[1] – Quackwatch has this article which claims, in part:
“Tracing the biochemistry involved in Burzynski’s synthesis of antineoplastons shows that the substances are without value for cancer treatment”
“Burzynski has never demonstrated that A-2.1 (PA) or “soluble A-10″ (PA and PAG) are effective against cancer or that tumor cells from patients treated with these antineoplastons have been “normalized.””
“Tests of antineoplastons at the National Cancer Institute have never been positive”
“The drug company Sigma-Tau Pharmaceuticals could not duplicate Burzynski’s claims for AS-2.1 and A-10“
“The Japanese National Cancer Institute has reported that antineoplastons did not work in their studies”
“These facts indicate to me that Burzynski’s claims that his “antineoplastons” are effective against cancer are not credible”
About the Author
Dr. Green (1925-2007) was a biochemist who did cancer research at Memorial Sloan-Kettering Cancer Center for 23 years
He consulted on scientific methodology and had a special interest in unproven methods
This article was adapted from his presentation at the American Association for Clinical Chemistry Symposium in Atlanta in July 1997
This page was revised on January 19, 2013
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Interestingly, the above article does NOT provide any specific citation(s), reference(s), or link(s) to support any of these claims
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[2] – 10/4/1991 – Five doctors (3 from the Cancer Therapy Evaluation Branch (CTEP); including the Head of the Quality Assurance and Compliance Section, Regulatory Affairs Branch, Cancer Therapy Evaluation Program, Department of Health &Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, and 2 invited consultants; including one from the National Institutes of Health (NIH) Clinical Center) visited the offices of Dr. Stanislaw R. Burzynski
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[3] – 10/31/1991 – Michael A. Friedman, M.D. Associate Director, Cancer Therapy Evaluation Program (CTEP), Department of Health &Human Services, National Institutes of Health, National Cancer Institute, sent a one page Memorandum to Bruce A. Chabner, M.D., Director, Division of Cancer Treatment, which stated, in part:
“I thought you would be interested in this for several reasons:”
“3. Antineoplastons deserve a closer look”
“It turns out that the agents are well defined, pure chemical entities“
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“The human brain tumor responses are real”
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[4] – 11/15/1991 – Michael J. Hawkins, M.D., Chief, Investigational Drug Branch, Department of Health &Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, sent a 7 page letter to Decision Network, which stated, in part, on page one:
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“It was the opinion of the site visit team that antitumor activity was documented in this best case series … “
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[5] – 12/2/91 – NCI (National Cancer Institute), Decision Network Report on Antineoplastons, states in part, on page 11:
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“The site visit team determined that antitumor activity was documented in this best case series … “
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[6] – CANCER FACTS
National Cancer Institute • National Institutes of Health Department of Health and Human Services, Antineoplastons, pg. 1
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“The reviewers of this series found evidence of antitumor activity … “
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[7] – Page 1 of 6, BlueCross BlueShield of Alabama, Antineoplaston Cancer Therapy, Policy #: 280, Category: Medicine, states, in part, on page 2 of 6:
Key Points:
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“The reviewers of this series found evidence of antitumor activity … “
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[8] – ANTINEOPLASTON THERAPY, HS-183, pg. 2
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“After the reviewers found some evidence of antitumor activity … “
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These facts indicate to me that Quackwatch, and Saul Green’s claims about “antineoplastons”, are “not credible”
Maybe they should have learned how to use the Freedom of Information Act (FOIA)
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REFERENCES:
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[1] – Stanislaw Burzynski and “Antineoplastons”
Saul Green, Ph.D.
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http://www.quackwatch.org/01QuackeryRelatedTopics/Cancer/burzynski1.html
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[6]
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Click to access Antineoplastons.pdf
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[7]
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[8]
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Click to access HS183_Antineoplaston_Therapy.pdf
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