Critiquing: Amelia’s family ‘mislead by cancer clinic’

6/5/2013 – This article was published By Getreading [1]

“A family who sent their terminally ill daughter to the US for experimental treatment said the clinic misled them about her chances of survival

“The parents of Pride of Reading Child of Courage winner, four-year-old Amelia Saunders who died in January, say they were told she had a 54 per cent chance of survival with the clinical trial in Houston, Texas

“However mum Chantal Saunders, 36, believes the actual figure was just one per cent
——————————————————————
Based on what ?
——————————————————————
“A BBC Panorama investigation shown on Monday questioned whether the Burzynski Clinic was “selling hope” to families
——————————————————————
Aren’t all cancer treatments “selling hope” ?
——————————————————————
“In it, Mrs Saunders said:”

“I think that’s wrong” [54 per cent figure]

“I think that’s a complete lie”

“I think one per cent is a more accurate figure.”
——————————————————————
Based on what ?
——————————————————————
“Dad Richard, 35, says he has only found two patients of Dr Stanislaw Burzynski with the same rare brain tumour as Amelia who survived long-term”

“Mr Saunders, from Lower Earley, said:”

“It didn’t work for Amelia but we absolutely know it works for other people.”

“It’s hard to believe it works for Amelia’s tumour type and that’s what we have found tricky”

“I’ve had all sorts of excuses from them as to why they won’t release data on how many patients they treat and the outcomes”

“I think the figures Panorama were given show there was 700-odd patients they treated and something like 15 per cent survived over five years
——————————————————————
Panorama’s figures were:

“They say 776 patients with brain tumours were treated in trials before 2008.”

“And that 15.5% had survived more than five years, which compares favourably to other treatments.” [2]
——————————————————————
“If you look at all brain tumours that’s almost identical to any other treatment”
——————————————————————
Based on what ?
——————————————————————
“If you look at Amelia’s tumour alone you’re looking at almost zero per cent.”

Amelia was diagnosed with a rare tumour on her brain stem in February last year

“Her devastated family was told by doctors there was no treatment available in Britain”

“After finding out about Burzynski’s clinical trial, which has been running for 20 years, Amelia’s family decided to raise the money needed for the ‘antineoplaston’ treatment – a staggering £250,000 – in just a few weeks through donations”

Mrs Saunders, who also has two-year-old daughter Charlotte, said:”

“He was giving us more hope than I think realistically there was”
——————————————————————
Based on what ?
——————————————————————
Mr Saunders added:”

“We find it very hard to believe the treatment did nothing”

“We did no chemotherapy with her”

“To keep it stable for 11 months is incredible in itself, but how do we prove that?”

“We can’t.”
——————————————————————
Why not ?

Were there not scans ?
——————————————————————
“In November last year Dr Burzynski told the family a new scan showed Amelia’s tumour was breaking down

UK doctors at Great Ormond Street Hospital in London said it actually showed the tumour was continuing to grow
——————————————————————
Based on what ?

Great Ormond Street Hospital having 36 years of experience treating patients with antineoplastons ?
——————————————————————
“The family decided to stop the Burzynski treatment a few weeks later”
——————————————————————
Based on what ?
——————————————————————
“Although the family now has doubts over Burzynski’s success rate, Richard says they have spoken to others who have been helped by the drug”
——————————————————————
“The family now has doubts over Burzynski’s success rate” ?

What was all this, then ?

a) “A family who sent their terminally ill daughter to the US for experimental treatment said the clinic misled them about her chances of survival

b) “However mum Chantal Saunders, 36, believes the actual figure was just one per cent

c) “I think that’s wrong” [54 per cent figure]

“I think that’s a complete lie”

d) “I think one per cent is a more accurate figure.”

e) “He was giving us more hope than I think realistically there was”
——————————————————————
“He said:”

“We asked repeatedly throughout the time Amelia was under treatment for evidence to back up his claims, and he at no point produced this”

“We found patients ourselves through Facebook, forums, email and word of mouth”

“We want everyone to know that there are people who are living proof that the treatment works – but it just didn’t for our little girl”

“We just wish Dr Burzynski would speak the truth, and release proper, tangible results.”
——————————————————————
So, you wanted him to “release proper, tangible results” before the clinical trials were finished ?
——————————————————————
“The Saunders family have donated the rest of the money raised for Amelia to cancer research and other charities”

“This included £50,000 to a cancer treatment research team at the University of Nottingham

“Its Professor Richard Grundy said it was “unethical” for Dr Burzynski not to publish results from his trial
——————————————————————
So, you wanted him to “publish results from his trial” before the clinical trial was finished ?
——————————————————————
“Unfortunately the results from Dr Burzynski’s clinic are not published in any form that’s acceptable to the scientific community,” he said”
——————————————————————
So a donation of £50,000 was made, which included to a cancer treatment research team at the University of Nottingham, where Professor Richard Grundy; who exhibits NO knowledge of antineoplastons in this article, is

How “convenient” for him and the University

In my opinion,’ it is “unethical” for Professor Grundy to NOT share his findings re Dr. Burzynski’s 2003-2010 phase 2 clinical trial preliminary reports [3]

He reminds of the situation that Burzynski found himself in when he relates that clinical investigators decided to change the protocol without his approval on a clinical trial of antineoplastons

Seriously, who in their right mind would ignore the input of the inventor and developer of a medicine with close to 20 years of clinical experience, and think they know more than that person ? [4]
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REFERENCES:
======================================
[1] – Reading Post, Amelia’s family ‘mislead by cancer clinic’, By Getreading | 5 Jun 2013 07:59
——————————————————————
http://www.getreading.co.uk/news/amelia-saunders-family-mislead-burzynski-4051287
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[2] – 8/4/2013 – Critiquing Dr David H. “Orac” Gorski, M.D., Ph.D, LIAR: Stanislaw Burzynski versus the BBC:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/04/critiquing-dr-david-h-orac-gorski-m-d-ph-d-liar-stanislaw-burzynski-versus-the-bbc/
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[3] – 9/22/2013 – Critiquing Wikipedia: Burzynski Clinic – 2013 BBC documentary, Curing cancer or ‘selling hope’ to the vulnerable?;
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/22/critiquing-wikipedia-burzynski-clinic-2013-bbc-documentary-curing-cancer-or-selling-hope-to-the-vulnerable/
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[4] – Critiquing: National Cancer Institute (NCI) at the National Institutes of Health (NIH) CancerNet “fact sheet”:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/19/critiquing-national-cancer-institute-nci-at-the-national-institutes-of-health-nih-cancernet/
======================================

Critiquing Wikipedia: Burzynski Clinic – 2013 BBC documentary, Curing cancer or ‘selling hope’ to the vulnerable?

