Pete Cohen chats with Richard A. Jaffe, Esq.

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4/2012Pete Cohen chats with Rick Jaffe
(33:59) 11/9/2012
Richard A. Jaffe, Esq.
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How did you meet Dr. Burzynski?

A long time ago in 1988, um, he hired us to represent him in his Medical Board case, so, uh, started working for him then, and then there got to be more and more work, and, uh, at some point it was so much work, it was just easier for me to be down here
So I moved from New York to Texas, mostly just to, to represent him, and my wife was in the oil industry, so, it was a “no brainer” for her to move down here too

And how, were you intrigued by this whole case ?
I mean, did you work out straight away that this guy was genuine, and there was really something here ?

No (laugh)
How do you know, you know ?
At the time we represented, uh, a number of a alternative health practitioners around the country, and we heard a lot about Burzynski, but you don’t really know
I mean, um, um, there are a lot of stories out there
Every doctor seems to have a few patients, uh, that were helped
So initially, I mean, how do you know ?
His operation was larger than most of any, uh, health practitioners, alternative health practitioners in the country, and, uh, seemed a lot more sophisticated, but, uh, it’s not really until you dig in the medical records of the patients that you really see what’s going on
I mean, that’s what you really need
I mean,
It’s not really even, it’s
’cause this whole thing about anecdotal evidence, that everyone has testimony
so every doctor
You know what I mean ?
anybody
Even charlatans have testimony
people
one or two people
or 3 or 4 that’ll come, and say w
they were cured, and maybe, maybe the patients really believe that to be the case, but, um, oftentimes there’s other explanations
Prior treatment, um, the nature of the disease
Sometimes it’s such that their natural, the natural history is not straight linear, um, but after looking at some of the medical records, I mean, you know, I think
it’s just,
uh, anybody would become a believer, and indeed, I mean, government, government doctors have come down here and looked at

some of the records, and they were convinced that, that the treatment was causing remissions in some brain cancer patients

So, I mean, obviously lawyers, I imagine many lawyers all over the world would often take on a case, when they know, possibly the guy isn’t telling the truth, but they can see there’s still a story, and they, they, they, they, uh, represent that person, but for you, I suppose
that when you realized that there really was a story here, did you kind of get, emotionally caught up in this whole thing and think: “Right, th this guy’s got a cure for cancer, and I I need to bring this to, bring him to just, not bring him to justice, but, clear his name
Well, I think with Burzynski, more so than any client I’ve ever represented
He represents a unique constellation of medical services
He’s the only guy in the world doing what he’s doing with antineoplastons and now with this treatment, so, it’s really different
Uh, you know, with Burzynski, most of the patients, are in bad shape
They’re either dying, uh, they, or they have a disease for which there is no known cure, you know, like a lot of these brain tumors
So, even from the beginning, what’s different is their are many, many patients back then who were on the treatment, that uh, that felt that without this treatment they were going to die, and so that, that’s much different, than the average, any kind of lawsuit
Right ?
So th th these lawsuits, the Burzynski cases back then and now, uh, these cases matter, in a, in a deeper, and fundamental, and personal way than most anything, well I think that any lawyer does
I mean, any criminal defense lawyer, who defends an individual, is defending that person’s, uh, liberty
Alright ?
Versus incarceration
But here it, it wasn’t so much, or, it wasn’t exclusively about Burzynski, it was really about all these other patients, and they certainly believe they needed him, and, uh, uh, many of them, obviously did
So, so that, that, that’s a whole ‘nother dimension, which typically we lawyers don’t get involved in
So, I mean, it’s a responsibility but also a great privilege to be working on these kinds of cases

You’ve been representing him for how long ?

For a long time
Since 1988, continuously

And can you believe this is still going on ?

Well, you know, uh, it’s, you know, it’s, it’s just ongoing
I mean, until there’s a cure for cancer, for all cancer, either done by acknowledged

or, uh, uh, to be Burzynski’s cure or somebody else’s
I mean, this is ongoing
And I guess the problem is, you know, ultimately, there’s nobody yet
Not even Burzynski has the cure for every cancer or
even every stage, or even ev, every, ev, ev, every person that had cancer
So, because it’s such a tough battle, and because, it doesn’t work on everyone
So you have these open questions
Ah, so, so,
Yeah, I mean, I guess, I, I can’t believe he’s still messing around with these clinical trials
I mean, I think that if the drug didn’t have his name attached to it, it’d probably would have been approved by now
So, and I think, so that, that’s unfortunate, I think, that when you fight the FDA, and even if you win, you know, the F, the repercussions, you know, you know I, you know I
Hopefully the drug will be approved, sometime in the future, but, but who knows ?

So, um, why do you think, why was it, I mean, obviously I came over here as you know, for this case, which is now not going ahead at the moment
Why, why, why is that ?
Wha, what has the judge, said ?

Well, of course, you have to (under)stand, this case involves a different type of treatment
It doesn’t involve antineoplastons,the drug Dr. Burzynski invented, and your friend is receiving, and it involves a new approach to cancer, which is sort of like personalized medicine, where they take a bunch of FDA approved drugs, that have shown some promise, on a particular cancer, but are not, uh, approved for that indication, and based on these early clinical trials showing promising results for genetic testing they give these combinations of FDA approved drugs, off-label to patients, and that’s really what the, this case is about, and, uh, you know I think, I don’t think they, they never had a case
I mean, they never had a case
The, the main allegation, in each, of the 2 patients involved, is that they used this treatment, which wasn’t sufficiently tested, and was non-therapeutic, and whatnot, and we had a, what I would call a dry run
We presented the evidence to the Board, or 2 members of the Board, in both of these cases
In each, in each case, the Board members felt that the treatment, was within the standard of care, given the advanced condition of the patient, or one patient, and given how rare the other patient’s tumor was
So, we had our dry run in each case, and the Board found in our favor on the main charge
They had some technical issues with medical records or whatnot, and, uh, the Board basically said, they took the position, ok, agree to some kind of sanction on these little charges, or, or we’re going to go after you on everything
So, we refused the honor, and, uh, the Board then charged him with the same thing that they already cleared him with, or on, and, and so we had to do, you know, basically the same case again, and, uh, the irony in, is in these 2 cases Burzynski wasn’t even in the country
He was, he was, he was away for, uh, in both, for both cases, when the patientscame
So, uh, the question is how do you hold someone responsible
Even if you own the clinic, for treatment administered and prescribed, by other doctors, and that concept of vicarious liability does not, uh, exist in jurisprudence, and in the law governing professional re, responsibility, anywhere in this country
So, the Board’strying to start that
You know, I think they just got in over their heads, they
Most people just knuckle under
You know, most people don’t, are afraid to go to court, so they’ll sign anything just to, you know, not to go forward, but, you know, Burzynski faced serious stuff
I mean, he set, faced, 5, 10, 15 years in jail
So he wasn’t going to be intimidated, by the Medical Board, and he refused to give in
So when I told the Board at the time, and I told them all along, they have no case, and o on the merits they have no case
We already won, and they have no case now, and, and slowly I think, the Board is starting to understand that

And what sort of a person would you say Dr. Burzynski is ?

Well I think he’s a complicated person
I mean, I think, uh, uh, you know, he, I think like a lot of mavericks; I represent a lot of mavericks around the, uh, uh, country
One of the main characteristics of these guys, is that they have absolute and total certainty, in what they believe in, in what they do, um, and no doubt
Uh, they all think they’re right
They all think that history is going to vindicate them
Now, I’ve represented some people where I personally doubt (laugh) that, uh, uh, that belief, but not in Dr. Burzynski’s case
I mean, I think he’s all, he’s definitely helping people
He’s definitely, uh, uh, uh, making, extending people’s lives, and curing some people that otherwise would have died, and so I think he, and so I think he happens to be right
So, uh, you know, so, but, but he’s a human
He’s got a big ego
He thinks he’s, uh, he thinks he has made an important, contribute to medicine, and he’s not shy about sharing that sentiment
So, uh, I think, and I think that he’s, uh, not American
So he comes with a completely different mentality towards, say, the government
Alright, he grew up in communist Poland, where everyone, where everyone, has to work around, the government, and I think that’s much harder here, and, you know, I think he has expectations that, that he would have a lot more freedom, than it turned out he had, too, and he thought he would not have to deal with the kind of government, uh, rigamarole that you have to deal with in communist, Poland

And, and how do you think it might all pan out for him ?
I mean, I know you don’t have a crystal ball, but if you could look, 5 or 10 years down into the future, and, do you think that he will have got somewhere, to be accepted in the medical (?) of oncology ?

Well, I certainly hope so
I mean, 5, 10 years from now
I mean, I think, at a minimum, what’s going to happen, there will be many, many patients who will be alive, and continue to be alive because of him
Some, will have their lives extended
Some will be cured
Some wi, won’t be cured, and will die
So, I think that’s for sure, going to happen
You know, is there going to be an end to, uh, all this ?
We had a period of maybe 10 years where there was very little action with the Board, but, uh, you know, it’s hard, frankly, I mean, just in, and again my perspective, like I’m in a, like a, a sergeant in the trenches, in trench (laugh) warfare
So, it’s hard for me to see the big picture
I mean, I just keep fighting these battles, and there’s one, after another, after another
So this is really just the latest, and on there’s civil lawsuits, and then there are people on the Internet, and then, you know, there could be more Medical Board investigations
So, lo, look there are a lot of people who don’t like what he’s doing
They think what he’s doing is either unethical or wrong, or shouldn’t be giving drugs, these drugs to people, except under clinical trial conditions, and, you know, he has detractors, and he has a lot of supporters
I mean, uh, mostly amongst the patients he’s cured
So, I don’t know that, that, that is gonna resolve itself
I mean, ultimately, he’s one of the few people in the country, that, or maybe the only person in the country that does what he does, and, it’s not the way medicine is practiced, in this country, typically
Right, and, you know, I think what he does, is, is more, is more patient oriented, in a sense that, once you’ve been told you’re terminal, why should you just get the palliative care that a medical oncologist thinks, you know, they should be given
even though when, no one ever gets cured of chemotherapy, once it’s palliative, once you have stage 4, solid tumor

Mmm

I mean, they give chemotherapy for what they call palliative reasons, which means, not curative
So, this concept of giving, just conventional chemotherapy to make you feel better, extend your life 9 weeks, I mean, y, not everyone wants to do that
Some people want a shot for a real cure, and, you know, based on the evidence with antineoplastons
, I mean, he seems to be giving people that shot, and curing some of the people
So, you, you know, I don’t see how, this thing gets resolved
Up until the time that the
treatment, the
antineoplastons is approved by the FDA and, you know,
it’s, it’s hard to see a clear path, for that, for a lot of reasons, not the least of which is financial
I mean, it takes dozens of 10’s of millions of dollars

Mmm

or 10, 100’s of millions
So, I mean, someone has to finance the clinical trials
The drug companies aren’t interested right now
They’d just as soon, buy a drug that’s been fully tested
So, I mean, the drug company response has not been overwhelming, because, even though this phase 2 phase, have resolved, and, and, uh, they have excellent results, the drug companies want to wait and see
So, uh, it’s, it’s big money
I don’t think there’s any way in the world Dr. Burzynski, himself, can fund phase 3
I mean, he, he funded everything else now, but phase 3 are, is a much bigger stage involving dozens and 100’s of patients, and that’s just within the financial means of any individual

it seems like it’s unlikely that its going to happen right
I mean, even from the point of view of, what, with phase 3 trials, they’ll be with children

with brainstem gliomas, right
and the FDA’s saying they’ve got to have radiation

Yeah I, um,
I unfortunately, I haven’t been involved in that process
I just see the result, and I, I, I just don’t see how any parent agrees to that, you know

I don’t see how any parent agrees to it
I don’t see how clinical investigator, agrees to do it
Um, I don’t know
I got so, I got some questions of the FDA as to, why they forced him into this particular protocol
I mean, I don’t know
I don’t have any facts or evidence, but I, I, just doesn’t make any sense to me

what’s you’re about that ?

I don’t know
I mean, I, it just doesn’t seem to me, that it’s a, that it’s a fair clinical trial that

Mmm

either an investigator would find ethical, or a patient, or a family, would agree to have their patient treat, their, their kid treated under
I mean, it just doesn’t make any sense to me
I mean, it’s worse than
I mean, both phases, both phases, both arms of the study, you get radiation
It’s radiation alone versus radiation with his stuff
So, I mean, it just doesn’t make any sense to me, given, given the clinical, the phase 2 clinical trial results

So just a, so just a few things, like, you know I’m going to talk about big Pharma, and then talk about the FDA

Right

They talk about the many people as if they’re one person, but, you know, they’re obviously a collective group of individuals who work for an organization, right ?

