and Human Services has awarded St. Jude Children’s Research Hospital $4,314,800 for a childhood cancer survivor study
The new federal funds will be distributed by the National Cancer Institute (NCI)
http://cohen.house.gov/press-release/cohen-st-jude-receive-43-million-childhood-cancer-survivor-study
Tax-Exempt
Receives Federal Grants / Funds
http://www.stjude.org/stjude/v/index.jsp?vgnextoid=b7e79bb8a0cf5110VgnVCM1000001e0215acRCRD&cpsextcurrchannel=1
Donations to St. Jude are tax deductible as allowed by law
http://www.stjude.org/stjude/v/index.jsp?vgnextoid=6f8afa3186e70110VgnVCM1000001e0215acRCRD&vgnextchannel=2f62940504f9a210VgnVCM1000001e0215acRCRD
FORBES: St. Jude CEO – $742,718
http://www.forbes.com/fdc/welcome_mjx.shtml
Burzynski does NOT receive Federal Funds
Burzynski does NOT receive Federal Grants
Burzynski is NOT Tax-Exempt
Burzynski donations can NOT be deducted from a U.S. Tax Return
rjblaskiewicz:
THIS Phenylbutyrate (PB) ?
Phenylacetylglutaminate (PG) and Phenylacetate (PN) are metabolites of PHENYLBUTYRATE (PB) and are constituents of antineoplaston AS2-1
SODIUM PHENYLBUTYRATE was given an orphan drug designation by the FDA for use as an adjunct to
surgery,
radiation therapy, and
chemotherapy
for treatment of individuals with
primary or recurrent malignant glioma
Cumulative List of all Products that have received Orphan Designation: Total active designations: 2002 Effective: 5/5/2009
http://www.fda.gov/downloads/forindustry/developingproductsforrarediseasesconditions/howtoapplyfororphanproductdesignation/ucm162066.xls
PHENYLBUTYRATE and SODIUM PHENYLBUTYRATE are listed alphabetically in the lower 1/4th of this document
Pubmed 110 entries
Sodium Phenylbutyrate
“Sodium Phenylbutrate (aka PB) …”
Sodium Phenylbutyrate (PB)
Year – Pubmed (110 entries)
1958 1st entry
1995 1st clinical trial
2001 Phase 1
2009 Phase 2
2012 Phase 3
rjblaskiewicz:
THESE trials ?
2003 – 2006 Phase II preliminary reports
2003 – Phase II
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma:
a preliminary report
http://www.ncbi.nlm.nih.gov/m/pubmed/12718563
Drugs R D. 2003;4(2):91-101
recurrent diffuse intrinsic brain stem glioma
antineoplaston A10 and AS2-1
6 months median duration of treatment
of all 12 patients
2 years / 33.3% – Survival
2 / 17% – alive and tumour free for over 5 years since initial diagnosis
from the start of treatment
5 years – 1 alive for more than
4 years – 1 alive for more than
Only mild and moderate toxicities were observed, which included
3 cases of skin allergy
2 cases of:
anaemia
fever
hypernatraemuia
single cases of:
agranulocytosis
hypoglycaemia
numbness
tiredness
myalgia
vomiting
2003 – Protocol – recurrent diffuse intrinsic brain stem glioma
12 – Patients Accrued
10 – Evaluable Patients
2 / 20% – # and % of Patients Showing Complete Response
3 / 30% – # and % of Patients Showing Partial Response
3 / 30% – # and % of Patients Showing Stable Disease
2 / 20% – # and % of Patients Showing Progressive Disease
2004 – Phase II
Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma :
a preliminary report
http://www.ncbi.nlm.nih.gov/m/pubmed/15563234
Drugs R D. 2004;5(6):315-26
incurable recurrent and progressive multicentric glioma
antineoplaston A10 and AS2-1 (ANP)
9 – patients’ median age
6 patients were diagnosed with pilocytic astrocytoma
4 with low-grade astrocytoma
1 with astrocytoma grade 2
1 case of visual pathway glioma, a biopsy was not performed due to a dangerous location
16 months – The average duration of intravenous ANP therapy
19 months – The average duration of oral ANP
1 patient was non-evaluable due to only 4 weeks of ANP and lack of follow-up scans
1 patient who had stable disease discontinued ANP against medical advice and died 4.5 years later
10 patients are alive and well from 2 to >14 years post-diagnosis
Only 1 case of serious toxicity of reversible tinnitus, of 1 day’s duration, was described
2004 – Protocol – incurable recurrent and progressive multicentric glioma
12 – Patients Accrued
33% – % of Patients Showing Complete Response
25% – % of Patients Showing Partial Response
33% – % of Patients Showing Stable Disease
0 / 0% – # and % of Patients Showing Progressive Disease