Wikipedia must be too busy accusing me of using multiple Internet I.P. addresses to try and change every wiki article under the sun, instead of keeping their Burzynski article up-to-date

I await the in-depth analysis which breaks down my blog, Twitter, and Internet activity, showing that it was humanly possible for me to do all that has been claimed

But then again, maybe I’m NOT human !

HAL ?

Is that you HAL ?

Anywho, WP took a crack at addressing the British Broadcasting Corporation’s (BBC) Panorama documentary [1]

I did some critiques on the documentary article, documentary, and WP’s “credible source,” Dr. David H. Orac … Gorski [2-4]

“Burzynski exploits a legal loophole”by treating patients” with antineoplastons do so as part of a clinical trial, so the drug does not need a licence” for twenty years.” [66]

“Legal loophole” ?

Really ??

Not so much

It’s the law

“The Skeptics™” have had years to get it changed in Congress if it were a “legal loophole”

“According to Watford Observer, the mother of Luna Petagine, a young girl with a brain tumor, “cast doubt” on Burzynski’s “expensive treatment.” [67]

“Expensive treatment” ?

Based on what objective criteria ? [5-6]

The Reading Post said, the Panorama investigation shown on Monday questioned whether the Burzynski Clinic was ‘selling hope’to families” which doubted the statistics provided by the Burzynski Clinic. [68]

Based on what objective criteria ?

“They say 776 patients with brain tumours were treated in trials before 2008.”

“And that 15.5% had survived more than five years, which compares favourably to other treatments.” [6] (see #13)

Where’s Wikipedia’s survival rates for:

a) Chemotherapy

b) Radiation Therapy

c) Radiotherapy

d) Other

and their comparison of possible adverse effects of chemotherapy, radiation therapy, radiotherapy, other, compared to antineoplastons ?

The issues I had with the documentary were:

1. “The report includes interviews with experts like Professor Richard Grundy of Nottingham Children’s Hospital”

“Prof Richard Grundy treats children with cancer, and runs one of the UK’s biggest research projects into brain tumours.”

“He says it is “unethical” for Dr Burzynski not to share his findings:”

In my ‘opinion,’ it is “unethical” for Professor Grundy to NOT share his findings re Dr. Burzynski’s 2003-2010 phase 2 clinical trial preliminary reports [7]

2. “Unfortunately the results from Dr Burzynski’s clinic are not published in any form that’s acceptable to the scientific community.””

Explain [7]

3. Dr Jeanine Graf

“She sometimes treats patients from the Burzynski Clinic who have become critically ill, but she has never known any of them survive.”

How many patients ?

Richard Bilton asked for numbers from Burzynski, so he should be consistent and have asked Dr. Graf the same question

4. “He must believe in what he’s doing, but I have not been convinced by the existing scientific literature that his therapy has any efficacy.”

Where is Dr. Graf’s “in-depth” review of Dr. Burzynski’s above-listed publications ? [7]
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REFERENCES:
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[1] – Wikipedia: Burzynski Clinic – Legal Issues: 2013 BBC documentary, Curing cancer or ‘selling hope’ to the vulnerable?
——————————————————————
http://en.wikipedia.org/wiki/Burzynski_Clinic
——————————————————————
http://en.m.wikipedia.org/wiki/Burzynski_Clinic
——————————————————————
http://en.wikipedia.org/w/index.php?title=Burzynski_Clinic&mobileaction=toggle_view_desktop
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[2] – 6/4/2013 – The British are Coming, The British are Coming: Critiquing
“Curing cancer or ‘selling hope’ to the vulnerable?”
:

——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/06/04/the-british-are-coming-the-british-are-coming-critiquing-curing-cancer-or-selling-hope-to-the-vulnerable/
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[3] – 6/7/2013 – IT MAY NOT BE SCIENCE: Critiquing “Curing cancer or ‘selling hope’ to the vulnerable?”:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/06/07/it-may-not-be-science-critiquing-curing-cancer-or-selling-hope-to-the-vulnerable/
======================================
[4] – 8/4/2013 – Critiquing Dr David H. “Orac”
Gorski, M.D., Ph.D, LIAR: Stanislaw Burzynski versus the BBC:

——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/04/critiquing-dr-david-h-orac-gorski-m-d-ph-d-liar-stanislaw-burzynski-versus-the-bbc/
======================================
[66] – Richard Bilton

——————————————————————
http://www.radiotimes.com/episode/wxxjy/panorama–cancer-hope-for-sale—panorama
——————————————————————
there for posterity on YouTube

http://t.co/YOlSjCg1d0
——————————————————————
THIS IS IT!

http://fb.me/LYCqmKrh
——————————————————————
http://t.co/6cDJapt6eM
——————————————————————
http://t.co/nFpwlQg275
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[67] – Watford Observer
——————————————————————
http://www.watfordobserver.co.uk/news/10470494.print/
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[5] – 4/25/2013 – Burzynski: Costs of Cancer treatments:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-costs-of-cancer-treatments/
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[6] – 7/18/2013 – Critiquing: In which the latest movie about Stanislaw Burzynski “cancer cure” is reviewed…with Insolence:
——————————————————————
See #10
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/07/18/critiquing-in-which-the-latest-movie-about-stanislaw-burzynski-cancer-cure-is-reviewed-with-insolence-2/
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[68] – Reading Post
——————————————————————
http://www.getreading.co.uk/news/amelia-saunders-family-mislead-burzynski-4051287
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[7] – 8/7/2013 – Burzynski: Phase II Clinical Trials Preliminary Reports:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/07/burzynski-phase-ii-clinical-trials-preliminary-reports/
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Critiquing https://theotherburzynskipatientgroup.wordpress.com

