Critiquing: Watford Observer – ‘He said he hoped to cure my daughter’

6/7/2013 the Watford Observer published this article By Kathryn Snowdon [1]

“The mother of Luna Petagine has cast doubt on the expensive treatment the family sought in America during the Oxhey girl’s four-year battle with cancer
Expensive treatment,” based on what objective criteria ? [2]
BBC Panorama this week aired an investigation into Doctor Stanislaw Burzynski’s cancer clinic in Texas, where hundreds of children – normally terminally ill – go and seek treatment”

“Luna, who was five-years-old when she died last year, was a patient at The Burzynski Clinic after her parents were told the physician could cure their daughter, despite Great Ormond Street Hospital doctors saying little more could be done for her”
Why the conflicting statements ?

a) “her parents were told the physician could cure their daughter”

b) “The NHS are telling me my daughter’s going to die and this man is telling me that he thinks he can cure her.”

c) “He said he hoped to cure my daughter

d) “The plan was to try and cure Luna.”
Luna’s mother, Lucy Petagine, of Raglan Gardens, said there was no doubt in her mind she was going to send her daughter to Dr Burzynski

“Mrs Petagine said:”

“Of course I’m going to go with him

If anyone had knocked on my door and said

‘here if you try this it will work’

“then yeah I would have tried it because I was in desperation”

“The NHS are telling me my daughter’s going to die and this man is telling me that he thinks he can cure her.”

“Mrs Petagine added:”

“It was all about hope

He said he hoped to cure my daughter

The plan was to try and cure Luna.”

“In order to finance the treatment, which the family believed could be life-saving, more than £100,000 was raised and in September 2011 they travelled to America”

“However, Mrs Petagine said the treatment at The Burzynski Clinic was actually killing her daughter

“She added:”

The treatment was – what was happening – was actually killing Luna because it put this pressure on her brain stem.”
Why did Mrs Petagine say that “the treatment at The Burzynski Clinic”“was actually killing Luna” ?

Did someone tell her this, or was this her personal opinion ?

We know from Burzynski’s 3/2004 publication that:

“The reason for 50% Progressive Disease (PD) in studies is long dose-escalation process, which extends to more than a month’s time period, before the optimal dosage is reached” [3]
“In response to Panorama’s questioning and claims that he was merely selling hope to vulnerable families, Dr Burzynski said:”

“Can you imagine that the US government… they would allow me to be here if I just sell hope?”
Isn’t every cancer treatment “selling hope to vulnerable families”?

Isn’t every cancer clinical trial “selling hope to vulnerable families” ?
“The treatment has not been approved by the American Food and Drug Administration (FDA)
12/2008 – Burzynski’s publication advised:

“In 2004 the FDA granted orphan drug designation for antineoplastons A10 and AS2-1 for the treatment of brainstem glioma” [4]

9/2012“The FDA granted Orphan Drug designation for Antineoplastons A10 and AS2-1 for the treatment of gliomas, in 2009″ [5]
“A month into Luna’s therapy, an MRI revealed the tumour had grown, pressing on Luna’s brain stem and causing her breathing problems and facial palsy”

Mrs Petagine said:”

“They said the tumour’s grown and we were like ‘how could it have grown this quickly, this doesn’t make sense’.”
What does Mrs Petagine mean when she said:

‘how could it have grown this quickly, this doesn’t make sense’ ?

We know from [3] above, that the tumor is likely to grow before the medicine has reached it’s optimal dosage, and the tumor starts to decrease in size
Luna had to be admitted to intensive care in Texas Children’s Hospital

Mrs Petagine said:”

Texas Children’s hate The Burzynski Clinic

“They said they have to clean up all his mess”

“The second you walk in the door they look at your child and they did actually say to us ‘are you a Burzynski family?’”
If Texas Children’s actually does that with every child patient that comes in the door, that would be a really stupid bias to foist on some unsuspecting parent
“Luna died in August last year”
Unfortunately, the article does not tell the reader what happened ?

Was Luna taken off of antineoplaston therapy?

Or was she still on the treatment when she unfortunately passed ?
[1] – 9:50am Friday 7th June 2013, By Kathryn Snowdon
[2] – 9/22/2013 – Critiquing Wikipedia: Burzynski Clinic – 2013 BBC documentary, Curing cancer or ‘selling hope’ to the vulnerable?
[3] – Review Articles on Clinical Trials:

1. 3/2004 – The Present State of Antineoplaston Research
Integrative Cancer Therapies 2004;3:47-58
Volume 3, No. 1, March 2004

DOI: 10.1177/1534735-403261964

Volume 3 Number 1.March.2004

Pg. 50

Click to access 994.pdf

[4] – 12/2008 – Patil, S., Burzynski, S., Chittur, S., Mrowczynski, E., Grela, K. The ingredients of antineoplaston AS2-1 down-regulate glycolysis pathways in glioblastoma cells. Neuro-Oncology 2008; 10:1148

Volume 10 Issue 6.December.2008

Click to access 7897.pdf

[5] – 9/2012 – Patil, S., Burzynski S.R., Mrowczynski, E., Grela, K. P.003. Phenylacetylglutaminate in combination with Phenylbutyrate effectively inhibits growth of brain tumor cell In Vitro. Neuro-Oncology 2012;14(Suppl. 3):iii16

Volume 14 Supplement 3 September 2012

Click to access 9291.pdf