Well, I mean, I think, the concern is, that the FDA now, by statute is, in no small part funded, by the pharmaceutical industry
It’s like “Pay as you go”
So the, the pharmaceutical ind, industry now, pays for, the processing of the clinical trials by the FDA
So, and then you have the whole concept of the revolving door
You have a lot of government officials going into the drink, uh, drug companies
So I think that’s another problem
So, I mean, you know, I think conspiracy is too strong of a word, m, but, you know, I will say, I don’t think the system’s set up, for an individual like Burzynski, to get a drug approved
I, I, I just don’t see
There’s no support for that
I mean, the days
I mean, it’s like, Einstein, you know ?
He sat in a patent office, and, and doodled, and had his little theory
He could never get his, stuff published today, you know ?
Where did he go to school
?
Where was he teaching, you know ?
So Burzynski has a lot of the same problems
They say he doesn’t publish, but, they won’t let him publish
So, uh, or they won’t let him publish , in, in the mainstream journals
So, I, I, I think though, I think the, I think the system, has a strong bias, against a guy with a discovery
So, that’s not quite saying, there’s a conspiracy, but it’s, it’s sort of along the same lines, and, you know, the conspiracy implies some kind of, um, intentionality on the part of one or two, or some small group or coterie of people, and I don’t know, I don’t think that’s really the case
I think what happens is, the institutions are such that, they allow certain things, and disallow certain things
Alright ?
I think that’s just
there’s no
I don’t think there’s any 2, 3, 4, or some, coterie of Rocka, they’re like a Rockefeller conspiracy
People are saying that there are 12 industrials
That they control the world
I mean, I don’t see that happening, but, the whole system is such that, you know, it’s, it’s
I guess what, uh
The, there’s a book by, uh, a, a, Thomas Kuhn, the Structure of Scientific Revolutions, and he talks about, normal science, and how science progresses, in terms of paradigm shifts
So, normal scientific medicine, works, uh, by big institutions doing, studies about combinations of drugs, after drug companies, invent mostly, modifications of existing drugs, and, less commonly, completely new drugs, and, uh, less commonly, different classes of drugs
So, you have a whole, you have a whole pipeline from a drug company, a whole, uh, uh, mechanism of testing, by the universities, funded by the pharmaceutical company, uh, all the pharmaceutical companies, and that, that just doesn’t lend itself, to one guy, sitting someplace in Houston, or wherever, and having a drug, put through that process
That just doesn’t happen
Burzynski is, so far as I can tell, the only person, to ever completed, a phase 2 trials on a drug he invented
I don’t think that’s ever happened, before, and I don’t think it’ll ever happen again

Ah, was it ’98, was it the chairman, uh

Kessler ?

Kessler
I saw, an interview he gave, press, a press conference where he was explaining about, being able to fast-track
The FDA trying to make it possible to fast-track, you know, drugs that have shown, you know, positive, rather than going through all of this sort of clinical trial, and there’s a guy in the, in the press conference who started asking questions about Burzynski

Right

and you could just see quite clearly he was very uncomfortable

Right

asking questions about, uh, about Dr. Burzynski
How do you think someone like him,
would view, someone like Dr. Burzynski ?

Not favorably
I think that, uh,

Do you think they must know ?
Do you think they must, even he, let’s just say, if he were on his own, he, he knows there’s something there
That he’s obviously got something

I,
I don’t know, uh
I think, that, the guys in conventional medicine, because Burzynski came from orthodox medicine
He was at Baylor
He was a researcher at Baylor
So, I think, they’re not going to Burzynski, is that, he didn’t go about it, the way, other physicians would have done it, other scientists would have done it
So normally what would happen, is, uh, uh, I mean, I think the critical, point in his story is that, when he was at Baylor, and his, uh, professor was supporting him, this Unger, left, you know, they had space for him
They wanted him to go in the Oncology, uh, Department, but, they wanted the patent, to his drug, and he wouldn’t do it
So, that would have been the more conventional approach
You give up the patent rights, you become part of the team, then some big institution, uh, uh, shepherds the drug through, and then they find some drug company support, who will split the patent with the university
So, had he done that, uh, you know, I think the drug woulda been approved by now, but, you know, it was his drug
He came to America with it, and he wasn’t going to give it all away
So, I mean, I just think that’s, you know, I mean and that’s, you know, I think he wasn’t expecting that kind of thing in America
Maybe in communist Poland, but not in America
So I think that really, you know, set him down the path of being a, a, an alternative health practitioner

And wha, wha, what was it like for you when, uh, winning, the case, in was it, 199, 3, 1998 ?

’97

1997

Well, you know, there wasn’t just one case
I mean, I mean, it was everyone
I mean, I analogize it to, like whack-a-mole, or whack-a-rat, you know
You have, like a rat come out of, of a hole, and you bang him, and one comes out of this hole, and all of a sudden you’ve got 2, and then 3, and, so, you know, during the early ’90’s, I mean, I mean, there were 3 grand juries, uh, we had the Medical Board action, which went to hearing in ’93
The Texas Department of Health sued him in ’92
Half a dozen insurance companies had sued, uh, uh, sued him for, for some, for Racketeering
Uh, Texas Air Quality Department went after him
I’m trying to think who else
So, all of this happened, over the course of 3, or 4, or 5 years, and it was just, continuous, and so, one agency would, would get active, and then, they get beaten down
Then somebody else would come, uh, come up, and surface, and indeed, I mean, you know, it, you know, some of them flat out said they were waiting to see what happened, with this oth, wha, what happened with this other agency, and they weren’t gonna do anything, and then when they got tired, they decided, that this new agency had to do something
So, I mean, that was flat out, what happened
So, yeah, I mean, it culminated in the criminal case, I suppose, but even there it was up and down
I mean, the judge ordered, uh, ordered, prohibited him from giving the treatment to anybody else, because the Texas Medical Board case, ultimately went against us, and then we had to go Congress, and Congress forced the FDA to put all his patients on clinical trials which made the Medical B, Board case moot, and then we won the criminal case
So, after we won the criminal case in, uh, ’97, things got quiet for a little bit
So that, that, that was good
I mean, it was quiet
I mean, relatively quiet, and then, uh, lately in the last couple years it’s been very active again

So the worst case scenario would have been
What would have been the worst case scenario ?

For when ?

And this, this
What could have happened this week if the case had gone ahead ?

Well, the worst case scenario would be, there would be a finding, that, that it’s a depart, it’s a departure from the standard of care to use, uh, off-label drugs, that haven’t been approved by the
FDA for an indicated use, and you can’t use the combination of the drugs until someone gives the stamp of approval saying that their safe and effective, which means, you know, you couldn’t, it couldn’t, you couldn’t give the treatment anymore to patients
So you have 100’s of patients that are on this multi-agent gene-targeted therapy, and ultimately that form of treatment is only available at the Burzynski Clinic
I mean, I don’t think that even clinical trials
Burzynski, depending on how you look at it, he’s a few years ahead of, of, uh, well, even the clinical trials
I mean, they’re some clinical trials now on different kinds of cancer where they’re doing 1, 2, or 3 agents
He’ll use 4 or 5, albeit, lesser dosages
So he’s treated 1,000’s of patients like that, but there’s no place else in the world where people can get, the treatment
So it’s kinda the same thing as back in the ’90’s
We have people on drugs, uh, which are unavailable, uh, and, only available through Burzynski
So, if he couldn’t give them, to people, then they wouldn’t get ’em, and, they’re terminal, and, they’re doing well
I mean, or they’re not going to do as well, or they’re going to die
So, it’s, I guess it, it’s sort of the same thing here, ah, uh, only, uh, the irony is all these drugs are, approved by the FDA, and most cancer patients get off-label, uh, drugs
Drugs off-label
So that’s, very common in cancer
It’s just that not common with the drug used on these patients, and in the combinations used

So, this finally
Whe, when you’ve, uh, won these cases, I mean, there must be, it must be good, right ?
It must be good feeling

I had a good feeling last week
I mean, I mean, you know, or I’ve been working non-stop, for months, every day
I mean, there’s no day off in this kind of stuff
It’s just constant
It’s just, his war
There’s always something to do, and then I’m a solo practitioner
So, when the judge cut the heart of the Board’s case out, I’ve been telling the Board, that they can’t, that they have no basis to, to, to bring charges against him, for several years, since 2010
, 2009, and they’re not listening, and, and, I was pretty sure that once you had a judge look at the case, they would, rule in our favor, you know, but the problem is the Board is, like a law unto themselves, and they think they can do anything, and, uh, they just changed the law, in September
So actually, the Board has no recourse
They, they used to be able to change findings of facts, and conclusions of law, but as of September, 2011, they can no longer do so
So, if the, judges’ ruling s, uh, stands, as I think they will, their only remedy is going to be to appeal to a State District Court, and they’re not used to that, because they, like exercising, uh, complete authority
So, they’re in a new position, and I’m sure this is the 1st case, that they’ve ever, not gotten what they want to, from, from a judge, administrative law judge, and not being able to correct it
So, I mean, that, this is a good ti, completely new experience for the Board, and I feel bad for them (both: laughing)

You, you, you do
As a Board they all sit down, and as a group of people, and talk about Dr. Burzynski, and, and, and work out how they’re gonna bring him down, and then ?

Well, that’s more the conspiracy
I, I, I, I think that, some of the Board members, may know of him
He, but, but, but like I say, he’s appeared in front of these informal settlement conferences, and basically, individually they, I mean, exonerate him, of, of the main charges, but I, I, I think that, you know, when we talk about the Board, the Board other than these a, acting informal settlement conferences, where you have one Board member, and one member of some district disciplinary review committee, we’re not really talking about the Board members, these doctors, and lay members of the Board, we’re talking about the Board staff, and that’s the lawyers and administrators of the Board, and I think, you know, I don’t know
I have some, uh, uh, they need to clean house
I mean, they’re getting some very, very bad legal advice, and I, I just think the legal advice at the top, is, is, is horrible, and, and they need to make some dramatic changes, and I think it would be better for the people of Texas if they, just did some house cleaning with the administrative staff there

And what do you think about the way that, uh, Dr. Burzynski’s been , what’s the word, in England, he’s got a very bad press there

(Alright ?)

and, um, why do you think that is ?

Uh, why, well, I mean, look
I mean, I think, people have opinions
They’re,
they have the right to express opinions
I mean, I think, uh, some of his agents did some things that I think, were not wise, in retrospect
I mean

Mhmm

Uh,

The stuff with the, this kid, this blogger

Yes

(?)

And I think that, uh
I think you have to be very careful, about what you tell people that are expressing opinions, and, you know, I mean, I, I, I think, you know, I think there’s a reason why, lawyers get involved in these cases, and should be involved, and I think what happens is, you know, I think there was a, you know, a well meaning, individual, who just went too far, and I think stirred things up unnecessarily so
You know, I mean, I think someone who had some legal training, acting on Burzynski’s behalf, might not have made some of the, you know, just faux pas that were made
So, I mean, that stirred, some things up, and I think

(?) stirred something up that was already there ?
You know, ’cause, I know, I’ve spoken to so many people in the U.K., and, uh, and you find very few people that have anything positive to say
In fact, a friend of mine who’s a famous doctor on television, when I was here, he was on British television with a little girl, and her father, who were trying to, uh, raise money to, um, come over here and, um, in fact, they couldn’t come anywhere, come, they couldn’t come anyway, because, the, uh, FDA said that this type of brain tumor, she couldn’t be treated anyway
But this doctor, who’s a friend of mine said, uh, Dr. Burzynski is, you know, he’s a medical pioneer
He’s, uh, uh, he said that and then literally, for 2 months, non-stop, I think especially on Twitter, they said that he never should have said this, and the guy is a quack, and he’s a, he’s a fraud, and

So your, your friend got in trouble for saying that he’s a pioneer ?

He didn’t get in trouble, but I mean he got a lot of bad press, for speaking on television with this child next to him, saying that, Dr. Burzynski was, you know, a pioneer, and pioneers often have a hard time, and

Right, right

And, you know, you look at Twitter, uh, you probably don’t
You could be (laugh) and you just see, it’s probably, probably the only, 30, hard, hard core people, who spend, all of their time, trying to

Yeah, I think that’s right
I think it’s a very small group, of people, that are making pretend it’s a big movement
I mean, we’ve looked, at some of the traffic
We’ve analyzed some of the traffic
I don’t even think it’s 30
I think it’s more like, 3, or 4, or 5, that are creating things, and then someone had some friend who’s an actor, who has, you know, 3 million followers, and all
So it’s really a very small group of people, but historically, medical doctors who have stood up for Burzynski, have had negative consequences
We had, someone from the National Cancer Institute, NIH testify, this Nick Patronas, and he got in a lot of trouble for doing that
So, you know, it’s not, it’s, unfortunately, you know, speaking up for Burzynski can have, uh, negative career consequences, or, or just some bad P.R., but that’s, part of being a pioneer
It doesn’t mean that, uh, Burz, I mean, if anything, I mean, it shows, it shows that’s like the medical mafia
Yeah
So, that’s what I call, the church of medical orthodoxy
So, that’s what I call
So

Well I, I think it’s gonna be so interesting when I get this film broadcasted, to see what kind of reaction we get
It, it’s just a story I felt I had to (?)

Where are, where are you going to try and get it ?

I’m going to try and get it
I know people at the BBC

Right

I’ve worked in television
So I’m going to try

Oh really, (?)

I’m gonna try those avenues, but you know what ?
Even if it doesn’t

You have cable
You have some kind of public access ?

Yeah
I’ve, I’ve worked in television for years
So I’ve, I have a very good stab at getting it out there, but if I don’t, I’ll get it broadcasted on the Internet

Oh sure
You do, do a YouTube or something, or do what Merola did as a documentary

(?)

That’s had an amazing impact

Yeah
He’s making a sequel
Eric was just over in England

Oh really ?

I looked after him when he came over

Yeah
He wanted to talk to some of the patients and doctors

Eric, I said, ah, you know, so, we’ll see
But listen, I really appreciate the opportunity to ah

Ok, no problem

really, to be able to talk to you
======================================

======================================
http://www.richardjaffe.com
======================================

Critiquing “The Skeptic” Burzynski Critics: A Film Producer, A Cancer Doctor, And Their Critics (page 11)

onforb.es/11pwse9

http://t.co/vh3cgAR6hW

http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Didymus Judas Thomas, Contributor

Musings on the intersection of Articles, Bias, and Censorship

(The Big 3: A.B.C.)