Critiquing https://theotherburzynskipatientgroup.wordpress.com

Robert J. (Bob) Blaskiewicz operates The Other Burzynski Patient Group (TOBPG)

The problem is:

1. Bob Blaskiewicz Faux Skeptic Exposed! does NOT want to debate or want people to consider the failures of Science Based Medicine compared to Burzynski, because he has an agenda

2. @rjblaskiewicz is a known LIAR

Making unsubstantiated claims like this:

Bob Blaskiewicz (@rjblaskiewicz) tweeted at 9:45am – 25 Aug 13:

@dixon_frederick @AlaaTheWarrior Actually, he CLAIMS a success rate, but is unable to publish. Suspicious: clinicaltrials.gov/ct2/results?te…

� � � � � � � � � � � � � � � � �
374 – TOTAL CHILDREN DIED:
Science Based Medicine

� � � � � � � � � � � � � � � � �
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[6] .9/15/1999 – 29 / 85% died
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[9] .9/15/1994 – 51 / 88% – children died
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[8] 1/1998 – 8 / 89% of 9 children died of their disease at median of 44 weeks
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[5] .10/21/2002 – 12 / 100% – all children patients died
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[2] 5/1/2010 – 18 – children patients have died from disease progression
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[3] 2/2008 – All 30 / 100% – children have died
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[4] 1/1/2005 – 33 / 100% – children died of disease progression
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[1] 4/2011 – 63 / 100% – children died
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[7] .3/15/1999 – 130 / 100% – children died
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� � � � � � � � � � � � � � � � �
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COMBINED:
======================================
� � � � � � � � � � � � � � � � �
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[1] 4/2011 – children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)
——————————————————————
[1] 4/2011 – children with DIPG
——————————————————————
[1] 5/1/2010 children with newly diagnosed diffuse intrinsic pontine glioma
——————————————————————
[1] 5/1/2010 children with diffuse intrinsic pontine gliomas (DIPGs)
——————————————————————
[1] 5/1/2010 Pediatric patients with newly diagnosed DIPGs
——————————————————————
[3] 2/2008 – children with diffuse intrinsic brain stem glioma
——————————————————————
[3] 2/2008 – diffuse intrinsic pontine glioma
——————————————————————
[4] 1/1/2005 – newly diagnosed diffuse brainstem glioma in children
——————————————————————
[4] 1/1/2005 – children with newly diagnosed diffuse brainstem glioma
——————————————————————
[4] 1/1/2005 – newly diagnosed, diffuse, intrinsic brain stem glioma
——————————————————————
[5] .10/21/2002 – typical diffuse pontine glioma
or
histologically proven anaplastic astrocytoma/glioblastoma multiforme located in the pons

——————————————————————
[5] .10/21/2002 – pontine glioma patients
——————————————————————
[5] .10/21/2002 – paediatric patients with pontine gliomas
——————————————————————
[5] .10/21/2002
brain tumours
brain stem glioma

——————————————————————
[5] .10/21/2002
Histological diagnoses included

8 – glioblastoma multiforme
5 – no histology
3 – anaplastic astrocytoma
3 – astrocytoma with no other specification
1 – pilocytic astrocytoma

