Talk to the Hand: The #Fail of Barbara Ann Karmanos Cancer Institute, Barbara Ann Karmanos Cancer Center, Cancer Committee, Barbara Ann Karmanos Cancer Center, Alexander J. Walt Comprehensive Breast Center at the Barbara Ann Karmanos Cancer Center, Breast Cancer Multidisciplinary Team (MDT), Karmanos Cancer Center Michigan Breast Oncology Quality Initiative (MiBOQI) project, Detroit, Michigan, Wayne State University School of Medicine, Graduate Program in Cancer Biology, Detroit, Michigan, Breast Oncology Quality Initiative, University of Michigan, Ann Arbor, Michigan, University of Michigan Medical School, Ann Arbor, Michigan, American College of Surgeons Committee on Cancer (ACS CoC), Breast Cancer Biology Program, Institute for Science in Medicine, The Cancer Institute of New Jersey, UMDNJ (University of Medicine and Dentistry of New Jersey)-Robert Wood Johnson Medical School, New Brunswick, New Jersey, Joint Graduate Program in Cell & Developmental Biology at Rutgers University in Piscataway, New Jersey, MetroHealth Medical Center, University of Chicago, Case Western Reserve University / University Hospitals Case Medical Center, Cleveland, Ohio, American Board of Surgery, American Society of Clinical Oncology, Conquer Cancer Foundation of ASCO and Breast Cancer Research Foundation, St. Peter’s University Hospital, New Brunswick, New Jersey, Lutheran General Hospital, Park Ridge, Illinois, State of Ohio, State of Michigan, and Science-Based Medicine (SBM)

David H. Gorski, M.D., Ph.D., F.A.C.S. is an academic (i.e.: egg-head, paper-pusher, apparatchik) surgical oncologist specializing in breast surgery and oncologic surgery

Gorski is no H.G. Wells

Wells could, at least, tell a convincing lie; as he did in War of the Worlds

Gorski’d likely #fail as his evil half-brother, “H.G. #Fails”, in World War Peed, and probably didn’t think his readers would get the double-entendre’

Gorski is more famouser for pie in the sky

He’ll never be likened to Samuel Langhorne Clemens, or receive a “Mark Twain Award”

He’s an unlicensed Hackademic Quackademic who believes that bad press is good press, any press is good press

Gorski is the “Guy” who felt he was Scroogled by Google, when he and his public relations (P.R.) team; which reside in the ‎hyperthalamus section of his brain, decided on 12/5/2012 to go pure pseudononsense pseudononscience:

Critiquing: Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies [1]

wherein he quoted

Dr Burzynski:

“I published the review article in a peer-reviewed journal almost 20 years ago on the principles of personalized gene-targeted therapy”

======================================
Gorski:

“Curious as to just what the heck Burzynski was talking about here, I searched PubMed for this alleged review article”

“I couldn’t find it on PubMed”

“His only publications from the 1990s had nothing to do with cancer as a “genetic disease” or “personalized gene-targeted cancer therapy” and everything to do with antineoplastons”

“Perhaps Burzynski proposed this “revolutionary”
new idea in a peer-reviewed article that’s not indexed in PubMed, but if he did I couldn’t find it using Google and Google Scholar”

“I was in graduate school 20 years ago, and was taught back then that cancer was primarily a genetic disease.. ”

“There’s a term called “oncogene,” which describes genes that, when either mutated or too much is made, can result in cancer”
======================================

======================================
Gorski would have the reader suspend belief, and believe that he’s not smarter than a fifth-grader; which is entirely plausible

That he could not do a search on the words:

antineoplastons
oncogenes
Burzynski

and find anything whatsoever
======================================

======================================
and that he did not have the cranial capacity to access the Burzynski Clinic web-site’s Scientific Publications page:
======================================

======================================
The United States Food and Drug Administration (FDA) did NOT have any problem finding it
======================================

======================================
Pg. 24

1997 – Burzynski. S.R. Antineoplastons. oncogenes and cancer. Anti-Aging Medical Therapeutics, Vol.1. Klatz RM.
Goldman R. (Ed). Health Quest Publication 1997; Marina del Rey, CA. USA
——————————————————————

Click to access burzynski_fdauntitled_promo_2012.pdf

======================================
This, from a doctor, eager to prove to the world, just how smart he is, because of:
——————————————————————
12/.5/2011 – “positions I hold at an NCI-designated comprehensive cancer center“ [2]
======================================

======================================
12/13/2012 – “positions I hold at an NCI-designated comprehensive cancer center“ [3]
======================================

======================================
3/7/2013 – “my last two jobs have been at NCI-designated comprehensive cancer centers“ [4]
======================================

======================================
11/2/2012 – “Personally having pored over Burzynski’s publications” [5]
======================================

======================================
2/18/2013 – “I’ve read many of Burzynski’s papers” [6]
======================================

======================================
5/8/2013 – “I’ve searched Burzynski’s publications” [7]
======================================

======================================
6/5/2013 – “I do know cancer science” [8]
======================================

======================================
6/10/2013 – “I do know cancer science” [9]
======================================