2005 – Phase II
Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1
http://www.ncbi.nlm.nih.gov/m/pubmed/15911929
Integr Cancer Ther. 2005 Jun;4(2):168-77
13 children with recurrent disease or high risk
6 (46%) survived more than 5 years
2005 – Protocol – recurrent disease or high risk
23% – % of Patients Showing Complete Response
8% – % of Patients Showing Partial Response
31% – % of Patients Showing Stable Disease
38% – % of Patients Showing Progressive Disease
2006 – Phase II
Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma
http://www.ncbi.nlm.nih.gov/m/pubmed/16484713
Integr Cancer Ther. 2006 Mar;5(1):40-7
Brainstem glioma carries the worst prognosis of all malignancies of the brain
Most patients with brainstem glioma fail standard radiation therapy and chemotherapy and do not survive longer than 2 years
Treatment is even more challenging when an inoperable tumor is of high-grade pathology (HBSG)
patients with inoperable tumor of high-grade pathology (HBSG) treated with antineoplastons in 4 phase 2 trials
39% – overall survival at 2 years
22% – overall survival at 5 years
17+ years maximum survival for a patient with anaplastic astrocytoma
5+ years for a patient with glioblastoma
39% – Progression-free survival at 6 months
5+ year survival in recurrent diffuse intrinsic glioblastomas and anaplastic astrocytomas of the brainstem in a small group of patients
18 – evaluable
4 – glioblastomas
14 – anaplastic HBSG
14 – diffuse intrinsic tumors
12 – recurrence
6 – did not have radiation therapy or chemotherapy
Antineoplastons, A10 (A10I) and AS2-1 injections
5 months median duration
Responses were assessed by gadolinium-enhanced magnetic resonance imaging and positron emission tomography
Antineoplastons tolerated very well
1 case of grade 4 toxicity (reversible anemia)
2006 – Protocol – high-grade pathology (HBSG)
18 – Evaluable Patients
11% – % of Patients Showing Complete Response
11% – % of Patients Showing Partial Response
39% – % of Patients Showing Stable Disease
39% – % of Patients Showing Progressive Disease
2/24/2013
http://www.skeptical.gb.net/blog/?p=1442
2/27/2013
http://www.skeptical.gb.net/blog/?p=1798
3/9/2013
http://www.thetwentyfirstfloor.com/?p=8001
rjblaskiewicz:
Bobby, oh REALLY ?
“The Skeptics” (Burzynski: Cancer is Serious Business, Part II)
The “group” “The Sketics” claims is NOT a “group” and which allegedly does NOT spread “misinformation”
https://stanislawrajmundburzynski.wordpress.com/2013/03/24/the-skeptics
rjblaskiewicz:
No Bobby, you did NOT
rjblaskiewicz:
“VAMPIRE” ?
rjblaskiewicz:
Bobby, like THIS ?
Stanislaw Rajmund Burzynski, M.D., Ph.D and “Freedom of Speech”
“The most stringent protection of free speech would not protect a man in falsely shouting ‘fire’ in a theater and causing a panic.”
United States Supreme Court ruled 3/3/1919
Schenck v. United States, 249 U.S. 47 (1919)
https://stanislawrajmundburzynski.wordpress.com/2013/03/24/stanislaw-rajmund-burzynski-m-d-ph-d-and-freedom-of-speech
rjblaskiewicz:
Bobby, like THIS ?
David H. Gorski and the Cult of “MISINFORMATION”
Colorado Public Television 12 – PBS: Part II
https://stanislawrajmundburzynski.wordpress.com/2013/03/10/david-h-gorski-and-the-cult-of-misinformation
Orac and the Cult of “Misinformation” (Part III)
David H. Gorski
https://stanislawrajmundburzynski.wordpress.com/2013/03/11/orac-and-the-cult-of-misinformation-part-iii
Josephine Jones and the Cult of Misinformation
JJ recently blogged:
https://stanislawrajmundburzynski.wordpress.com/2013/03/13/josephine-jones-and-the-cult-of-misinformation
Keir Liddle and the Cult of MISINFORMATION
https://stanislawrajmundburzynski.wordpress.com/2013/03/09/keir-liddle-and-the-cult-of-misinformation
The Cult of “Misinformation”
Review of “disinformation,” “misinformation,” and “misdirection” posted by #Burzynski critics
https://stanislawrajmundburzynski.wordpress.com/2013/03/11/the-cult-of-misinformation
The cult of “Misinformation” continued
Adam Jacobs
https://stanislawrajmundburzynski.wordpress.com/2013/03/12/the-cult-of-misinformation-continued
rjblaskiewicz:
Bobby, where’s your
Citation(s),
Reference(s), and / or
Link(s) ?