——————————————————————
[6] .9/15/1999 – Brainstem gliomas
——————————————————————
[6] .9/15/1999 – diffuse intrinsic pontine tumor
——————————————————————
[6] .9/15/1999 – high grade glioma was required for nonpontine brain stem tumors
——————————————————————
[7] .3/15/1999 children with newly diagnosed brainstem tumor
——————————————————————
[7] .3/15/1999 tumors arising in the pons
——————————————————————
[7] .3/15/1999 diffusely infiltrating pontine lesion
——————————————————————
[8] 1/1998 – children with diffuse pontine gliomas
——————————————————————
[8] 1/1998 – pediatric malignancies
——————————————————————
[8] 1/1998 – Diffuse pontine gliomas
——————————————————————
[9] .9/15/1994 – Brain stem gliomas
——————————————————————
[9] .9/15/1994 – childhood brain tumors
——————————————————————
[9] .9/15/1994 – children with brain stem gliomas
——————————————————————
[9] .9/15/1994 – patients with diffuse intrinsic brain stem gliomas
——————————————————————
[9] .9/15/1994 – children with diffuse intrinsic brain stem gliomas
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� � � � � � � � � � � � � � � � �
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# OF CHILDREN
======================================
� � � � � � � � � � � � � � � � �
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[8] 1/1998 – 9 / 100% – consecutive children
——————————————————————
[5] .10/21/2002 – 20 – enrolled (9 male / 11 female)
——————————————————————
[2] 5/1/2010 – 20 – children accrued
——————————————————————
[3] 2/2008 – 31 – children enrolled
——————————————————————
[4] 1/1/2005 – 33 / 100% – patients enrolled
——————————————————————
[6] .9/15/1999 – 34 / 100% – patients enrolled
——————————————————————
[1] 4/2011 – 63 / 100% – children enrolled in study
——————————————————————
[9] .9/15/1994 – 66 children
——————————————————————
[7] .3/15/1999
130 – eligible patients
66 – arm 1
64 – arm 2
======================================
� � � � � � � � � � � � � � � � �
======================================
# OF EVALUABLE CHILDREN
======================================
� � � � � � � � � � � � � � � � �
======================================
[8] 1/1998 – 9 / 100% – consecutive children evaluable
——————————————————————
[5] .10/21/2002 – 12 – Evaluable patients
——————————————————————
[2] 5/1/2010 – 20 – children evaluable
——————————————————————
[3] 2/2008 – 30 – eligible and evaluable for survival and toxicity
——————————————————————
[4] 1/1/2005 – 33 / 100% – patients evaluable
——————————————————————
[6] .9/15/1999 – 34 / 100% – patients evaluable
——————————————————————
[9] .9/15/1994 – 58 / 100% – evaluable patients
——————————————————————
[1] 4/2011 – 63 / 100% – children evaluable
——————————————————————
[7] .3/15/1999
130 – evaluable patients
66 – arm 1
64 – arm 2
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� � � � � � � � � � � � � � � � �
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AGE RANGE OF CHILDREN
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� � � � � � � � � � � � � � � � �
======================================
[5] .10/21/2002 – 3-17 years of age
——————————————————————
[6] .9/15/1999 – 3.6–15.4 years
——————————————————————
[3] 2/2008 – 3–21 – age children enrolled
——————————————————————
[4] 1/1/2005 – 3-21 years – eligible for current multiinstitutional study
——————————————————————
[7] .3/15/1999 3-21 years of age
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� � � � � � � � � � � � � � � � �
======================================
MEDIAN AGE OF CHILDREN
======================================
� � � � � � � � � � � � � � � � �
======================================
[5] .10/21/2002 – 6 years – median age
——————————————————————
[4] 1/1/2005 – 6.4 years – Median age at diagnosis
——————————————————————
[9] .9/15/1994 – 7.5 years – mean age at diagnosis
——————————————————————
[6] .9/15/1999 – 7.8 years – median age of patients
——————————————————————
[3] 2/2008 – 8 – median age (3–14 years)
——————————————————————
[2] 5/1/2010 – 8.3 years – mean age
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� � � � � � � � � � � � � � � � �
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1 YEAR OR LESS SURVIVAL RATES
======================================
� � � � � � � � � � � � � � � � �
======================================
[1] 4/2011 – 9 / 14% – mean 1-year Event-Free Survival (EFS)
——————————————————————
[1] 4/2011 – 14 / 21.9% – no evidence produced 1-year Event-Free Survival (EFS) rate higher than
——————————————————————
10/2006..5 / 26% – 1 year: Burzynski Antineoplastons: Progression-Free Survival Rate (PFS): Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
——————————————————————
[7] 3/15/1999 – 17 / 27.0% – ARM 2: 1 year Patients Surviving: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
10/2004..9 / 29%Burzynski Antineoplastons: 1 year Progression-Free Survival (PFS): Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG): Special Exception (SE) (Pg. 386)
——————————————————————
[7] 3/15/1999 – 40 / 30.9% – ARM 1: 1 year Patients Surviving: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
[9] .9/15/1994 – 20 / 35% – 1 year Overall Survival
——————————————————————
3/2006..39%Burzynski Antineoplastons Patients with high-grade, recurrent and progressive BRAINSTEM GLIOMAS: Progression-Free Survival (PFS) at 6 months: BRAINSTEM GLIOMA (BSG) (Pgs. 40 + 44-45)
——————————————————————
[1] 4/2011 – 25 / 40% – mean 1-year Overall Survival (OS)
——————————————————————
10/2004..12 / 41%Burzynski l: 1 year Progression-Free Survival (PFS): Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) (Pg. 386)
——————————————————————
3/2004 – 43%Burzynski Antineoplastons – % of responding Patients didn’t develop Progression: 6/1/2003 Protocol – BT-11 – BRAIN STEM GLIOMA (Pg. 51)
——————————————————————
[4] 1/1/2005 – 16 / 48% – 1 year estimated Survival rate
——————————————————————
10/2006..10 / 53%Burzynski Antineoplastons 1 year Overall Survival Rate (OS): Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
——————————————————————
3/2004 – 61%Burzynski Antineoplastons % of Objective Response (OR) Patients hadn’t had Progression: 6/1/2003 Protocol – HIGH-GRADE GLIOMA (Pg. 53)
——————————————————————
[3] 2/2008 – 27 / 90% – 1 year  - Overall survival
======================================
� � � � � � � � � � � � � � � � �
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LESS THAN 1 YEAR SURVIVAL (MST)
======================================
� � � � � � � � � � � � � � � � �
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[7] 3/15/1999 – 5 months – ARM 2: Median time to Disease Progression: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
3/2006.-.6 months – Patients with Recurrent Tumors Survive no more than, despite standard treatment: (Pgs. 40 + 45-46)
——————————————————————
[7] 3/15/1999 – 6 months – ARM 1: Median time to Disease Progression: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
2003 – 6.4 monthsBurzynski Antineoplastons Median Survival: Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 Special Exception (SE) (Pg. 99)
——————————————————————
2003 – 7 monthsBurzynski Antineoplastons Median Survival: Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 (Pg. 99)