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

Allen Jones 1 day ago

“Interesting article.”

“Since there are two competing sides here I decided to do a bit of research on Burzynski and his treatment.”

“Success seems to be defined in terms of anecdotes only.”

“And after a continued search there seems to be just as many anecdotes of failures for this treatment.”

“Reading the website “the other Burzynski patient group” that outline all the heart wrenching failures of this treatment was difficult.”

“My conclusion is that this Burzynski is a quack of the lowest level.”

“Shameful!!!”

Allen Jones, I really can NOT adequately express how convincing your “alleged” “bit of research” sounds

Shameful!!!”???

claire G 1 day ago

@Guy Chapman,

(claire G, I really can NOT adequately express how convincing your use of @Guy Chapman is, considering as how “Guy Chapman” has gone by “guychapman” in all 18 of his “erudite” posts)

“It seems to me that actually the FDA are being very fair to Burzynski.”

claire G, please expand on how THIS is “the FDA” “being very fair to Burzynski.”
http://burzynskimovie.com/images/stories/transcript/Documents/BurzynskiTriesToExposeNCI.pdf
“Despite the massive problems with hsi institutional review board, and his abject failure to publish results, they continued to allow him to register new trials.”

claire G, please expand on:

“they continued to allow him to register new trials.”

Exactly WHEN did “they continued to allow him to register new trials” “[d]espite the massive problems with hsi institutional review board”?

Please advise WHERE
“his abject failure to publish results”
was a condition for him “to register new trials.”

“I can’t think of anyone else in that position”.”

“You are so right.”

claire G, “you are so right”

“I can’t think of anyone else in that position”.

Exactly HOW are you going to answer THOSE questions?

“That cracking sound you hear is the FDA bending over backwards to accommodate Burzynski!”

claire G, please explain exactly HOW was the FDA requiring radiation in the phase 3 clinical trial, bending over backwards to accommodate Burzynski!”

Securities and Exchange Commission (SEC) Form 10-Q for the quarterly period ended 5/31/2010:

1/13/2009 Company announced Company had reached an agreement with FDA for Company to move forward with pivotal Phase III clinical trial of combination Antineoplaston therapy plus radiation therapy in patients with newly diagnosed, diffuse, intrinsic brainstem gliomas (DBSG)

Agreement was made under FDA’s Special Protocol Assessment procedure, meaning design and planned analysis of Phase III study is acceptable to support regulatory submission seeking new drug approval

2/1/2010 Company entered into agreement with Cycle Solutions, Inc., dba ResearchPoint to initiate and manage pivotal Phase III clinical trial of combination Antineoplastons A10 and AS2-1 plus radiation therapy (RT) in patients with newly-diagnosed, diffuse, intrinsic brainstem glioma

ResearchPoint is currently conducting feasibility assessment

ResearchPoint has secured interest and commitment from number of sites selected

Upon completion of assessment, randomized, international phase III study will commence”

Study’s objective is to compare overall survival of children with newly-diagnosed DBSG who receive combination Antineoplastons A10 and AS2-1 plus RT versus RT alone

” … only obstacles now are $300 million $s needed to pay for final phase of clinical testing-and FDA requiring children with inoperable brainstem glioma to also undergo radiation
treatment in Phase 3 trials, claiming it would be “unethical” not to do so”

“For all the whining and complaining by Burzynski fans that he’s been so hounded and mistreated by the FDA,”

claire G, please pontificate on THIS:
http://stanislawrajmundburzynski.wiki-site.com/index.php/Main_Page
“I’ve never seen any doctor be allowed that much time and leeway to conduct clinical trials.”

claire G, please advise, what doctor has been allowed the next most “time and leeway to conduct clinical trials,” after Burzynski?

“The big question in many people’s minds is, WHY has Burzynski been given this special treatment?”

claire G, THIS “special treatment?

Antineoplastons: Has the FDA kept its promise to the American people ?:
https://stanislawrajmundburzynski.wordpress.com/2013/03/22/antineoplastons-has-the-fda-kept-its-promise-to-the-american-people
claire G, any questions NOW?

claire G 1 day ago

@AstroturfWatch,

“Antineoplastons are dead.

No more in the USA.

Only the rich, powerful, and the affluent who are “in the know” can get it now (no longer in the USA).”

“Ha!”

“So what you mean then is that nothing has really changed?”

claire G, are you indicating that antineoplastons were NOT available in the USA?

“It was always only either the very wealthy or those who could scrap together the $200,00.00 from donations who could afford antineoplastons.”

claire G, are you indicating that EVERY antineoplaston patient has had to “SCRAP together the $200,00.00”?

“By not publishing his research so that it could be peer reviewed and approved by the FDA Burzynski assured that antineoplastons would not be covered by insurance.”

claire G, please provide your citation(s), reference(s), and / or link(s) which support your:

“By not publishing his research so that it could be peer reviewed and approved by the FDA

Burzynski: What happens when a clinical trial is over?:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-what-happens-when-a-clinical-trial-is-over
National Cancer Institute (NCI) at the National Institutes of Health (NIH)

Cancer Clinical Trials

15. What happens when a clinical trial is over?

“The results of clinical trials are OFTEN published in peer-reviewed scientific journals”

” … WHETHER OR NOT the results are published in a peer-reviewed scientific journal … “
http://m.cancer.gov/topics/factsheets/clinical-trials
This makes it clear that clinical trial results “are OFTEN” published, but sometimes they are “NOT” published “in a peer-reviewed scientific journal”

Burzynski: FAQ: Clinical Trial Results
https://stanislawrajmundburzynski.wordpress.com/2013/04/26/burzynski-faq-clinical-trial-results/
Trial results are not always publicly available, even after a clinical trial ends

U.S. National Library of Medicine National Institutes of Health
http://www.nlm.nih.gov/services/ctresults.html
Burzynski: The FDA’s Drug Review Process: Ensuring Drugs Are Safe and Effective:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-the-fdas-drug-review-process-ensuring-drugs-are-safe-and-effective
“The FDA’s Drug Review Process: Ensuring Drugs Are Safe and Effective”

“[T]he emphasis in Phase 2 is on EFFECTIVENESS”

“This phase aims to obtain PRELIMINARY DATA on whether the drug works in people who have a certain disease or condition”

“Phase 3 studies begin if EVIDENCE of EFFECTIVENESS is shown in Phase 2″

“These studies gather more information about safety and EFFECTIVENESS, studying different populations and different dosages and using the drug in combination with other drugs”
http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm
Burzynski: Declaration of Helsinki:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-declaration-of-helsinki
World Medical Association
http://www.wma.net/en/30publications/10policies/b3
PDF:
http://www.wma.net/en/30publications/10policies/b3/17c.pdf
PDF:
http://www.who.int/bulletin/archives/79(4)373.pdf
National Institutes of Health-HISTORY:
http://history.nih.gov/research/downloads/helsinki.pdf
The Declaration of Helsinki doesn’t indicate WHEN results MUST be published

“If you were sitting on this effective cure for cancers that affect children especially, wouldn’t you want to do whatever it took to make it available to anyone who needed it?”

claire G, ask the FDA

“Isn’t that what an ethical, caring, humanitarian would do?”

claire G, I refer you to the above

Boris Ogon

“You are right now having a live “debate” in front of more than 10,000 people, … “

Peter Lipson, Contributor
Musings on the intersection of science, medicine, and culture

3,932 views

Not so much

Waiting for the 10,000

Peter Lipson, Contributor

Musings on the intersection of science, medicine, and culture

4/19/2013 @ 9:43PM

Peter Lipson: “Speech is best countered by more speech”

Critiquing “The Skeptic” Burzynski Critics: A Film Producer, A Cancer Doctor, And Their Critics (page 10)

onforb.es/11pwse9

http://t.co/vh3cgAR6hW

http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Didymus Judas Thomas, Contributor

Musings on the intersection of Articles, Bias, and Censorship

(The Big 3: A.B.C.)

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

randy hinton 5 days ago

Hey Petey!

“I am ready to sit on a stage with Eric in front of a large crowd and debate this matter with you ANYTIME YOUR READY.”

Petey!, responds:

guychapman 5 days ago

(citing randy hinton 5 days ago)

“WHY DID 230 CHILDREN’S HOSPITAL’S TURN DOWN BURZYNSKI’S PHASE 3 BRAINSTEM GLIOMA TRIAL???”

“The answer is in your own post.”

“They were not convinced the treatment was likely to provide benefit, so why on earth would they subject children to the side effects, infection risk and other known problems with ANP treatment?”

“Unlike Burzynski, they seem to have followed the dictates of the Helsinki declaration.”

guychapman, HOW has Burzynski NOT “followed the dictates of the Helsinki declaration.”?

YOU remind me of this randy hinton comment:

“The hospital’s don’t seem to want to discuss this matter publically.”

And neither do YOU

Sharon Hill 5 days ago

“I am thrilled with this piece.”

“My website, Doubtful News, was also a target of the Burzynski PR machine when they tried to shut down critique and questioning.”

Sharon Hill, I’m “doubtful” your website was worth the trouble

But look on the bright side

You just got free “Pub” in a BIASED CENSORING publication

It’ll be something you can tell the grandkids about

“Very pleased that this part of the story is getting out.”

“The bottom line is, there would be no problems if the clinic just met the same standards expected from all clinics – you follow the federal and state rules and you have evidence to back up your claims.”

“The fact that they have to retaliate the way they do is GOOD evidence they have nothing better to show.”

Sharon Hill, and I see that:

“The fact that you have to retaliate the way you do is GOOD evidence you have nothing better to show.”

As in, NO “citation(s),” NO “reference(s),” and / or NO “link(s)” that support your claims

ovalwooki 5 days ago

“Mr. Burzynski is a fraud, a thief, and a scoundrel.”

ovalwooki, so, like YOU ?

“When people are at their lowest, facing death for themselves or a Loved one, he holds out a lie disguised as hope, takes every dime from them that he can, and in some cases even threatens with lawsuits the very people he’s just ripped off.”

ovalwooki, and we should just take your word for it, because, WHY?

“He threatens innocent people who call him out on his horrible record of successful ” cures “ .”

ovalwooki, WHAT is:

“his horrible record of successful ” cures“ ?

“As far as I know, he’s cured no one, ever, and there is no validity to him or his methods, at all.”

ovalwooki, exactly WHAT does:

“As far as I know”

MEAN ?

“He clearly defines what is most flawed with our system of healthcare, here in America.”

ovalwooki, “clearly defines what is most flawed with our system of” yellow journalism, here in America

randy hinton 5 days ago

“In the 1950’s, Congressman Charles Tobey enlisted Benedict Fitzgerald, an investigator for the Interstate Commerce Commission, to investigate allegations of conspiracy* and monopolistic practices on the part of orthodox medicine.”

“This came about as the result of the son of Senator Tobey who developed cancer and was given less than two years to live by orthodox medicine.”

“That is when he learned of alleged conspiratorial practices on the part of orthodox medicine.”

“The final report clearly indicated there was indeed a conspiracy to monopolize the medical and drug industry and to eliminate alternative options.”

guychapman 3 days ago

“That was 60 years ago.”

“And it was not adopted as generally plausible even then.”

guychapman, so, what has changed since then, because there are definitely still dissimulators like YOU?

“By peerless I mean risible, of course.”

guychapman, so, like your comments, right?

JGC2013 4 days ago

“It seems to me there are nly too possibilities here:”

JGC2013, “nly” ?

“1) Antineoplastons don’t work and after two decades and 60-plus uncompleted and unplublished ‘clinical trials’ Burzinsky is fully aware that there is no evidence antineoplastons showing they are effective at treating advanced cancers, but despite this continues to charge patients to receive antineoplaston treatment for financial gain.”

JGC2013, THAT certainly explains THIS:

Burzynski – The Antineoplaston Randomized Japan Phase II Clinical Trial Study:
https://stanislawrajmundburzynski.wordpress.com/2013/03/28/burzynski-the-antineoplaston-randomized-japan-phase-ii-clinical-trial-study
“In which case he’s a fraud, exploiting desparate people for his own personal gain.”

JGC2013, THAT certainly explains THIS:

“Orac” and the “Oracolytes” Cult of Misinformation:
https://stanislawrajmundburzynski.wordpress.com/2013/04/29/orac-and-the-oracolytes-cult-of-misinformation/
“Or 2) antineoplastons DO work, and Burzinsky does have clinical evidence demonstrating efficacybut rather than publish the results of trials (allowing independent oncologists can first confirm and then adopt antineoplatosn therapy) he’s chosen not to publish in order to maintain a lucrative monopoly on antineoplaston herapy, offering it only to the small subset of cancer patients who afford to pay exorbitant fees to be treated at his clinic and effectively denying millions of other cancer patients access to a cure for their cancer.”

JGC2013, THAT certainly explains THIS:
https://stanislawrajmundburzynski.wordpress.com/2013/05/04/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-9/
“In which case he’s a monster.”

JGC2013, this is NOT a Rob Zombie film

My 1st-hand Review of Orac’s 2nd-Hand Review – Burzynski: Cancer is Serious Business, Part II:
https://stanislawrajmundburzynski.wordpress.com/2013/03/14/my-1st-hand-review-of-oracs-2nd-hand-review-burzynski-cancer-is-serious-business-part-ii
“I personally can’t envision any third posibility. Can anyone else?”