rjblaskiewicz:
Bobby, Adam Jacobs does NOT care about “FREE SPEECH,” he censors it:
http://dianthus.co.uk/burzynski-qa
rjblaskiewicz:
Well, Bobby
We know a lot of the skeptics seem to “hate” the truth
rjblaskiewicz:
Bobby, maybe you should have actually watched THIS:
Burzynski Infomercial on Colorado PBS 12
http://www.skeptical.gb.net/blog/?p=2401
rjblaskiewicz:
Bobby, maybe you should ACTUALLY listen to it
rjblaskiewicz:
Yeah, riiiiiiiiight, Bobby
rjblaskiewicz:
“Response to the release of Burzynski 2, Havanna Nights”
http://t.co/t9WMpNRN9L
Skeptical Humanities
Learning is Cool
Response to the release of Burzynski 2, Havanna Nights
Posted by Bob
On this week’s episode of the Virtual Skeptics, I replied to what was learned at the premiere of the new Burzynski movie
The text of my segment follows the episode
This week, the new Burzynski movie premiered in San Luis Obispo, California
We largely knew what was going to be in the movie since a couple of trailers had been released, the patients who appeared had talked about the filming, and there was a sort of credulous review had appeared a few days ahead of time and I believe the director may have mentioned it on a PBS fundraising specual a few days earlier
So we had a pretty good idea of what our proxies should be looking for
We really wanted to see if certain people who had been filmed, like Amelia Saunders or Hannah Bradley appeared and especially what was said about them
We wanted lists of people who appeared, to see if we might be able to put together who said what
Most of these people’s stories are well known, and we doubted there would be anything new
Also our people took down key quotes that struck them as important, like
(those notes did NOT seem very “key” considering Orac’s (David H. Gorski @gorskon #sciencebasedmedicine @ScienceBasedMed @oracknows) “Second-Hand” “review” of Burzynski: Cancer is Serious Business, Part II)
“skeptics are hiding behind their BS free speech.”
(Yep, TRUE)
This is my takeaway, after talking to the people who I know were there
We are wiggly little scumbags who are hateful and slimy
(some skeptics seem to be “hateful” of the truth)
We ridicule the desperate and dying
Some of us are paid by big pharma
Others are deluded and think that we are doing good but are being misled
(that is a fair description of “misinformation,” “disinformation,” and “misdirection”)
But make no mistake–and this was hammered home to me by everyone I talked to–we are to them pure evil
One of my big concerns going into the movie was how I was going to be portrayed and whether or not I was going to receive death threats
That my family was going to receive death threats or that I was going to be harassed at work
I feared this because of a letter that, as you know, was sent to my employer promising that I would be featuring prominently in the Burzynski movie
Nobody asked me for my opinion or to give a statement or to respond or clarify; they went straight to my boss
Fine
I’ve had wacky people contact my employers in the past
I fully expect it to happen in the future
Clips of this show, episode 13, were included in the movie
This is the episode that was quoted in the letter on my university chancellor
As it turned out, our faces were blurred, our names obscured, and our voices were altered
No real identifying information
Which, you know, I’m OK with
However, there are some problems here
1) What was served by contacting my employer other than to scare me
How dare the filmmakers say that we’re terrorizing people when they are doing just that
2) Someone asked me about a quote,
“we’re coming for you, you little polish sausage you.”
The thing is, the quote is patently absurd if my name is shown, something that everyone here jumped on, like I hoped you would during the original episode
That joking was not conveyed to the skeptics in the theater audience
This might be due to the fact that not only were we given scary voices but also that apparently every time we appeared scary music played in the background
It’s clear that the reason I’m in the movie in the capacity I am, as chief bad guy, is because I’m on video talking about the Burzynski Clinic
And this leads me to another thing that Brian mentioned
That when we kind of appeared on the screen, they put up a title card type thing that said,
“skeptical teleconference”
or something like that, and that a woman at the end of the show, wanted to know,
“How did you get this footage of these scheming skeptics?”
Um….we publicize our show constantly?