——————————————————————
3/2004 – 7 monthsBurzynski Antineoplastons – Progression-Free Survival (PFS): 6/1/2003 Protocol – BT-11 BRAIN STEM GLIOMA (Pg. 51)
——————————————————————
3/2004 – 7 monthsBurzynski Antineoplastons Progression-Free Survival (PFS): Protocol – subgroup very difficult to treat recurrent diffuse intrinsic BRAIN STEM GLIOMA (Pg. 52)
——————————————————————
[7] 3/15/1999 – 8 months – ARM 2: Median time to Death: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992 – 10/1997) 2004 (Pg. 58)
——————————————————————
[7] 3/15/1999 – 8 months – ARM 2: Median Overall Survival from Diagnosis (OSD): Median time to Death: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
[7] 3/15/1999 – 8 months – ARM 2: Median Overall Survival from start of Treatment (OST): Median time to Death: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
[7] 3/15/1999 – 8.5 months – Median Survival (MST): standard radiation therapy in combination with chemotherapy (RAT) (Mandell et al.) (6/1992–10/1997) children with newly diagnosed diffuse intrinsic BRAIN STEM TUMORS: results of pediatric oncology group
——————————————————————
[7] 3/15/1999 – 8.5 months – ARM 1: Median Overall Survival from start of Treatment (OST): Median time to Death: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
[7] 3/15/1999 – 8.5 months – ARM 1: Median time to Death: Median Overall Survival from Diagnosis (OSD): Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
3/2004 – 10.3 monthsBurzynski Antineoplastons – Median Overall Survival from start of Treatment (OST): 6/1/2003 Protocol – BT-11 BRAIN STEM GLIOMA (Pg. 51)
======================================
� � � � � � � � � � � � � � � � �
======================================
1 YEAR SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2004 – 12 months (1 year)Burzynski Antineoplastons: Progression-Free Survival (PFS): 6/1/2003 Protocol – HIGH-GRADE GLIOMA (Pg. 53)
======================================
� � � � � � � � � � � � � � � � �
======================================
1+ YEAR SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2004 – 13.7 months (1 year 1.7 months)Burzynski Antineoplastons: Median Overall Survival from Diagnosis (OSD): 6/1/2003 Protocol – BT-11 BRAIN STEM GLIOMA (Pg. 51)
——————————————————————
4/2007 – 16.4 months (1 year 4.4 months)Burzynski Antineoplastons(ANP): Median Survival (MST): Protocol – newly diagnosed diffuse, intrinsic BRAINSTEM GLIOMAs (NDBSG) BT-11 (Pg. 206)
——————————————————————
3/2004 – 17 months (1 year 5 months) – Median Survival without Treatment (Pg. 53)
——————————————————————
2006 – 19.9 months (1 year 7.9 months) – Median Survival Time (MST): next best traditional standard of care study (Pg. 172)
——————————————————————
2006 – 19.9 months (1 year 7.9 months)Burzynski Antineoplastons (ANP): Median Survival Time (MST): Treatments for Astrocytic Tumors – recurrent and progressive tumor: Treatment of diffuse, intrinsic BRAINSTEM GLIOMA in children (Pg. 172)
======================================
� � � � � � � � � � � � � � � � �
======================================
2 YEAR SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2006 – 2 years – Most Patients with BRAINSTEM GLIOMA fail standard radiation therapy and chemotherapy and don’t survive longer: (Pgs. 40 + 45-46)
——————————————————————
[7] 3/15/1999 – 4 / 6.7% – ARM 2: 2 year Patients Surviving: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
[7] 3/15/1999 – 7% – 2 year Overall Survival (OS): standard radiation therapy in combination with chemotherapy (RAT) (Mandell et al.) (6/1992–10/1997) children with newly diagnosed diffuse intrinsic BRAIN STEM TUMORS: results of pediatric oncology group
——————————————————————
[7] 3/15/1999 – 9 / 7.1% – ARM 1: 2 year Patients Surviving: Protocol – easier to treat cases of newly diagnosed BRAIN STEM (tumor) GLIOMA patients: radiation therapy and chemotherapy with cisplatin (Mandell et al.) (6/1992–10/1997) 2004 (Pg. 58)
——————————————————————
Less than 10% – 2 year Survival: standard radiation therapy: for newly diagnosed diffuse intrinsic BRAIN STEM GLIOMA (DBSG)
——————————————————————
[3] 2/2008 – 3 / 10% – 2 years – Overall survival
——————————————————————
10/2006..3 / 16% – 2 years: Burzynski Antineoplastons: Progression-Free Survival Rate (PFS): Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
——————————————————————
10/2006..6 / 32% – 2 year Overall Survival Rate (OS): Burzynski Antineoplastons: Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
——————————————————————
2003 – 4 / 33.3% – 2 year Survival: Burzynski Antineoplastons Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 (Pgs. 91-92)
——————————————————————
3/2006 – 39% – 2 year Overall Survival: Burzynski Antineoplastons: Patients with high-grade, recurrent and progressive BRAINSTEM GLIOMAS (BSG) (Pgs. 40 + 44-45)
——————————————————————
4/2007 – 8 / 40% – 2 year Overall Survival (OS): Burzynski Antineoplastons (ANP): Protocol – newly diagnosed diffuse, intrinsic BRAINSTEM GLIOMAs (NDBSG) BT-11 (Pg. 206)
——————————————————————
2004 – 42% – 2 year Patients (Surviving) Survival: Burzynski Antineoplastons: 6/1/2003 Protocol – BRAIN STEM GLIOMA (Pgs. 52-53)
——————————————————————
10/2004..13 / 45% – 2 year Overall Survival (Survival: Special Exception (SE)) Burzynski Antineoplastons: Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) (Pg. 386)
——————————————————————
2006 – 14 / 46.7% – 2 year Overall Survival (OS) (%) – Efficacy: Burzynski Antineoplastons (ANP): Treatments for Astrocytic Tumors – recurrent and progressive tumor: Treatment of diffuse, intrinsic BRAINSTEM GLIOMA in children (Pg. 172)
——————————————————————
2006 – 30 / 46.7% – 2 year Overall Survival (OS) (%) – Efficacy: next best traditional standard of care study (Pg. 172)
——————————————————————
7/2005 – 5 / 50% – 2 year Overall Survival: Burzynski Antineoplastons: children less than 4 years old with inoperable BRAIN STEM GLIOMAs (BSG) BT-11 (study and Special Exception (SE)) (Pg. 300)
——————————————————————
2006 – 6 / 60% – 2 year Overall Survival (OS) (%) – Efficacy: Burzynski Antineoplastons (ANP) – recurrent and progressive (RPS) tumors in children aged <4y: children less than 4 years old with inoperable BRAIN STEM GLIOMAS (Pg. 172) 2005
——————————————————————
2006 – 6 / 60% – 2-year Survival rate: Burzynski Antineoplastons (ANP) – children aged <4 years diagnosed with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) treated with ANP (Pg. 173) 2005
� � � � � � � � � � � � � � � � �
======================================
2+ YEARS PATIENTS SURVIVED
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2006 – 2+ years – Most Patients with Newly Diagnosed High-Grade BRAIN STEM GLIOMAS (HBSG) don’t Survive more than: (Pgs. 40 + 45-46)
——————————————————————
2006 – 12 / >40% – 2+ year patients survived Burzynski Antineoplastons (ANP) recurrent and progressive diffuse intrinsic BRAINSTEM GLIOMA (DBSG) (Pg. 173)
======================================
� � � � � � � � � � � � � � � � �
======================================
3 YEAR OVERALL SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
[9] .9/15/1994 – 7 / 11% – 3 years Overall Survival
======================================