JGC2013,

3). Citation(s), reference(s), and / or link(s)

guychapman 4 days ago

By a curious coincidence, several senior figures in the pharmaceutical industry today gave evidence to the House of Commons Science and Technology Committee on the specific issue of publication before and after the event for clinical trials and data, and discuss the obligations of those conducting trials.
http://www.parliamentlive.tv/Main/Player.aspx?meetingId=13017 (from approx. 18:44 for the directly relevant content)

guychapman, thank you for keeping us appraised of what’s going in the United Kingdom, home to Kings, Queens, Dukes, Dutchesses, Earls, Counts, Countesses, Knights, Dragons, Wizards, etc., and that fairyland you’re living in

"Figures as low as 70-odd percent and as high as 90+ percent."

guychapman, just in case you have NOT noticed, Burzynski is in the United States of America

Travel Tex
http://www.traveltex.com/
“Texas. It’s like a WHOLE OTHER COUNTRY”

Don’t Mess With Texas

“Nobody citing zero percent as being acceptable or desirable, oddly.”

guychapman, YOU have “zero percent” acceptability or desirability, oddly.

AstroturfWatch 4 days ago

“Hey Peter Lipson, while you were at the Cleveland Clinic, did you speak to Dr. Bruce Cohen, the director of Neuro-oncology?”

“Because he is in “Burzynski Part 1″ and was Paul Michaels neuro-oncologist and watch Paul’s brain tumor “disappear” (after previously telling Paul’s parents “this is the worst case we’ve ever seen”.”

“Dr. Cohen is in the “trailer #2″ from Burzynski, Part 1 also.”

“I think Bruce is still there, perhaps you need to give old Bruce Cohen a call ;)”

Bruce H. Cohen, MD Bio – The United Mitochondrial Disease Foundation
http://www.umdf.org/site/c.8qKOJ0MvF7LUG/b.8047243/k.612C/Bruce_H_Cohen_MD_Bio.htm
Dr. Cohen joined Cleveland Clinic’s department of Neurology, in Cleveland, Ohio , in 1989

guychapman 3 days ago

“You don’t get it do you?”

“Science does not work by assuming that single voices in the wilderness somehow counter the consensus view.”

“The consensus of informed opinion is that Burzynski’s treatment is unproven and not terribly likely to become proven, not least because his science appears incompetent.”

guychapman, are you indicating that Dr. Cohen is NOT competent, and misdiagnosed his patient?

Boris Ogon

“You are right now having a live “debate” in front of more than 10,000 people, … “

3,932 views

Not so much

Waiting for the 10,000

| 4/19/2013 @ 9:43PM

Peter Lipson: “Speech is best countered by more speech”

Forbes Learns a Lesson, but Not the Right One: Censorship and Bias re: A Film Producer, A Cancer Doctor, And Their Critics

onforb.es/11pwse9
4/19/2013 @ 9:43PM
http://t.co/vh3cgAR6hW
“Speech is best countered by more speech”
http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Peter Lipson, Contributor

posted an article of a very dubious nature on Forbes (#Forbes), which censored (deleted) comments submitted and screen-captured as having been posted to the article comments section

What did Forbes do to rectify this embarrassing blunder?

Well, they did NOT do what Wikipedia is supposed to do (Do the RIGHT THING), they instead changed their comment acceptance function so that it now does NOT post the comments to the comment section; where they can be screen- saved to show that you submitted them, but now prevents the comments from being posted to the comments section before being reviewed by their censor(s)

I was able to submit comments and screen save them to show I submitted them, but the below, for example, was still censored

Thursday, 5/2/2013-ATTEMPT 1:

Didymus Thomas 30 minutes ago

Mr. Ogon, is this one of the Kurume, Japan case studies you were referring to?
Randomized Phase II Study of Hepatic Arterial Infusion with or without Antineoplastons as Adjuvant Therapy after Hepatectomy for liver Metastases from Colorectal Cancer. Annals of Oncology 2010;21:viii221

Reply

Didymus Thomas 20 minutes ago

Share your comment:
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Didymus Thomas 4 hours ago

Mr. Ogon, you commented:
“One further has to take into account the fact that Scamley has been known to employ idiosyncratic definitions, such as classifying tumor *growth* as “STABLE DISEASE” for “less than 50% reduction in size but no more than 50% increase in size of the tumor mass, lasting for at least twelve weeks.””
FDA has advised:
5/2007 – “Guidance for Industry – Food and Drug Administration”
“Clinical Trial Endpoints for the Approval of Cancer Drugs and Biologics”
“”STABLE DISEASE should not be a component of ORR”
“STABLE DISEASE can reflect the natural history of disease””
(Pg. 10 of 22 = actual pg. 7 of PDF)
“…STABLE DISEASE can be more accurately assessed by TTP or PFS analysis (see below)”
“Also, STABLE DISEASE can be more accurately assessed by TTP or PFS analysis (see below)”
(Pg. 11 of 22 = actual pg. 8 of PDF)
“Time to Progression and Progression-Free Survival”
“TTP – Time to Progression”
“PFS – Progression-Free Survival”
“TTP and PFS have served as primary endpoints for drug approval”
(Pg. 11 of 22 = actual pg. 8 of PDF)
And in addition, the below 2005 non-Burzynski study also uses “STABLE DISEASE?”
Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children
Results of a multiinstitutional study (SJHG-98)

Reply

Didymus Thomas 15 minutes ago

Mr. Chapman, you commented:
” … the failure to publish any usable results from any single trial is grossly unethical”
“ The FDA’s Drug Review Process: Ensuring Drugs Are Safe and Effective” advises:
“[T]he emphasis in Phase 2 is on EFFECTIVENESS”
“This phase aims to obtain PRELIMINARY DATA on whether the drug works in people who have a certain disease or condition”
“Phase 3 studies begin if EVIDENCE of EFFECTIVENESS is shown in Phase 2″
“These studies gather more information about safety and EFFECTIVENESS, studying different populations and different dosages and using the drug in combination with other drugs”

Reply

Didymus Thomas 9 minutes ago

Securities and Exchange Commission (SEC) Form 10-Q for the quarterly period ended 5/31/2010 states:
1/13/2009 Company announced Company had reached an agreement with FDA for Company to move forward with pivotal Phase III clinical trial of combination Antineoplaston therapy plus radiation therapy in patients with newly diagnosed, diffuse, intrinsic brainstem gliomas (DBSG)
Agreement was made under FDA’s Special Protocol Assessment procedure, meaning design and planned analysis of Phase III study is acceptable to support regulatory submission seeking new drug approval
2/1/2010 Company entered into agreement with Cycle Solutions, Inc., dba ResearchPoint to initiate and manage pivotal Phase III clinical trial of combination Antineoplastons A10 and AS2-1 plus radiation therapy (RT) in patients with newly-diagnosed, diffuse, intrinsic brainstem glioma
ResearchPoint is currently conducting feasibility assessment
ResearchPoint has secured interest and commitment from number of sites selected
Upon completion of assessment, randomized, international phase III study will commence
Study’s objective is to compare overall survival of children with newly-diagnosed DBSG who receive combination Antineoplastons A10 and AS2-1 plus RT versus RT alone

Reply

Didymus Thomas 1 minute ago

2003-2006 phase II clinical trial preliminary reports.
The co-authors might include an oncologist:
Drugs R D.
2003;4(2):91-101
2004;5(6):315-26
Integr Cancer Ther.
2005 Jun;4(2):168-77
2006 Mar;5(1):40-7

Friday, 5/3/2013-ATTEMPT 2

(Note how I shortened the comment):

Thank you for submitting your comment:

New comments typically appear within 30 seconds.

Mr. Ogon, 5/2007 – “Guidance for Industry – Food and Drug Administration”
“Clinical Trial Endpoints for the Approval of Cancer Drugs and Biologics”
“Stable disease can reflect the natural history of disease”
“Also, stable disease can be more accurately assessed by TTP or PFS analysis”
“TTP – Time to Progression”
“PFS – Progression-Free Survival”
“TTP and PFS have served as primary endpoints for drug approval”
The below study also uses “stable disease”
Cancer. 2005 Jan 1;103(1):133-9 DOI: 10.1002/cncr.20741

Share your comment:

Saturday, 5/4/2013-ATTEMPT 3

Note how I further shortened the comment):

Thank you for submitting your comment:

New comments typically appear within 30 seconds.

Mr. Ogon, 5/2007 – “Guidance for Industry – Food and Drug Administration, Clinical Trial Endpoints for the Approval of Cancer Drugs and Biologics:” “Stable disease can reflect the natural history of disease”
This study uses “stable disease:”. Cancer. 2005 Jan 1;103(1):133-9 DOI: 10.1002/cncr.20741

Share your comment:
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Forbes posted the 1 below comment out of the above:

Didymus Thomas 3 days ago
Mr. Ogon, is this one of the Kurume, Japan case studies you were referring to?
Randomized Phase II Study of Hepatic Arterial Infusion with or without Antineoplastons as Adjuvant Therapy after Hepatectomy for liver Metastases from Colorectal Cancer. Annals of Oncology 2010;21:viii221

One would hope that Forbes would learn a lesson about censoring individual’s comments, but instead, it seems that they learned a lesson about how to block comments

Here is the BIAS exhibited by Forbes, as far as whose comments they did NOT “censor”

– = “The Skeptic” Critics
+ = Questioning “The Skeptic” Critics

– = 70
+ = 44

+ = 25 more

(pg. 1)

rjblaskiewicz –
guychapman –
Peter Lipson –
rjblaskiewicz –
Vered Yasur –
Angel of Life +
rjblaskiewicz –
guychapman –
guychapman –
Krista Cashatt +

(pg. 2)

Boris Ogon –
junkeeroo +
Boris Ogon –
Sarah
junkeeroo +
junkeeroo +
Boris Ogon –
rjblaskiewicz –
Kendra Sue Too +
Boris Ogon –

(pg. 3)

junkeeroo +
Boris Ogon –
junkeeroo +
guychapman –
FW –
Angel of Life +
rjblaskiewicz –
randy hinton +
Boris Ogon –
rjblaskiewicz –

(pg. 4)

lilady –
Vered Yasur –
junkeeroo +
Tina Patterson +
chriswinter +
guychapman –
Angel of Life +
Boris Ogon –
JGC2013 –
guychapman –

(pg. 5)

lilady –
Angel of Life +
Boris Ogon –
FW –
junkeeroo +
Angel of Life +
Peter Lipson –
Angel of Life +
junkeeroo +
Boris Ogon –

(pg. 6)

Paul Morgan –
guychapman –
JGC2013 –
junkeeroo +
FW –
junkeeroo +
rjblaskiewicz –
FW –
Angel of Life +
Angel of Life +

(pg. 7)

Angel of Life +
FW –
AstroturfWatch +
FW –
junkeeroo +
junkeeroo +
Angel of Life +
Peter Lipson –
AstroturfWatch +
AstroturfWatch +

(pg. 8)

FW –
AstroturfWatch +
Angel of Life +
FW –
FW –
AstroturfWatch +
FW –
rjblaskiewicz –
Boris Ogon –
Boris Ogon –

(pg. 9)

Lynne –
guychapman –
guychapman –
guychapman –
guychapman –
randy hinton +
guychapman –
Boris Ogon –
Boris Ogon –
guychapman –

(pg. 10)

guychapman –
randy hinton +
guychapman –
Sharon Hill –
oval wooki –
randy hinton +
guychapman –
JGC2013 –
guychapman –
AstroturfWatch +

(pg. 11)

guychapman –
Allen Jones –
claire G –
claire G –
randy hinton +
lilady –
Didymus Thomas +
lilady –
Didymus Thomas +
lilady –

(pg. 12)

Didymus Thomas +
lilady –
Didymus Thomas +
Didymus Thomas +
Didymus Thomas +
Didymus Thomas +

“The Skeptic” Critics
TOTAL
18-guychapman –
13-Boris Ogon –
10-FW –
_8-rjblaskiewicz –
_6-lilady –
_3-Peter Lipson –
_3-JGC2013 –
_2-claire G –
_2-Vered Yasur –
_1-Paul Morgan –
_1-Lynne –
_1-Sharon Hill –
_1-oval wooki –
_1-Allen Jones –
70-TOTAL

Questioning “The Skeptic” Critics
TOTAL
12-junkeeroo +
10-Angel of Life +
_7-Didymus Thomas +
_6-AstroturfWatch +
_5-randy hinton +
_1-Krista Cashatt +
_1-Kendra Sue Too +
_1-Tina Patterson +
_1-chriswinter +
44-TOTAL

_1-Sarah (neutral)

“The Skeptic” Critics

guychapman (Guy Chapman, @SceptiGuy, @vGuyUK)
http://www.chapmancentral.co.uk/blahg/
A United Kingdom (UK) blahg

Guy Chapman comments on “Orac’s”:
(http://www.scienceblogs.com/Insolence)

FW (@frozenwarning): I work for the NHS in the UK

frozenwarning comments on “Orac’s”:
(http://www.scienceblogs.com/Insolence)

rjblaskiewicz (Bob Blaskiewicz, R.J. Blaskiewicz, @rjblaskiewicz)
http://www.skepticalhumanities.com

Bob Blaskiewicz comments on “Orac’s”:
(http://www.scienceblogs.com/Insolence)

lilady comments on “Orac’s”:
(http://www.scienceblogs.com/Insolence)

Peter Lipson (@palMD)
http://www.sciencebasedmedicine.org

http://www.sciencebasedmedicine.org/index.php/author/palmd/

http://www.sciencebasedmedicine.org/index.php/editorial-staff/peter-a-lipson-md/

Dr. David H. Gorski (“Orac,” @gorskon, @oracknows, @ScienceBasedMed, #sciencebasedmedicine
runs:
http://www.scienceblogs/Insolence
and is the editor of:
http://www.sciencebasedmedicine.org
and is a “pal” of his “bud:”. Dr. Peter A. Lipson)

Paul Morgan (@drpaulmorgan)

Paul Morgan comments on “Orac’s”:
(http://www.scienceblogs.com/Insolence)

What do all of those “Skeptic” Critics have in common?