If you can’t have real clandestine drama, you might as well make it up
My favorite bit was a tweet that I got around this time where a new account who followed like 10 people I do said,
“It’s really interesting when you talk about Burzynski on the show
Could you do that more?”
Really, Eric?
(Do you know it was Eric ? After all, you thought I was Eric)
Bob Blaskiewicz
Yeah, I have a feeling it’s Merola
That’s just me though
He’s way too invested in the hashtag in his movie to just let it drop
http://www.chapmancentral.co.uk/blahg/2013/03/burzynski-another-fact-blind-troll-who-predicted-that/#comments
Do you think I’m two years old?
(Your “fact-checking” ability makes me wonder)
I am interested in ultimately seeing it
I’m asking that the producer send a review copy to the James Randi Educational Foundation so a proper review can be done
(As if jref is a “reliable source”)
Or you could screen it in Minneapolis
Next week works for me, Eric, if you’re free
Another thing
News broke on the 7th of January in skeptical circles that the FDA was conducting an audit of the clinic
A patient in the movie apparently said that she had been receiving a brain scan when she heard that the Clinic was being investigated again
This means that material was added to the movie after the 7th of January
The Burzynski Birthday Fundraiser was announced by PZ Myers on the 6th
So there was more than enough time for the filmmaker to clarify exactly what was meant in that episode when I said that there was going to be a little present on his birthday
(That “present” PZ Myers was offering up ?)
Skeptics evilly, and with malice aforethought, raised $14.5K dollars for St. Jude’s
We then challenged the Clinic to match us, and it didn’t
That the director did not mention this fact seems to me inexcusable, making us look like we are big meanos who hate babies and morality
(He could have mentioned your “Fave,” PZ Myers)
This demonization is unfair and at the expense of the truth–if you ever read theotherburzynskipatientgroup blog you know whose side I’m on
If he used the video clip of us that he cited in his letter to my employer, about us bringing a “present” to Burzynski and knowing what it actually was without clarifying it, well, that just speaks to his regard for completeness and accuracy
No messiah should need such fudging
It suggests to me that he’s forcing evidence into a pre-existing narrative of persecution
(And what do you call what YOU are doing ?)
References:
PZ Myer’s announcement of the Houston Cancer Quack
http://scienceblogs.com/pharyngula/2013/01/06/lets-make-houston-cancer-quack-burzynski-pay/
The Virtual Skeptics episode that appears in the movie:
RJB
rjblaskiewicz:
http://t.co/F79zndTjuZ
Bob Blaskiewicz retweeted
Bobby, did you know that I tried to post a comment on the James Randi Educational Funding (jref) article Written by Brian Thompson , about this, but they did NOT post my response ?
Did you post something about “FREE SPEECH” ?
“Burzynski II” Fails to Convince
Swift”
http://www.randi.org/site/index.php/swift-blog/2050-qburzynski-iiq-is-more-of-the-same.html
My 1st-hand Review of Orac’s 2nd-Hand Review – Burzynski: Cancer is Serious Business, Part II
Burzynski critic Orac blogged about “Burzynski: Cancer is Serious Business, Part II”
https://stanislawrajmundburzynski.wordpress.com/2013/03/14/my-1st-hand-review-of-oracs-2nd-hand-review-burzynski-cancer-is-serious-business-part-ii
rjblaskiewicz:
Bobby, does this mean it will be punctuated correctly, but NOT “Fact-Checked” ?
rjblaskiewicz:
Bobby, it did NOT help
rjblaskiewicz:
rjblaskiewicz:
Not really. 🙂
That’s what I thought, Bobby
rjblaskiewicz:
rjblaskiewicz:
rjblaskiewicz:
Bobby, what was that about
“many interesting and civil discussions” ?
Bobby, you can’t always get what you want
But if you try sometime, you just might find
you get what you need
rjblaskiewicz:
Bobby, let me guess
You are so busy tweeting about penises that you do NOT have enough time to “Fact-Check” ?
You do know FDA required ?
” … in 1997, his medical practice was expanded to include traditional cancer treatment options such as
chemotherapy,
gene targeted therapy,
immunotherapy and
hormonal therapy
in response to FDA requirements that cancer patients utilize more traditional cancer treatment options in order to be eligible to participate in the Company’s
Antineoplaston CLINICAL TRIALS
http://www.sec.gov/Archives/edgar/data/724445/000091205702038660/a2091272z10qsb.txt
rjblaskiewicz:
Comes with the territory! 🙂
Yes it does, Bobby
You’ve just been Insolently pwned