� � � � � � � � � � � � � � � � �
======================================
4+ YEARS FROM START OF TREATMENT
======================================
� � � � � � � � � � � � � � � � �
======================================
2003 – 4+ years – 1 alive – From start of Treatment: Burzynski Antineoplastons Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 (Pgs. 91-92)
======================================
� � � � � � � � � � � � � � � � �
======================================
LONG TERM SURVIVORS
======================================
� � � � � � � � � � � � � � � � �
======================================
2003 – 5+ years – 1 alive – Burzynski Antineoplastons: From start of Treatment: Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 (Pgs. 91-92)
——————————————————————
[7] 3/15/1999 – 0% – 5 year Overall Survival (OS): standard radiation therapy in combination with chemotherapy (RAT) (Mandell et al.) (6/1992–10/1997) children with newly diagnosed diffuse intrinsic BRAIN STEM TUMORS: results of pediatric oncology group
——————————————————————
[6] .9/15/1999 – 5 / 15% – long term survivors who remained in continuous remission after mean follow-up period of 79 months {6 years 7 months} (46–104 months [3 years 10 months – 8 years 8 months])
——————————————————————
10/2006..3 / 16% – 5 year Overall Survival Rate (OS): Burzynski Antineoplastons: Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
——————————————————————
10/2004..5 / 16% – 5 years: Burzynski Antineoplastons: Overall Survival (Survival: Special Exception (SE)) Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG): Special Exception (SE) (Pg. 386)
——————————————————————
7/2005 – 2 / 20% – 5 year Overall Survival: Burzynski Antineoplastons: children less than 4 years old with inoperable BRAIN STEM GLIOMAs (BSG) BT-11 (study and Special Exception (SE)) (Pg. 300)
——————————————————————
2005 – 2 / 20% – 5 year Overall Survival (OS) (%) – Efficacy: Burzynski Antineoplastons (ANP) – recurrent and progressive (RPS) tumors in children aged <4y: children less than 4 years old with inoperable BRAIN STEM GLIOMAS 2006 (Pg. 172)
——————————————————————
2005 – 2 / 20% – 5-year Survival rate: 2006 Burzynski Antineoplastons (ANP) – children aged <4 years diagnosed with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) treated with ANP (Pg. 173)
——————————————————————
3/2006 – 22%Burzynski Antineoplastons 5 year Overall Survival: Patients with high-grade, recurrent and progressive BRAINSTEM GLIOMAS (BSG) (Pgs. 40 + 44-45)
——————————————————————
10/2004..7 / 24% – 5 years: Burzynski Antineoplastons: Overall Survival (Survival: Special Exception (SE)) Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) (Pg. 386)
——————————————————————
4/2007 – 6 / 30% – 5 year Overall Survival (OS): Burzynski Antineoplastons ((ANP): Protocol – newly diagnosed diffuse, intrinsic BRAINSTEM GLIOMAs (NDBSG) BT-11 (Pg. 206)
——————————————————————
2005 – 9 / 30% – 5 year Overall Survival (OS) (%) – Efficacy: Burzynski Antineoplastons (ANP): Treatments for Astrocytic Tumors – recurrent and progressive tumor: Treatment of diffuse, intrinsic BRAINSTEM GLIOMA in children 2006 (Pg. 172)
——————————————————————
2005 – 9 / 30% – 5+ year patients survived Burzynski Antineoplastons (ANP) recurrent and progressive diffuse intrinsic BRAINSTEM GLIOMA (DBSG) 2006 (Pg. 173)
——————————————————————
2003 – 2 / 17% – 5+ years Alive and Tumor Free since Initial Diagnosis: Burzynski Antineoplastons: Protocol patients with recurrent diffuse intrinsic BRAIN STEM GLIOMA: BT-11 (Pgs. 91-92)
——————————————————————
9 / 30% – 5+ year patients survived 2006 Burzynski Antineoplastons (ANP) recurrent and progressive diffuse intrinsic BRAINSTEM GLIOMA (DBSG) (Pgs. 172-173)
======================================
� � � � � � � � � � � � � � � � �
======================================
SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
[2] 5/1/2010 – 6.9 months – Progression-Free Survival (PFS)
——————————————————————
[5] .10/21/2002 – 8 months – Overall Median Survival
——————————————————————
[3] 2/2008 – 9 months (3–36 months [3 years]) – Median Survival (MS)
——————————————————————
[2] 5/1/2010 – 9.15 months – Median Overall Survival
——————————————————————
[1] 4/2011 – 9.6 months – Median Time to Death
——————————————————————
[4] 1/1/2005 – 12 months (1 year) – Median Survival (MS)
——————————————————————
[6] .9/15/1999 – 12 months (1 year) – Overall Survival (5–104+ months [5 months – 8 years 8+ months])
======================================
2 YEARS 2.3 MONTHS MEDIAN SURVIVAL TIME (MST)
======================================
� � � � � � � � � � � � � � � � �
======================================
2006 – 26.3 months (2 years 2.3 months)Burzynski Antineoplastons (ANP) – Median Survival Time (MST): recurrent and progressive (RPS) tumors in children aged <4y: children less than 4 years old with inoperable BRAIN STEM GLIOMAS 2005 (Pg. 172)
======================================
� � � � � � � � � � � � � � � � �
======================================
3 YEARS MEDIAN OVERALL SURVIVAL FROM DIAGNOSIS (OSD)
======================================
� � � � � � � � � � � � � � � � �
======================================
2004 – 3 years – with treatment, may approach (Pg. 53)
——————————————————————
2004 – 3 years Burzynski Antineoplastons Median Overall Survival from Diagnosis (OSD): 6/1/2003 Protocol – HIGH-GRADE GLIOMA (Pg. 53)
======================================
� � � � � � � � � � � � � � � � �
======================================
5+ YEARS SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2006 – 5+ yearsBurzynski Antineoplastons: Survival in recurrent diffuse intrinsic GLIOBLASTOMAS and anaplastic ASTROCYTOMAS of the BRAINSTEM in a small group of Patients: BRAINSTEM GLIOMA (BSG) Patient with GLIOBLASTOMA (Pgs. 40 + 44-45)
======================================
� � � � � � � � � � � � � � � � �
======================================
6+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
7/2005 – 6+ yearsBurzynski Antineoplastons: Maximum Survival (MS): children less than 4 years old with inoperable BRAIN STEM GLIOMAs (BSG) BT-11 (study and Special Exception (SE)) (Pg. 300)
——————————————————————
6+ yearsBurzynski Antineoplastons Patient with recurrent, diffuse, intrinsic GLIOBLASTOMA MULTIFORME (GBM)
======================================
� � � � � � � � � � � � � � � � �
======================================
6.3 YEARS MEDIAN OVERALL SURVIVAL FROM DIAGNOSIS (OSD)
======================================
� � � � � � � � � � � � � � � � �
======================================
2004 – 6.3 yearsBurzynski Antineoplastons: Median Overall Survival from Diagnosis (OSD): 6/1/2003 Protocols – LOW-GRADE GLIOMA IN CHILDREN (Pg. 50)
======================================
� � � � � � � � � � � � � � � � �
======================================
7+ YEARS LONGEST / MAXIMUM SURVIVAL
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2004 – 7+ yearsBurzynski Antineoplastons: Longest Survival (the Patients are currently alive): Protocol – subgroup very difficult to treat recurrent diffuse intrinsic BRAIN STEM GLIOMA (Pg. 52)
——————————————————————