Dr. David H. Gorski (“Orac”)

Forbes censors Peter Lipson “Speech is best countered by more speech” article comments:
https://stanislawrajmundburzynski.wordpress.com/2013/04/23/forbes-censors-peter-lipson-speech-is-best-countered-by-more-speech-article-comments/

Boris Ogon (@borisogon)

“You are right now having a live “debate” in front of more than 10,000 people, … “

3,921 views

Not so much

Waiting for the 10,000

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

Peter Lipson:-“Speech is best countered by more speech”

guychapman (Guy Chapman) Critiquing “The Skeptic” Burzynski Critics: A Film Producer, A Cancer Doctor, And Their Critics (page 9)

onforb.es/11pwse9

http://t.co/vh3cgAR6hW

http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Didymus Judas Thomas, Contributor

Musings on the intersection of Articles, Bias, and Censorship

(The Big 3: A.B.C.)

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

guychapman 5 days ago

“Well, this has flushed out i the comments most of what we’ve seen on Twitter and the blogs over the past year or two.”

guychapman, hardly
redd.it/1czvol
Forbes censors Peter Lipson
http://redd.it/1czvol
“Speech is best countered by more
http://www.reddit.com/tb/1czvol
speech” article comments:
https://stanislawrajmundburzynski.wordpress.com/2013/04/23/forbes-censors-peter-lipson-speech-is-best-countered-by-more-speech-article-comments
"On the one side we have the true believers claiming that there is a cure, that it’s being denied, that people would “otherwise die” (begging the question), and asking for “respect” and “decency”"

guychapman, THIS cure ?
http://burzynskimovie.com/images/stories/transcript/Documents/BurzynskiTriesToExposeNCI.pdf
"(as if it is respectful and decent to claim to cure cancer without good evidence)."

guychapman, THIS “good evidence” that you’re “without” ?

Burzynski – The Antineoplaston Randomized Japan Phase II Clinical Trial Study:
https://stanislawrajmundburzynski.wordpress.com/2013/03/28/burzynski-the-antineoplaston-randomized-japan-phase-ii-clinical-trial-study
"On the other side we have one really very simple point: show me the evidence."

guychapman, THIS “good evidence” that you’re “without” ?

The FDA’s Drug Review Process:

Ensuring Drugs Are Safe and Effective

“[T]he emphasis in Phase 2 is on EFFECTIVENESS”

“This phase aims to obtain PRELIMINARY DATA on whether the drug works in people who have a certain disease or condition”

“Phase 3 studies begin if EVIDENCE of EFFECTIVENESS is shown in Phase 2″

“These studies gather more information about safety and EFFECTIVENESS, studying different populations and different dosages and using the drug in combination with other drugs”
http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm
“61 registered human trials, one completed, zero results published, from any of them.”

guychapman, do you mean THIS ?

clinicaltrials . gov does NOT contain the same data as the National Cancer Institute (NCI) at the National Institutes of Health (NIH) cancer . gov web-site:

61 TOTAL
1 – Not Yet Recruiting (Open)(Phase 3)
1 – Closed
2 – Terminated (Withdrawn due to slow enrollment)
7 – Withdrawn (This study has been withdrawn prior to enrollment)
10 – Recruiting (Open)
11 – Open (1 Not Yet Recruiting / 10 Recruiting)
40 – Active, not recruiting (Closed)

The below 1st link: 10 Active (Open):
http://cancer.gov/clinicaltrials/search/results?protocolsearchid=11475951
The below 2nd link: 25 Closed-1st screen / 15 Closed-1 Completed-2nd screen:
http://cancer.gov/clinicaltrials/search/results?protocolsearchid=11476036
NONE of the above are “UNKNOWN” per the above 2 National Cancer Institute (NCI) at the National Institutes of Health (NIH) links:

10 – Recruiting (Open)
11 – Open (1 Not Yet Recruiting / 10 Recruiting)
40 – Active, not recruiting (Closed)

10=Open
11=1 Not Yet Recruiting / 10 Recruiting
40=Closed
61-TOTAL

“The Burzynski fans’ snowstorm of irrelevant, low-grade publications in low impact journals and conference abstracts that aren’t even peer-reviewed, do not address this at all.”

guychapman, are you referring to THIS ?

The “National Cancer Institute (NCI) at the National Institutes of Health (NIH)

Cancer Clinical Trials,

15. What happens when a clinical trial is over?”

“The results of clinical trials are OFTEN published in peer-reviewed scientific journals”

” … WHETHER OR NOT the results are published in a peer-reviewed scientific journal … “
http://m.cancer.gov/topics/factsheets/clinical-trials
This makes it clear that clinical trial results “are OFTEN” published, but sometimes they are “NOT” published “in a peer-reviewed scientific journal”

“The Helsinki Declaration states the obligations of those conducting trials in humans, and getting the results (good or bad) published and available is a core requirement.”

guychapman, WHERE does the Declaration of Helsinki indicate WHEN the final results of human clinical trials MUST be published?

Burzynski: Declaration of Helsinki
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-declaration-of-helsinki
guychapman 5 days ago

“I have some questions for the Burzynski fans.”

guychapman, I have some questions for you

Is it just me, or does it seem like I’m repeating what I already provided HERE?

Critiquing “The Skeptic”
redd.it/1do1ah
Burzynski Critics: A Film
http://redd.it/1do1ah
Producer, A Cancer
http://www.reddit.com/tb/1do1ah
Doctor, And Their Critics (page 9)
https://stanislawrajmundburzynski.wordpress.com/2013/05/04/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-9/
“1. Burzynski’s claims are superficially similar to those of Max Gerson.”

“Gerson’s therapy is known to be ineffective and potentially harmful, but he used patient anecdotes – people sincerely convinced they had undergone a miracle cure – to promote his business.”

“What *objective* mechanism do you propose we use to distinguish between Burzynski and the quack Gerson?”

guychapman, how about the publications and Securities and Exchange (SEC) filings cited on my page 9 critique?

“2. Burzynski has registered 61 clinical trials in humans, completed one and published no useful data from any.”

guychapman, you obviously have a very “fast and loose” definition of “no useful data”

Exactly WHAT is your definition of “no useful data”?

“Can you name any mainstream cancer research operations that have similar rates of failure to compete and publish?”

guychapman, can you name any mainstream publications like Forbes that have similar rates of failure to “compete” and publish my 15+ comments in reply to your 18 comments?

Do you think it was because they knew that I would “rip you a new one” and you would be left there as the proverbial “Emperor (who) has no clothes”?

“3. How many people do you estimate are involved, globally, in the conspiracy to suppress Burzynski’s treatment?”

“My rough guess is a few hundred thousand.”

“Can you give a better estimate with reasons?”

guychapman, let’s start with YOU, guychapman (Guy Chapman, @SceptiGuy, @vGuyUK,
http://www.chapmancentral.co.uk/blahg),
your pals at Wikipedia; Jimmy (Jimbo) Donal Wales,
http://www.jimmywales.com,
(@jimmy_wales – whom you re-twit on Twitter), JzG|Guy, Guy, Anthony (AGK) BASC, Alexbrn, Dave Dial, Drmies, NE Ent, fluffernutter, foxj, jpgordon, Guerillero, Ironholds, John, Lord Sjones23, Tom Morris, Nstrauss, Steve Pereira/SilkTork, Rhode Island Red, Arthur Rubin, Choyoołʼįįhí:Seb az86556 (Seb az86556), Sgerbic, IRWolfie, Six words, Yobol, @RudyHellzapop, @_JosephineJones, @JCmacc1, @Malboury, @DianthusMed, @medTek, @StopBurzynski, @StortSkeptic, Dr. Peter A. Lipson (@palMD), #Forbes censor(s), Dr. David H. Gorski (@gorskon, @oracknows, @ScienceBasedMed, #sciencebasedmedicine,
http://www.scienceblogs.com/Insolence,
http://www.sciencebasedmedicine.org,
The Faux Skeptic Revealed! Bob Blaskiewicz (@rjblaskiewicz, R.J. Blaskiewicz, Blatherskitewicz), C0nc0rdance, Boris Ogon, lilady, JGC2013, claire G, Sharon Hill, Allen Jones, Lynne, @JCmacc1, Paul Morgan (@drpaulmorgan), oval wooki, Vered Yasur, (the Forbes group) and
http://burzynskimovie.com/images/stories/transcript/Documents/BurzynskiTriesToExposeNCI.pdf, etc.

“4. When you talk about Antineoplastons not being chemotherapy, what, in your mind, distinguishes the intravenous administration of one chemical from the intravenous administration of another, other than the fact that it’s Burzynski doing it?”

guychapman, THIS:

“High Dose ANPA chemotherapy IV drip”

“…an unapproved drug, not ordinary “chemotherapy”
https://bulk.resource.org/courts.gov/c/F3/27/27.F3d.153.93-2071.html
“5. When you speak about ANPs not being toxic, what, in your mind, distinguishes the side effects of “non-toxic” ANPs”

“(nausea, hypernatraemia, stroke etc)”

“form the side effects of other, “toxic” drugs?”

guychapman, THIS:

Burzynski: HYPERNATREMIA:
https://stanislawrajmundburzynski.wordpress.com/2013/04/24/burzynski-hypernatremia
FACT: Is “HYPERNATREMIA” listed on the National Cancer Institute (NCI) at the National Institutes of Health (NIH) list as a possible “Adverse Effect” of antineoplastons?:
http://www.cancer.gov/cancertopics/pdq/cam/antineoplastons/healthprofessional/page6
I do NOT see HYPERNATREMIA or STROKE on the list

2/13/2013 – The frequency, cost, and clinical outcomes of HYPERNATREMIA in patients hospitalized to a comprehensive CANCER center
http://www.ncbi.nlm.nih.gov/m/pubmed/23404230
Over 3 month period in 2006 re 3,446 patients, most of the HYPERNATREMIA (90 %) was acquired during hospital stay

Division of Internal Medicine, UT MD Anderson Cancer Center, Houston, TX, USA

Department of General Internal Medicine, University of Texas MD Anderson Cancer Center

Division of Endocrinology, Mayo Clinic

Support Care Cancer. 2013 Feb 13. [Epub ahead of print]

Supportive Care in Cancer
February 2013

DOI
10.1007/s00520-013-1734-6
http://link.springer.com/article/10.1007%2Fs00520-013-1734-6
HYPERNATREMIA in the U.S.:

“HYPERNATREMIA is the most common electrolyte disorder in the United States”

“In some cases, CANCER may cause the condition …”
http://www.nlm.nih.gov/medlineplus/ency/article/000394.htm
“A Burzynski critic has posted:”

“In order to maintain their doses of ANP, patients are required to drink obscene amounts of water every day (some report up to 12 quarts or more)”

“If they fail to do so, they may lapse into unconsciousness or die”

Let’s put this in perspective

FACT: Some sources indicate:

1) A man should drink about
3 liters (101.44 ounces / 3 quarts 5.44 ounces) per day

{12 quarts = 384 ounces = 11.356 liters}

[12 quarts in 24 hours = 1/2 quart or 16 ounces per hour]

2) Extremely healthy kidneys could process about 30 ounces (approx .9 liters) of water in an hour

{30 ounces in 24 hours = 720 ounces}

[720 ounces = 22.5 quarts per day]

3) A person with healthy kidneys could develop water intoxication by drinking about 2 to 3 times what their kidneys can process

So, if extremely healthy kidneys could process about 30 ounces per hour and 12 quarts per day would require one to only drink 16 ounces per hour, that means one is being asked to drink 14 ounces less per hour than what extremely healthy kidneys could process

So even if one drinks more than 16 ounces per hour so that one does not have to be awake hourly, there is still opportunity to do that

Of course, there are certain other factors that might have to be taken into consideration depending on the patient

“6. Burzynski has convinced you that he can cure incurable cancers.”