2006 – 7+ yearsBurzynski Antineoplastons (ANP) – Maximum Survival (MS): children aged <4 years diagnosed with diffuse intrinsic BRAIN STEM GLIOMA (DBSG) treated with ANP (Pg. 173)
======================================
� � � � � � � � � � � � � � � � �
======================================
7.5+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
2004 – 7.5+ yearsBurzynski Antineoplastons Maximum Survival (MS): 6/1/2003 Protocol – BT-11 BRAIN STEM GLIOMA (Pg. 51)
======================================
� � � � � � � � � � � � � � � � �
======================================
9+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
10/2006 – 9+ yearsBurzynski Antineoplastons: Maximum Survival Rate: Protocol – BT-11 BRAINSTEM GLIOMAS and multicentric tumors (MBSG) (Pg. 466)
======================================
� � � � � � � � � � � � � � � � �
======================================
11 YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
10/2004..11 yearsBurzynski Antineoplastons: Maximum Survival: Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG): Special Exception (SE): (high-grade diffuse intrinsic BRAIN STEM GLIOMA (DBSG) recurrent after radiation and chemotherapy) (Pg. 386)
======================================
� � � � � � � � � � � � � � � � �
======================================
12.5+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
2004 – 12.5+ yearsBurzynski Antineoplastons: Maximum Survival (MS): 6/1/2003 Protocol – HIGH-GRADE GLIOMA (Pg. 53)
======================================
� � � � � � � � � � � � � � � � �
======================================
15.5+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
10/2004 – 15.5+ yearsBurzynski Antineoplastons: Maximum Survival: Protocol – patients with diffuse intrinsic BRAIN STEM GLIOMA (DBSG): (high-grade diffuse intrinsic BRAIN STEM GLIOMA (DBSG) recurrent after radiation and chemotherapy) (Pg. 386)
======================================
� � � � � � � � � � � � � � � � �
======================================
17+ YEARS MAXIMUM SURVIVAL (MS)
======================================
� � � � � � � � � � � � � � � � �
======================================
3/2006 – 17+ years (approaching 18 years)Burzynski Antineoplastons: BRAINSTEM GLIOMA (BSG) Maximum Survival for Patient with recurrent, diffuse, intrinsic anaplastic ASTROCYTOMA (Pgs. 40 + 44-45)
======================================
� � � � � � � � � � � � � � � � �
======================================
Burzynski: BRAINSTEM GLIOMAs (DBSG):
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/07/31/burzynski-brainstem-gliomas-dbsg/
======================================
References:
======================================
[1] 4/2011 – children with newly diagnosed diffuse intrinsic pontine gliomas
======================================
Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children’s Oncology Group
http://www.ncbi.nlm.nih.gov/pubmed/21345842/
Neuro Oncol. 2011 Apr;13(4):410-6. doi: 10.1093/neuonc/noq205. Epub 2011 Feb.22
http://www.ncbi.nlm.nih.gov/m/pubmed/21345842/
Neuro-oncology 2011 Apr; 13(4):410-6
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064697/
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064697/pdf/noq205.pdf
the Children’s Oncology Group
http://m.neuro-oncology.oxfordjournals.org/content/13/4/410.long?view=long&pmid=21345842
open-label phase II study (ACNS0126)
7/6/2004-9/6/2005
======================================
[2] 5/1/2010 – Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
======================================
Prospective Evaluation of Radiotherapy With Concurrent and Adjuvant Temozolomide in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
http://www.ncbi.nlm.nih.gov/pubmed/19647954/
Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):113-8. doi: 10.1016/j.ijrobp.2009.04.031. Epub 2009 Aug 3
http://www.ncbi.nlm.nih.gov/m/pubmed/19647954/
International Journal of Radiation Oncology * Biology * Physics
Volume 77, Issue 1 , Pages 113-118, 1 May 2010
http://www.redjournal.org/article/S0360-3016(09)00597-5/abstract
published online 03 August 2009
Department of Radiation Oncology, Tata Memorial Centre, Mumbai, India
Presented at the Eighth Congress of the European Association for Neuro-Oncology, Barcelona, Spain, September 12–14, 2008
3/2005-11/2006
======================================
[3] 2/2008 – children with diffuse intrinsic brain stem glioma
======================================
Research Article
Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: A Children’s Oncology Group phase II study
http://www.ncbi.nlm.nih.gov/pubmed/17278121/
Pediatr Blood Cancer. 2008 Feb;50(2):227-30
http://www.ncbi.nlm.nih.gov/m/pubmed/17278121/
Pediatr Blood Cancer 2008;50:227–230
http://onlinelibrary.wiley.com/doi/10.1002/pbc.21154/abstract
Pediatric Blood & Cancer
Volume 50, Issue 2, pages 227–230, February 2008
http://onlinelibrary.wiley.com/doi/10.1002/pbc.21154/abstract;jsessionid=1C9E44F96D6558468F0D7EB45D50FE23.d04t03
Pediatric Blood & Cancer
Volume 50, Issue 2, Article first published online: 2 FEB 2007
http://onlinelibrary.wiley.com/doi/10.1002/pbc.21154/full
The Pediatric Oncology Group (POG, now part of the Children’s Oncology Group)
http://onlinelibrary.wiley.com/doi/10.1002/pbc.21154/pdf
DOI 10.1002/pbc.21154
http://radonc.ucsd.edu/patient-info/treatment-options/cancer-types/pediatric-cancers/Documents/Pediatric-Paper-04.pdf
University of Rochester Medical Center, Rochester, New York, USA
======================================
[4] 1/1/2005 – newly diagnosed diffuse brainstem glioma in children
======================================
Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children:
results of a multiinstitutional study (SJHG-98)
http://www.ncbi.nlm.nih.gov/pubmed/15565574
Cancer. 2005 Jan 1;103(1):133-9.
http://www.ncbi.nlm.nih.gov/m/pubmed/15565574
Cancer 103, 133-139
http://onlinelibrary.wiley.com/doi/10.1002/cncr.20741/abstract;jsessionid=6717837591CCC8FCBD8E46163808E221.d03t01
Cancer
Volume 103, Issue 1, pages 133–139, 1 January 2005
http://onlinelibrary.wiley.com/doi/10.1002/cncr.20741/full
Article first published online: 24 NOV 2004
References:
http://onlinelibrary.wiley.com/doi/10.1002/cncr.20741/references
Cited By:
http://onlinelibrary.wiley.com/doi/10.1002/cncr.20741/citedby
DOI: 10.1002/cncr.20741
Department of Hematology-Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA
======================================
[5] .10/21/2002 – paediatric pontine glioma
======================================
Treatment of paediatric pontine glioma with oral trophosphamide and etoposide
http://www.ncbi.nlm.nih.gov/pubmed/12434281/
Br J Cancer. 2002 Oct 21;87(9):945-9
http://www.ncbi.nlm.nih.gov/m/pubmed/12434281/
British Journal of Cancer (2002) 87, 945–949. doi:10.1038/sj.bjc.6600552
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364312/
Published online 21 October 2002
http://www.nature.com/bjc/journal/v87/n9/full/6600552a.html
St. Hedwigs Klinik, Hämato/Onkologie, Steinmetzstr. 1–3, Regensburg, Germany
http://www.nature.com/bjc/journal/v87/n9/pdf/6600552a.pdf
======================================
[6] .9/15/1999 – brainstem gliomas
======================================
A Phase I/II study of carboplatin combined with hyperfractionated radiotherapy for
brainstem gliomas

http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0142(19990915)86:6%3C1064::AID-CNCR24%3E3.0.CO;2-1/full
Cancer 1999;86:1064–9
1999 American Cancer Society
Cancer
Volume 86, Issue 6, pages 1064–1069, 15 September 1999
Article first published online: 20 NOV 2000
DOI: 10.1002/(SICI)1097-0142(19990915)86:63.0.CO;2-1
======================================
[7] 3/15/1999 children with newly diagnosed diffuse intrinsic brainstem tumors
======================================
There is no role for hyperfractionated radiotherapy in the management of
children with newly diagnosed diffuse intrinsic brainstem tumors
: results of a Pediatric Oncology Group phase III trial comparing conventional vs. hyperfractionated radiotherapy
http://www.ncbi.nlm.nih.gov/pubmed/10192340/
Int J Radiat Oncol Biol Phys. 1999 Mar 15;43(5):959-64
http://www.ncbi.nlm.nih.gov/m/pubmed/10192340/
International Journal of Radiation Oncology * Biology * Physics
Volume 43, Issue 5 , Pages 959-964, 15 March 1999
http://www.redjournal.org/article/S0360-3016(98)00501-X/abstract
Department of Radiation Oncology, Mount Sinai Medical Center, New York, NY 10029-6574, USA
======================================
[8] 1/1998 – children with newly diagnosed diffuse pontine gliomas
======================================
Carboplatin and etoposide with hyperfractionated radiotherapy in children with newly diagnosed diffuse pontine gliomas: a phase I/II study
http://www.ncbi.nlm.nih.gov/pubmed/9371386/
Med Pediatr Oncol. 1998 Jan;30(1):28-33
http://www.ncbi.nlm.nih.gov/m/pubmed/9371386/
Medical and Pediatric Oncology
Volume 30, Issue 1, pages 28–33, January 1998
http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1096-911X(199801)30:13.0.CO;2-2/abstract;jsessionid=94E4BFEF2606B89ADDD9682528353D47.d03t02
Article first published online: 7 DEC 1998
http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1096-911X(199801)30:13.0.CO;2-2/pdf
DOI: 10.1002/(SICI)1096-911X(199801)30:13.0.CO;2-2
Department of Hematology-Oncology, St. Jude Children’s Research Hospital, University of Tennessee, Memphis, USA
Pediatric Oncology
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[9] .9/15/1994 – children with brain stem gliomas
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Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A Childrens Cancer Group Phase I/II Trial
http://www.ncbi.nlm.nih.gov/pubmed/8082086/
Cancer. 1994 Sep 15;74(6):1827-34
http://www.ncbi.nlm.nih.gov/m/pubmed/8082086/
Department of Neurology, Children’s National Medical Center, Washington, DC
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The Burzynski Skeptics:
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https://stanislawrajmundburzynski.wordpress.com/2013/08/18/the-burzynski-skeptics/
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Perfessor Robert J. (Bob) Blaskiewicz Blatherskitewicz:
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https://stanislawrajmundburzynski.wordpress.com/2013/07/31/the-burzynski-b-s-app/
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Bob Blaskiewicz (Blatherskitewicz), Faux Skeptic Exposed!:
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https://stanislawrajmundburzynski.wordpress.com/2013/06/07/bob-blaskiewicz-blatherskitewicz-faux-skeptic-exposed/
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Critiquing the #SkepticCanary: “The Skeptics™” (SkeptiCowards©) Bob Blatherskitewicz and the so-called, “self-proclaimed” “CANCER RESEARCHER”:
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https://stanislawrajmundburzynski.wordpress.com/2013/06/03/critiquing-the-skepticcanary-the-skeptics-skepticowards-bob-blatherskitewicz-and-the-so-called-self-proclaimed-cancer-researcher/
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Critiquing Bob Blaskiewicz (#Burzynski Cancer is Serious Business, Part II):
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https://stanislawrajmundburzynski.wordpress.com/2013/03/26/critiquing-bob-blaskiewicz-burzynski-cancer-is-serious-business-part-ii/
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My Critique of Bob Blaskiewicz (Colorado Public Television – PBS CPT12):
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https://stanislawrajmundburzynski.wordpress.com/2013/03/26/my-critique-of-bob-blaskiewicz-colorado-public-television-pbs-cpt12/
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“The Skeptics” (Burzynski: Cancer is Serious Business, Part II):
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https://stanislawrajmundburzynski.wordpress.com/2013/03/24/the-skeptics/
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