“What figures has he given you for his five-year survival versus standard of care?”

guychapman, HERE:

2003 – Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma:

a preliminary report
http://www.ncbi.nlm.nih.gov/m/pubmed/12718563
Drugs R D. 2003;4(2):91-101

recurrent diffuse intrinsic brain stem glioma

of all 12 patients
2 years / 33.3% – Survival
2 / 17% – alive and tumour free for over 5 years since initial diagnosis

from the start of treatment
5 years – 1 alive for more than
4 years – 1 alive for more than

2003
Protocol – recurrent diffuse intrinsic brain stem glioma
12 – Patients Accrued
10 – Evaluable Patients
2 / 20% – # and % of Patients Showing Complete Response
3 / 30% – # and % of Patients Showing Partial Response
3 / 30% – # and % of Patients Showing Stable Disease

2004 – Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma :

a preliminary report
http://www.ncbi.nlm.nih.gov/m/pubmed/15563234
Drugs R D. 2004;5(6):315-26

incurable recurrent and progressive multicentric glioma

6 patients were diagnosed with pilocytic astrocytoma

4 with low-grade astrocytoma
1 with astrocytoma grade 2

1 case of visual pathway glioma, a biopsy was not performed due to a dangerous location

1 patient was non-evaluable due to only 4 weeks of ANP and lack of follow-up scans

1 patient who had stable disease discontinued ANP against medical advice and died 4.5 years later

10 patients are alive and well from 2 to >14 years post-diagnosis

2004
Protocol – incurable recurrent and progressive multicentric glioma
12 – Patients Accrued
– Evaluable Patients
33% – % of Patients Showing Complete Response
25% – % of Patients Showing Partial Response
33% – % of Patients Showing Stable Disease
0 / 0% – # and % of Patients Showing Progressive Disease

2005 – Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1
http://www.ncbi.nlm.nih.gov/m/pubmed/15911929
Integr Cancer Ther. 2005 Jun;4(2):168-77

13 children with recurrent disease or high risk

6 (46%) survived more than 5 years

2005
Protocol – recurrent disease or
high risk
– Patients Accrued
– Evaluable Patients
23% – % of Patients Showing Complete Response
8% – % of Patients Showing Partial Response
31% – % of Patients Showing Stable Disease
38% – % of Patients Showing Progressive Disease

2006 – Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma
http://www.ncbi.nlm.nih.gov/m/pubmed/16484713
Integr Cancer Ther. 2006 Mar;5(1):40-7

Brainstem glioma carries the worst prognosis of all malignancies of the brain

Most patients with brainstem glioma fail standard radiation therapy and chemotherapy and do not survive longer than 2 years

Treatment is even more challenging when an inoperable tumor is of high-grade pathology (HBSG)

patients with inoperable tumor of high-grade pathology (HBSG) treated with antineoplastons in 4 phase 2 trials

22% – overall survival at 5 years

17+ years maximum survival for a patient with anaplastic astrocytoma

5+ years for a patient with glioblastoma

5+ year survival in recurrent diffuse intrinsic glioblastomas and anaplastic astrocytomas of the brainstem in a small group of patients

18 – evaluable

2006
Protocol – high-grade pathology (HBSG)
– Patients Accrued
18 – Evaluable Patients
11% – % of Patients Showing Complete Response
11% – % of Patients Showing Partial Response
39% – % of Patients Showing Stable Disease
39% – % of Patients Showing Progressive Disease

2007 – Recent clinical trials in diffuse intrinsic brainstem glioma

Review Article
http://www.cancer-therapy.org/CT/v5/B/HTML/42._Burzynski,_379-390.html
Cancer Therapy Vol 5, 379-390, 2007

(Forbes)

Boris Ogon 1 week ago

(citing AstroturfWatch)

“They refuse to fact check anything. Namely Phase 2 results showing a 25% cure rate for brainstem glioma, never accomplished in medical history—ever.”

“Published plan as day in a ‘internationally peer-reviewed’ article.”

“You mean PMIDs 12718563 and 16484713? (These, at least, are the ones that Merola cites, which I assume is the sum total of your “fact checking.”)”

“Namely Phase 2 results showing a 25% cure rate for brainstem glioma, never accomplished in medical history—ever”

“Notice the chart on page 172 (page 8 of PDF).”

“Find just one, any single cure for this tumor type and you can’t, outside of Antineoplastons FDA sanctioned clinical trials:”
http://www.burzynskiclinic.com/images/stories/Publications/1252.pdf
“The first reference is to Drugs in R&D 4:91 (2003).”

“The second reference is to Integrative Cancer Therapies 4:168 (2005).”

The “chart on page 172 (page 8 of PDF):”
http://www.burzynskiclinic.com/images/stories/Publications/1252.pdf
refers to:

2006 Adis – Pediatr Drugs 2006; 8 (3)

pg 172

Treatments for Astrocytic Tumors

Table II. Treatment of diffuse, intrinsic brainstem glioma in children

Burzynski et al. [88] – Reference
Phase II – Study Type
(no. of pts) – pts = patients
RP (30) – RP = recurrent and progressive tumor – Tumor type
ANP – ANP = antineoplastons A10 and AS2-1 – Treatment – ANP
OS (%) – OS = overall survival
[2y; 5y]
46.7; 30 – Efficacy
MST (mo)
19.9 – MST = median survival time
[% (no. )]
27 (8) – CR – CR = complete response
[% (no. )]
20% (6) – PR – PR = partial response
[% (no. )]
23% (7) – SD – SD = stabile disease
30% (9) – PD = progressive disease

pg 177

88. Burzynski SR, Weaver RA, Janicki T. Long-term survival in phase II studies of antineoplastons A10 and AS2-1 (ANP) in patients with diffuse intrinsic brain stem glioma [abstract]. Neuro-oncol 2004; 6: 386

This is the 2004 publication, NOT 2003

Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma : a preliminary report.
http://www.ncbi.nlm.nih.gov/m/pubmed/15563234
Drugs R D. 2004;5(6):315-26

pg 172

Burzynski et al. [89] – Reference
Phase II – Study Type
(no. of pts) – pts = patients
RPS (10) – RPS = recurrent and progressive tumors in children aged <4y – Tumor type {(66) = most in a study}
ANP – ANP = antineoplastons A10 and AS2-1 – Treatment – ANP
OS (%) – OS = overall survival
[2y; 5y] – Efficacy
60; 20 {46.7 (30) = next best study}
MST (mo)
26.3 – MST = median survival time – {19.9 = next best study}
[% (no. )]
30% (3) – CR = complete response – {27% (8) = next best study}
[% (no. )]
0% (0) – PR = partial response – {56% (1) = next best}
[% (no. )]
40% (4) – SD = stable disease – {44% (25) = best}
[% (no. )]
30% (3) – PD = progressive disease – {23% (13) = best}

(Above, I also provide the best next case to compare to)

pg 177

89. Burzynski SR, Weaver RA, Janicki TJ, et al. Targeted therapy with ANP in children less than 4 years old with inoperable brain stem gliomas [abstract]. Neuro-oncol 2005; 7: 300

Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1.
http://www.ncbi.nlm.nih.gov/m/pubmed/15911929
Integr Cancer Ther. 2005 Jun;4(2):168-77

pg 173

1.4.3 Targeted Therapy

“…multi-targeted therapy with ANP has shown promising results [12;88-91]”

pg 176

90. Burzynski SR, Lewy RI, Weaver RA, et al. Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report. Drugs R D 2003; 4: 91-101

Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report.
http://www.ncbi.nlm.nih.gov/m/pubmed/12718563
Drugs R D. 2003;4(2):91-101

91. Burzynski SR, Weaver RA, Janicki T. et al. Targeted therapy with antineoplastons A10 and AS2-1 (ANP) of high-grade, recurrent and progressive brain stem glioma. Integr Cancer Ther 2006 Mar; 5 (1): 40-7

Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.
http://www.ncbi.nlm.nih.gov/m/pubmed/16484713
Integr Cancer Ther. 2006 Mar;5(1):40-7

30 evaluable patients with recurrent and progressive DBSG

“>40% of patients survived for more than 2 years
30% more than 5 years.”

27% – CR – Complete Response
20% – PR – Partial Response
23% – SD – Stable Disease
30% – PD – Progressive Disease
[12,88]

pg 175

12. Burzynski SR Targeted therapy for brain tumors In: Columbus, F editor. Brain cancer research progress. New York: Nova Science Publishers Inc 2005

pg 173

10 evaluable children
aged <4 years diagnosed with DBSG treated with ANP
youngest 3-month-old infant
[89]

60% – 2-year survival rate
20% – 5-year survival rate
maximum survival more than 7 years

30% – CR – Complete Response
40% – SD – Stable Disease
30% – PD – Progressive Disease
[89]

“The results are compiled in table II.”

pg 174

2.3. Targeted Therapy

Multi-targeted ANP therapy is free from chronic toxicity in children and adults based on the results of numerous clinical studies involving

1652 adults
335 children
[147]

pg 178

147. Burzynski SR. Annual report to the FDA, IND 43,742, 2006

pg 174

Long-term follow-up of children treated with ANP for astrocytomas revealed:
normal development
no cognitive or endocrine deficiencies
normal fertility

>5 years – substantial number of patients tumor free
>17 years – follow-up period for some patients

pg 169

1.1.4. Targeted Therapy

Clinical trials with agents affecting single targets are in progress and the preliminary results of multi-targeted therapy with
antineoplastons (ANP) A10
and
AS2-1 have been reported
[39]

small group of patients with progressive LGA, ANP
60% – CR rate – Complete Response
10% – PR rate – Partial Response
median survival 7 years 9 months
maximum survival of more than 15 years
[39]

LGA = Low-Grade Astrocytomas

Table I. Selected chemotherapy regimens for the treatment of low- grade astrocytoma in children

Burzynski [39] – Reference
Phase II d – d = Preliminary results – Study type
P – P = progressive tumor – Tumor type
(no. of pts) – pts = patients
ANP (10) – ANP = antineoplastons A10 and AS2-1 – Treatment {(78) = most in a study}
OS [%] – OS = overall survival
100% (1 yr) – 90% (3 yr) – Efficacy
93 mo – MST = MST = median survival time – {96 (1 y) next closest}
CR [% (no.)]
60% (6) – CR = complete response {24 (11) next closest}
PR [% (no.)]
10% (1) – PR = partial response {60% (9) best other study}
[% (no.)]
30% (3) – SD = stable disease + MR = minor response {70% (14) best other study}
[% (no.)]
0% (0) – PD = progressive disease {4% (2) next closest}
PFS (%)
90 (1 y) – 90 (3 y) – PFS = progression-free survival {100 (1 y) – 68 (3 y) best other study

(Above, I also provide the best next case to compare to)

pg 176

39. Burzynski SR Clinical application of body epigenetic system: multi-targeted therapy for primary brain tumors. World and Ehrlich Conference on Dosing of Magic Bullets; 2004 Sep 9-11 Nurnberg

Burzynski Clinical Trials (The SEC filings):
https://stanislawrajmundburzynski.wordpress.com/2013/04/11/burzynski-clinical-trials-2
Who has audited these figures?

guychapman, YOU just did

Otherwise, check with the Food and Drug Administration (FDA)

Where are they published?

guychapman, if you have NOT yet figured THAT out…

“7. There are numerous cases where the Burzynski clinic has said a tumour is “dying from the inside”, but where it turns out that it is growing aggressively and suffering necrosis due to outstripping its blood supply; this is usually a precursor to the death of a patient only weeks after being told they were on the way to a cure.”

“How do you account for this repeated error?”

guychapman, WHERE is the documentation?

Boris Ogon

“You are right now having a live “debate” in front of more than 10,000 people, … “

3,919 views

Not so much

Waiting for the 10,000

4/19/2013 @ 9:43PM

Peter Lipson: “Speech is best countered by more speech”

Critiquing “The Skeptic” Burzynski Critics: A Film Producer, A Cancer Doctor, And Their Critics (page 9)

onforb.es/11pwse9

http://t.co/vh3cgAR6hW

http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Didymus Judas Thomas, Contributor

Musings on the intersection of Articles, Bias, and Censorship

(The Big 3: A.B.C.)

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

guychapman 5 days ago

“Ah yes, a 1996 news story based on claims from the clinic.”

guychapman, would you like an opportunity to re-read the below and try again?

junkeeroo 1 week ago

The Washington Times, December 5, 1996:

Doctor’s lifesaving effort could land him in prison
– FDA ignores cancer drug’s success

HOUSTON – Federal prosecutors concede that a cancer doctor they will put on trial here in January for using an innovative but unapproved drug has been “saving lives.”

guychapman, that’s NOT

“…claims from the clinic”

“Bold claims, too. Since then he’s registered 61 clinical trials.”

guychapman, that’s NOT taking into consideration the 72 clinical trials listed on the Securities and Exchange (SEC) filings for

11/25/1997 – Form 10-SB

11/25/1997 – Company sponsoring 72 Phase II clinical trials conducted pursuant to INDs filed with FDA which are currently ongoing

“Where are the published results that back his claims?”

guychapman, HERE:

Burzynski Clinical Trials (The SEC filings):
https://stanislawrajmundburzynski.wordpress.com/2013/04/11/burzynski-clinical-trials-2
guychapman,

“The FDA is a large organisation made up of all kinds of people from clerks to political appointees.”

“No whistleblowers.”

guychapman, how do YOU know?

Surely YOU do NOT expect people to believe something just because you posted it?

Considering your stellar track-record

Where is your independent reliable citation(s), reference(s), and / or link(s)?

“Great conspiracy, really well controlled.”

guychapman, I posted this on your “blahg:”
http://www.chapmancentral.co.uk/blahg
and it was censored (removed)”:

Are you a coward like “Orac,” @gorskon, @oracknows, @ScienceBasedMed, Dr. David H. Gorski?
http://burzynskimovie.com/images/stories/transcript/Documents/BurzynskiTriesToExposeNCI.pdf
“Especially since it necessarily also covers MSKCC, NCI, ACS, CRUK and dozens of other organisations.”

guychapman, where are their reliable independent antineoplaston clinical studies?

“I think the number of people engaged in actively suppressing Burzynski’s miracle cure must be in the hundreds of thousands by now and includes lab technicians, scientists, doctors, regulators, politicians and charities in at least ten countries.”
http://t.co/N7ErbunCV2
guychapman, like THIS?
redd.it/1dk974
Wikipedia, what’s your motivation?
http://redd.it/1dk974
Didymus Judas Thomas’
http://www.reddit.com/tb/1dk974
Hipocritical Oath Blog
https://stanislawrajmundburzynski.wordpress.com/2013/05/02/wikipedia-whats-your-motivation/
“Conspiracies that watertight could give you the world on a plate.”

“I mean, Watergate only involved a handful of people and it was busted almost immediately.”

guychapman, you employ a favorite tactic of critics like you

It seems you are more interested in addressing form (CAPITALIZATION) over substance (the real issues)

Maybe you think that your verbosity (17 posts) will somehow lend credibility to your 3 comments re the Declaration of Helsinki; which does NOT state WHEN human clinical trial results MUST be published, and even though you have repeatedly proclaimed that Burzynski has NOT published the FINAL results of any of his phase 2 clinical trials, you have NOT provided any indication as to WHEN any of those trials were completed so that they can be compared to the 2006 study I cited whose results were published in 2013

You also commented:

“In order to claim that he can cure incurable tumours, he needs to publish high quality clinical trial evidence in peer-reviewed journals,”

yet you do NOT provide any citation, reference, or link that overrides the National Cancer Institute (NCI) at the National Institutes of Health (NIH) information re publication which I have commented on previously.

It is apropo you commented:

“Watergate only involved a handful of people and it was busted almost immediately,”

since President Nixon is credited with starting the

“War on Cancer”

and when Watergate occurred he was told that there was a cancer on the Presidency, but Watergate occurred in 1972 and Nixon didn’t resign until 2 years later, in 1974

It is also appropriate that you mention oncologist David Gorski; who disclosed on social media that Peter Lipson is his “pal”

Did you review Burzynski’s 2003-2006 phase 2 clinical trials preliminary reports to see if any of the authors listed on them is an oncologist?

No?

That’s why your observation that Burzynski (a biochemist) is NOT an oncologist, is irrelevant

Do you have any proof to back up your remarkable claim:

“Against that we have an anonymous shill who takes every word of the Burzynski clinic and its supporters as Revealed Truth”?

No?

That’s because you’re wrong about that just like the other issues I’ve listed above

Mr. Chapman, you attempts at obfuscation of the issues, does not impress

guychapman 5 days ago

You don’t really understand the scientific concept of proof do you?

guychapman, you do NOT really understand the concept of proof, do you?

“That probably explains why you are swallowing Burzynski’s PR hook line and sinker.”

guychapman, NO, unlike you, I actually reviewed things and am able to provide “citations,” “references,” and / or “links”

“In order to claim that he can cure incurable tumours, he needs to publish high quality clinical trial evidence in peer-reviewed journals.”

guychapman, where is your “citation(s),” “reference(s),” and / or “link(s)”?

“He needs to publish his science in a way that others can understand and replicate.”

guychapman, do you mean, like THIS?

Stanislaw Rajmund Burzynski Publications:
https://stanislawrajmundburzynski.wordpress.com/2013/03/16/stanislaw-rajmund-burzynski-publications
Burzynski updates Scientific Publications page:
https://stanislawrajmundburzynski.wordpress.com/2013/03/12/burzynski-updates-scientific-publications-page
Antineoplastons, which were first described by Burzynski:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/antineoplastons-which-were-first-described-by-burzynski
Burzynski: Poland antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-poland-antineoplaston-publications
Burzynski: South Korea antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-south-korea-antineoplaston-publications
Burzynski: Russia antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-russia-antineoplaston-publications
Burzynski: Egypt antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-egypt-antineoplaston-publication
Burzynski: Japan antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/02/19/burzynski-japan
Burzynski: China antineoplaston publications:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-china-antineoplaston-publications
Burzynski and China / Taiwan, ROC:
https://stanislawrajmundburzynski.wordpress.com/2013/02/18/burzynski-china-taiwan-roc
Burzynski and Taiwan, ROC
https://stanislawrajmundburzynski.wordpress.com/2013/02/20/burzynski-taiwan-roc
Burzynski, China, and Dvorit D. Samid:
https://stanislawrajmundburzynski.wordpress.com/2013/02/21/burzynski-china-dvorit-d-samid
Burzynski, Ming-Cheng Liau, and Gi-Ming Lai:
https://stanislawrajmundburzynski.wordpress.com/2013/02/24/burzynski-ming-cheng-liau-gi-ming-lai
Review Article: Antineoplastons:
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/review-article-antineoplastons
Burzynski – The Antineoplaston Randomized Japan Phase II Clinical Trial Study:
https://stanislawrajmundburzynski.wordpress.com/2013/03/28/burzynski-the-antineoplaston-randomized-japan-phase-ii-clinical-trial-study
“The people who need to understand and replicate his work in order to validate it, have been complaining for two decades and more that he has failed to do this.”

guychapman, WHO are “The people”?

“The appeal to conspiracy as an excuse for failure to publish any compelling results is a stable feature of quackery.”

guychapman, YOU ARE part of the “conspiracy” as long as you remain silent and play “dumb” about things like “censorship” and “bias” by Wikipedia; who you are the “apologist” for, and Forbes

“It is not a feature of science as such.”

And neither is your ignorance and inability to provide any citation(s), reference(s), and / or link(s)

guychapman 5 days ago

“That was 1996. Since then he’s registered 60 phase II and eon phase III clinical trials.”

guychapman, “eon”?

“Of these he has completed only one, and has failed to publish any meaningful data from any”

guychapman, where is your in-depth review of these publications?

Drugs in R and D (Drugs in Research and Development)

Drugs R D. 2003;4(2):91-101
http://www.ncbi.nlm.nih.gov/m/pubmed/12718563
Drugs R D. 2004;5(6):315-26
http://www.ncbi.nlm.nih.gov/m/pubmed/15563234
Integrative Cancer Therapies

Integr Cancer Ther. 2005 Jun;4(2):168-77
http://www.ncbi.nlm.nih.gov/m/pubmed/15911929
Integr Cancer Ther. 2006 Mar;5(1):40-7
http://www.ncbi.nlm.nih.gov/m/pubmed/16484713
2007
http://www.cancer-therapy.org/CT/v5/B/HTML/42._Burzynski,_379-390.html

http://www.burzynskiclinic.com/images/stories/Publications/1252.pdf
Critiquing “The Skeptic” Burzynski
redd.it/1dld1j
Critics: A Film Producer, A Cancer
http://redd.it11dld1j
Doctor, And Their Critics (page 8)
http://www.reddit.com/tb/1dld1j

https://stanislawrajmundburzynski.wordpress.com/2013/05/03/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-8/
“(which is in contravention of the Helsinki Protocol governing human trials).”

guychapman, exactly WHERE does the Declaration of Helsinki indicate THAT?

Burzynski: Declaration of Helsinki
https://stanislawrajmundburzynski.wordpress.com/2013/04/25/burzynski-declaration-of-helsinki
“There’s only so much cherry picking you can do.”

guychapman, YOU are the “cherry-picking” King

“The scientific consensus is based on the totality of evidence, or rather in this case the totality of lack of credible evidence.”

guychapman, YOU have NOT provided “credible evidence” of anything, other than your own ignorance:

The dishonesty of Guy Chapman, “The Skeptics” shill
https://stanislawrajmundburzynski.wordpress.com/2013/04/12/the-dishonesty-of-guy-chapman-the-skeptics-shill
guychapman 5 days ago

“PDJT aka “Astroturfwatch” – the irony of a contributor to an astroturfing campaign of the magnitude of Burzynski’s calling skeptics for non-existent astroturfing is amusing.”

guychapman, are you related to, or know this “lilady”?

Orac, a lilady, the
redd.it/1dgqa1
Oracolytes: “The Skeptic” Burzynski Critics: A
http://redd.it/1dgqa1
Film Producer, A Cancer Doctor, And
http://www.reddit.com/tb/1dgqa1
Their Critics:
https://stanislawrajmundburzynski.wordpress.com/2013/05/01/orac-a-lilady-the-oracolytes-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics/
because you sound similar to lilady with your ASSumptions
“You say:”

“Find just one, any single cure for this tumor type and you can’t, outside of Antineoplastons”

guychapman, NO, “you” did NOT say that, since I am NOT “you”

(Forbes)

Didymus Thomas 5 days ago

As former President Ronald Reagan used to say: “Well, there you go again.”

Let me make this perfectly clear and unambiguous as I can.

1. I am NOT Dr. Stanislaw R. Burzynski, I have never worked for him, I have never met him.

2. I am NOT AstroTurfWatch.

3. I am NOT Eric Merola, I have never worked for him, I have never met him.

4. I am NOT Randy Hinton, I have never met him, this article is the first place I have seen his name.

“What you mean is:”

“Find just one, any single cure for this tumor type and you can’t, including Antineoplastons”.

guychapman, when are you going to show whether you are just a coward or not, and PROVE IT?

“Because the point about which you are in denial is that there is no credible evidence that antineoplastons cure anything.”

guychapman, WHAT does this indicate?

The FDA’s Drug Review Process:

Ensuring Drugs Are Safe and Effective

“[T]he emphasis in Phase 2 is on EFFECTIVENESS”

“This phase aims to obtain PRELIMINARY DATA on whether the drug works in people who have a certain disease or condition”

“Phase 3 studies begin if EVIDENCE of EFFECTIVENESS is shown in Phase 2″

“These studies gather more information about safety and EFFECTIVENESS, studying different populations and different dosages and using the drug in combination with other drugs”
http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm
“The endlessly repeated list of low quality publication does not come anywhere close to filling in the gap which ought to be filled by the sixty-one human trials he never published – and all the available evidence indicates he never had any intention of doing so.”

guychapman, WHAT does this indicate?

The “FACT” one should know is that clinicaltrials . gov does NOT contain the same data as the National Cancer Institute (NCI) at the National Institutes of Health (NIH) cancer . gov web-site:

61 TOTAL
1 – Not Yet Recruiting (Open)(Phase 3)
1 – Closed
2 – Terminated (Withdrawn due to slow enrollment)
7 – Withdrawn (This study has been withdrawn prior to enrollment)
10 – Recruiting (Open)
11 – Open (1 Not Yet Recruiting / 10 Recruiting)
40 – Active, not recruiting (Closed)

The below 1st link: 10 Active (Open):
http://cancer.gov/clinicaltrials/search/results?protocolsearchid=11475951
The below 2nd link: 25 Closed-1st screen / 15 Closed-1 Completed-2nd screen:
http://cancer.gov/clinicaltrials/search/results?protocolsearchid=11476036
NONE of the above are “UNKNOWN” per the above 2 National Cancer Institute (NCI) at the National Institutes of Health (NIH) links:

10 – Recruiting (Open)
11 – Open (1 Not Yet Recruiting / 10 Recruiting)
40 – Active, not recruiting (Closed)

10=Open
11=1 Not Yet Recruiting / 10 Recruiting
40=Closed
61-TOTAL

“I don’t think he cares any more about the Helsinki Declaration than he does about any other area of medical ethics.”

guychapman, have you even read the Declaration of Helsinki?

Because if you had, you should be able to indicate which section supports your comment

WHAT was that you were saying about “ethics”?

guychapman 5 days ago

“There’s an interesting parallel with Burzynski here.”

guychapman, there’s an interesting parallel with guychapman, Guy Chapman, @SceptiGuy, @vGuyUK, and the Wikipedia Guys: JzG|Guy and Guy (Help!)
http://t.co/N7ErbunCV2
Wikipedia, what’s your motivation?
redd.it/1dk974
Didymus Judas Thomas’
http://redd.it/1dk974
Hipocritical Oath Blog
http://www.reddit.com/tb/1dk974

https://stanislawrajmundburzynski.wordpress.com/2013/05/02/wikipedia-whats-your-motivation/
“Hoxsey, too, used patient anecdotes and conspiracy theories to sustain his business in the absence of credible evidence for a cure;”

guychapman, thank you for bringing up the issue of:

“absence of credible evidence”

THAT describes you to a “T”

If the shoe fits, wear it

“How do you recommend we should tell the difference between Burzynski and his shill Merola, and the palpable fraud and quack Hoxsey?”

guychapman,

“How do you recommend we should tell the difference between guychapman and his shill Guy Chapman, and the palpable fraud and quack @SceptiGuy / @vGuyUK?”

Guy (Help!)

User:JzG/help|Help!

Trust me, Guy, nothing can help YOU

Boris Ogon 6 days ago

“One interesting element is that Merola himself hasn’t shown up to defend his vexatious DMCA claim, which he has effectively admitted to be meritless by offering to drop it if c0nc0rdance can somehow get the after-the-fact third-party mirrors to not include his E-mail address.”

Boris Ogon, did you entirely ignore the Forbes article?

"A well-known “vlogger” who goes by the handle “C0nc0rdance” reports receiving a DMCA take-down notice from Eric Merola after posting a video critical of Burzynski."

"According to C0nc0rdance:
He objected to my “Fair Use” of a small low-res image of his movie poster.”

“Instead, he drops a post on his Facebook page complaining about this article and mischaracterizing the situation, and 10 minutes later, his adherents appear and start babbling incoherently.”

Boris Ogon, are you referring to THIS?

My review of C0nc0rdance:
redd.it/1dm31j

http://redd.it/1dm31j

http://www.reddit.com/tb/1dm31j

https://stanislawrajmundburzynski.wordpress.com/2013/03/23/my-review-of-c0nc0rdance
Mr. Ogon, I guess you were too lazy to type it, sort of like your “research”?

Burzynski, The Movie shared a link.
about an hour ago

“Wow, and people say the “Skeptics” (aka Astroturf campaign) aren’t powerful and with the system behind them.”

“This is what happens when I take down a YouTube video making false claims against my film and Burzynski as well as illegally using copyrighted images of me without permission within (not to mention publishing my personal emails in which I received countless profanity filled threats also in their YouTube post, and they claim “we” threaten – this is the system fighting back, hard):

“Again, Eric: Section 512(f) isn’t entirely toothless.”

Mr. Ogon, though your “research,” IS

"Send some more bogus takedowns and see what happens."

Mr. Ogon, do you mean THIS?

Dr. Peter A. Lipson (and / or his Censor(s)) is a Coward: Critiquing

“A Film Producer, A Cancer Doctor, And Their Critics:”
https://stanislawrajmundburzynski.wordpress.com/2013/04/26/dr-peter-a-lipson-and-or-his-censors-is-a-coward-critiquing-a-film-producer-a-cancer-doctor-and-their-critics
Dr. Lipson does not opine about the manufactured “hysteria” activities by the Burzynski “Critics,” that occurred on Twitter, YouTube, and other social media sites, which entailed this “fact-challenged” video being “mirrored” (duplicated), a ridiculous amount of times

Boris Ogon 5 days ago

For anyone unfamiliar with the tiresome tactic of “Didymus [Judas] Thomas” of trying to drive signal-to-noise ratio into the ground while being completely unable to respond coherently, this is not a bad place to start:
http://goo.gl/f59kT
He was eventually blocked under the “Competence is Required” policy and started shooting off typically garbled E-mails to Jimmy Wales demanding personal attention.

Mr. Ogon, do you have a relationship with Wikipedia?

Mr. Ogon, did you research THIS on Wikipedia?

[“Remedies may be appealed to, and amended by, Jimbo Wales, …”

([[WP:AP]] Wikipedia:Arbitration/Policy 2.9 Appeal of decisions)]

Mr. Ogon, are you referring to THIS?
http://t.co/N7ErbunCV2
Wikipedia, what’s your motivation?
redd.it/1dk974
Didymus Judas Thomas’
http://redd.it/1dk974

http://www.reddit.com/tb/1dk974
Hipocritical Oath Blog
https://stanislawrajmundburzynski.wordpress.com/2013/05/02/wikipedia-whats-your-motivation/
Mr. Ogon, why don’t you bring your coward self over to my blog where I do NOT censor comments, and let’s find out how you do under Sunshine and Blue Sky?

Boris Ogon

“You are right now having a live “debate” in front of more than 10,000 people, … “

3,907 views

Not so much

Waiting for the 10,000

4/19/2013 @ 9:43PM

Peter Lipson: “Speech is best countered by more speech”

Critiquing “The Skeptic” Burzynski Critics: A Film Producer, A Cancer Doctor, And Their Critics (page 7)

onforb.es/11pwse9

http://t.co/vh3cgAR6hW

http://www.forbes.com/sites/peterlipson/2013/04/19/a-film-producer-a-cancer-doctor-and-their-critics
Didymus Judas Thomas, Contributor

Musings on the intersection of Articles, Bias, and Censorship

(The Big 3: A.B.C.)

4/19/2013 @ 9:43PM

A Film Producer, A Cancer Doctor, And Their Critics

FW 6 days ago

"“Making people undergo clinical trials that hold no promise” – Quite, it is abhorrent that Burzynski does this, and has been doing it for many years."

FW (also known as @frozenwarning), has no proof that anyone is “Making people undergo clinical trials…"

FW continues:

"The FDA was ordered by a scientifically illiterate judge to allow these trials, they had no choice."

FW again makes an unsubstantiated claim

"That the FDA hasn’t stopped this charade is bizarre and inexcusable IMO."

FW, the FDA knows what is going on, unlike you

"Hopefully that will soon happen."

FW, it doesn't look like it:
http://www.china-burzynski.com

http://www.china-burzynski.com/lczl/bingrengushi_135135.html

http://www.china-burzynski.com/lxwm
"There is, as yet, no evidence that he has cured any type of cancer, all we have are a few, mainly historical anecdotes."

FW, have you seen this?

"The FDA's Drug Review Process: Ensuring Drugs Are Safe and Effective" advises:

“[T]he emphasis in Phase 2 is on EFFECTIVENESS”

“This phase aims to obtain PRELIMINARY DATA on whether the drug works in people who have a certain disease or condition”

“Phase 3 studies begin if EVIDENCE of EFFECTIVENESS is shown in Phase 2″

“These studies gather more information about safety and EFFECTIVENESS, studying different populations and different dosages and using the drug in combination with other drugs”
http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm
"By the way, the Phase 3 trial that is registered to Burzynski is not for brain tumours, sorry to disappoint you."

FW, are you saying that you do NOT know what you are writing about?

Because, that is what it looks like to me

Burzynski's Securities and Exchange Commission (SEC) Form 10-Q for the quarterly period ended 5/31/2010 states:

1/13/2009 Company announced Company had reached an agreement with FDA for Company to move forward with pivotal Phase III clinical trial of combination Antineoplaston therapy plus radiation therapy in patients with newly diagnosed, diffuse, intrinsic brainstem gliomas (DBSG)

Agreement was made under FDA’s Special Protocol Assessment procedure, meaning design and planned analysis of Phase III study is acceptable to support regulatory submission seeking new drug approval

2/1/2010 Company entered into agreement with Cycle Solutions, Inc., dba ResearchPoint to initiate and manage pivotal Phase III clinical trial of combination Antineoplastons A10 and AS2-1 plus radiation therapy (RT) in patients with newly-diagnosed, diffuse, intrinsic brainstem glioma

ResearchPoint is currently conducting feasibility assessment

ResearchPoint has secured interest and commitment from number of sites selected

Upon completion of assessment, randomized, international phase III study will commence

Study's objective is to compare overall survival of children with newly-diagnosed DBSG who receive combination Antineoplastons A10 and AS2-1 plus RT versus RT alone

AstroturfWatch 6 days ago

AstroturfWatch, in referring to the author of the article, as well as some of the individuals who posted comments unsupported by any facts, stated:

"And truth and integrity is not an option for them."

"They refuse to fact check anything."

"Anyone can be a journalist nowadays, and “fact-checking” is no longer even on the table."

I proved those statements to be true:

A Film Producer, A Cancer Doctor, And Their Critics:
https://stanislawrajmundburzynski.wordpress.com/2013/04/20/a-film-producer-a-cancer-doctor-and-their-critics
Forbes censors Peter Lipson
http://www.reddit.com/tb/1czvol
“Speech is best countered by more speech” article comments:
https://stanislawrajmundburzynski.wordpress.com/2013/04/23/forbes-censors-peter-lipson-speech-is-best-countered-by-more-speech-article-comments
Dr. Peter A. Lipson (and / or his Censor(s)) is a Coward: Critiquing “A Film Producer, A Cancer Doctor, And Their Critics:"
https://stanislawrajmundburzynski.wordpress.com/2013/04/26/dr-peter-a-lipson-and-or-his-censors-is-a-coward-critiquing-a-film-producer-a-cancer-doctor-and-their-critics
Critiquing “The Skeptic” Burzynski
http://t.co/n1IzlVmZEu

http://reddit.it/1d8am2
Critics: A Film Producer, A Cancer
http://www.reddit.com/tb/1d8am2
Doctor, And Their Critics (page 1)
https://stanislawrajmundburzynski.wordpress.com/2013/04/27/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-1/
Critiquing “The Skeptic” Burzynski
http://reddit.it/1d922h
Critics: A Film Producer, A Cancer
http://www.reddit.com/tb/1d922h
Doctor, And Their Critics (page 2)
https://stanislawrajmundburzynski.wordpress.com/2013/04/28/2-critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-2/
Critiquing “The Skeptic” Burzynski
http://reddit.it/1daz6g
Critics: A Film Producer, A Cancer
http://www.reddit.com/tb/1daz6g
Doctor, And Their Critics (page 3)
https://stanislawrajmundburzynski.wordpress.com/2013/04/29/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-3/
Critiquing “The Skeptic” Burzynski
http://t.co/KnWNoDeWYT

http://reddit.it/1dc3ka
Critics: A Film Producer, A Cancer
http://www.reddit.com/tb/1dc3ka
Doctor, And Their Critics (page 4)
https://stanislawrajmundburzynski.wordpress.com/2013/04/29/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-4/
Critiquing “The Skeptic” Burzynski
http://redd.it/1df875
Critics: A Film Producer, A Cancer
http://www.redd.com/1df875
Doctor, And Their Critics (page 5)
https://stanislawrajmundburzynski.wordpress.com/2013/04/30/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-5/
Critiquing “The Skeptic” Burzynski
http://redd.it/1dg2w9
Critics: A Film Producer, A Cancer
http://wew.redd.com/1dg2w9
Doctor, And Their Critics (page 6)
https://stanislawrajmundburzynski.wordpress.com/2013/04/30/critiquing-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics-page-6/
Critiquing “All truth comes from
http://www.reddit.com/tb/1d9hsa

http://redd.it/1d9hsa
public debate”: A corollary to crank
http://www.reddit.com/tb/1d9hsa
magnetism
https://stanislawrajmundburzynski.wordpress.com/2013/04/28/critiquing-all-truth-comes-from-public-debate-a-corollary-to-crank-magnetism/
IMPORTANT: The live “debate”-A Film Producer, A Cancer Doctor, And Their Critics
https://stanislawrajmundburzynski.wordpress.com/2013/04/27/important-the-live-debate-a-film-producer-a-cancer-doctor-and-their-critics/
IMPORTANT: The live “debate”
http://t.co/KnWNoDeWYT

http://redd.it/1dcja2
that wasn’t-A Film Producer, A
http://www.reddit.com/tb/1dcja2
Cancer Doctor, And Their Critics
https://stanislawrajmundburzynski.wordpress.com/2013/04/29/important-the-live-debate-that-wasnt-a-film-producer-a-cancer-doctor-and-their-critics/
Orac, a lilady, the Oracolytes: “The
http://redd.it/1dgqa1
Skeptic” Burzynski Critics: A Film
http://www.reddit.com/tb/1dgqa1
Producer, A Cancer Doctor, And Their Critics
https://stanislawrajmundburzynski.wordpress.com/2013/05/01/orac-a-lilady-the-oracolytes-the-skeptic-burzynski-critics-a-film-producer-a-cancer-doctor-and-their-critics/
Orac and the Oracolytes
http://redd.it/1defev
“Orac” and the “Oracolytes” Cult of
http://www.redd.com/1defev
Misinformation
https://stanislawrajmundburzynski.wordpress.com/2013/04/29/orac-and-the-oracolytes-cult-of-misinformation/
FW 6 days ago

"So you’d rather get your information from an advertising film than doctors, scientists and researchers."

Dr. Burzynski is a doctor, as is his wife, and if you look at the co-authors on his clinical trial publications, and actually research them, you can determine what they are, as well

"That’s your choice, misguided though it is."

If anyone has been "misguiding" anyone, I would say that it is the author, you, and a number of other individuals who posted comments

"Don’t expect rational people to stop trying to stop Burzynski though."

I do NOT see that you've been "rational"
"What he is doing is unscientific, unethical and immoral."

It's good to learn that you are now judge, jury, and executioner

You remind me of Wikipedia

"Also, the moon landings were real."

FW, it's good to learn that at least you got one thing correct

junkeeroo 6 days ago

FW, I understand that for you “rational and intelligible” means that it corresponds to your biased framework.

Perhaps one day you or your conscience will awaken to reality.

junkeeroo, good point, but I do NOT believe its going to happen any time soon

junkeeroo 6 days ago

re: rather “than doctors, scientists and researchers”

You truly do live in lala-land.

Best of luck to you…

What junkeeroo said

Author

Peter Lipson, Contributor 6 days ago

"There is ZERO published data to support these assertions."

"Please, if you know of something out there other than what you saw in a movie, let us know."

Dr. Lipson, if that's what you call these, oh, well

Burzynski Clinical Trials (The SEC filings)
https://stanislawrajmundburzynski.wordpress.com/2013/04/11/burzynski-clinical-trials-2
Called-out comment

AstroturfWatch 6 days ago

Internationally peer-reviewed published data, page 172
(page 8 of PDF):

Brainstem glioma.

Never been cured in history.

Antineoplastons first ever cures.
http://www.burzynskiclinic.com/images/stories/Publications/1252.pdf
FW 6 days ago

"I have no particular interest int he FDA as I work for the NHS in the UK,which also doesn’t support Burzynski due to the lack of evidence on efficacy and safety, and the dubious practices."

FW, sounds like you could use a little help, just like Dr. Lipson:

Burzynski Clinical Trials (The SEC filings)
https://stanislawrajmundburzynski.wordpress.com/2013/04/11/burzynski-clinical-trials-2
"Merola doesn’t investigate, he is a blind disciple of Burzynski."

FW, from what I can tell, if anyone has proven to be a "blind disciple," it has been YOU

"Not once has he addressed the perfectly valid criticisms."

FW, I said it before and I'll say it again:

It’s a bit hard to address anything when Forbes is censoring (deleting) your comments

"Let’s look at it this way, if Burzynski had a 25% success rate, why has he not published this miraculous data?"

"Yet again, you show that Burzynski supporters do not know what they are reading."

FW, on the subject of people NOT knowing what they are reading, you do NOT appear very knowledgeable, considering your lack of any citation(s), reference(s), and / or links

Boris Ogon

“You are right now having a live “debate” in front of more than 10,000 people, … “

Peter Lipson, Contributor
Musings on the intersection of science, medicine, and culture

3,799 views

Not so much

Waiting for the 10,000

4/19/2013 @ 9:43PM

Peter Lipson: “Speech is best countered by more speech”