======================================
6/7/2013 – “Unlike Mr. Merola, I am indeed very concerned with getting my facts correct” [10]
======================================

======================================
The same “Guy” who claimed:

Burzynski never explains which genes are targeted by antineoplastons
======================================

======================================
A statement which I showed to be incorrect, by pointing out at least 18 different Burzynski scientific publications which did what Gorski claimed they did NOT [11-12]
======================================

======================================
When Dr. David H. Gorski said:
——————————————————————
“Personally having pored over Burzynski’s publications”–11/2/2012

“I’ve read many of Burzynski’s papers”–2/18/2013

“I’ve searched Burzynski’s publications”–5/8/2013
——————————————————————
exactly what did he mean by “pored over,” “read,” and “searched” ?

Some Bill Clintonesque definition designed to try and stump anyone who’s not smarter than a fifth-grader ?

(“It depends upon what the meaning of the word ‘is,’ is”)

You don’t have to be smarter than a fifth-grader to understand that if Dr. Gorski actually did what he said he did, that he should have been able to conclude without any hint of doubt, that Burzynski explains which genes are targeted by antineoplastons

Where was your head ?

Was your head in Mississippi ?

Was your head like a hole ?

Or was your head so far up your “Show Me State” pal Robert J. (don’t call me “Bobby”) Bob (I’m not a doctor, I just pretend like I’m one on the otherburzynskipatientgroup (TOBPG) and houstoncancerquack) blatherskite Blatherskitewicz (known liar) Blaskiewicz’s AstroTurf campaign, that you couldn’t see what you were not doing ?

This is a guy who has been funded by:

a) the Department of Defense (DOD)

b) the NIH (National Institutes of Health)

c) the Conquer Cancer Foundation of ASCO

and

d) the Robert Wood Johnson Foundation

and this is the kind of supposed “Science-Based Medicine” (SBM) “results” he produces ?

This guy is proclaimed as:

“a prolific essayist and managing editor of Science-Based Medicine, a highly-respected blog that exposes non-scientific research and practices”

A “highly-respected blog” ?

really ?

Really ??

REALLY ???

You’ve gotta be kiddin’ me !!!

“For the last ten years, he has been a major voice — as himself and pseudonymously — for science-based medicine”

You mean that “Orac” Hack ?

“Dr Gorski also runs an active research laboratory at the Barbara Ann Karmanos Cancer Institute”

Research ?

Is it similar to his “research” which I exposed here?

And yet, after showcasing such “brillianot” research skilz, Tuesday, 7/30/2013, Dr. Gorski was appointed / named program co-director of Michigan Breast Oncology Quality Initiative (MiBOQI); a state-wide initiative to improve the quality of breast cancer care using evidence-based guidelines [13]

He “will be involved in many aspects of the quality initiative”

Let’s hope that one of those aspects is NOT the “research” one

“Dr. Gorski has the breadth and depth of knowledge to effectively lead our very strong Breast Multidisciplinary Team,” said Dr. Bepler

“I have every confidence that Dr. Gorski will continue this very high standard of care.”

Perhaps Dr. Bepler is out-of-touch with reality when it comes to Gorski’s “research” and “standard of care” abilities

I wonder how long it is before his effort at infiltrating evidence-based guidelines with his Science-Based Medicine, raises its ugly hypocritical head ?

During the Holidays, maybe Dr. Gorski will have time to celebrate his promotion with his wife with an evening out, and before he pops the surprise to her about his retirement plans for Castro’s Cuba, he can take her by the hands, stare into her eyes with his big brown eyes; they have to be brown, right (?), because he’s so full of “it,” (?) and tell her these heart-warming words:

Darling, I know, that you know, that what I do brings home the bacon, and so it makes a difference in Michigan

In fact, I wanted to let you know how much of a difference I’m helping to make

1997 thru 2001, African American women breast cancer death rates per 100,000 in Michigan; as reported in the American Cancer Society Cancer Facts & Figures for African Americans, 2005-2006, listed Michigan as the state tied with the 20 most breast cancer cases per 100,000, with 36.2

I’m proud to announce that for the last 2 reporting periods (2011-2014), covering 2003 thru 2009, Michigan is no longer tied with the state with the 20 most cases of breast cancer per 100,000

Michigan is now the state with the 11th most cases of breast cancer in African American women, which rose .5 from 33.8 to 34.3 over the last 2 reporting periods

And that’s not all

African American women breast cancer incidences in Michigan, per 100,000, rose from 119.0, 2000 thru 2004 as reported in the 2007-2008 report, up .4 to 119.4, 2006 thru 2010, as reported 2013-2014

Additionally, African American women breast cancer death rates in Michigan, per 100,000, rose from 33.8 for 2003 thru 2007, as reported for 2011-2012, up .5 to 34.3 for 2006 thru 2010, reported 2013-2014

And furthermore, breast cancer incidences in Michigan, per 100,000, were 119.4 for African American women for 2006 thru 2010, reported 2013-2014, and 118.7 for 2006 thru 2010 for white women, reported 2013-2014

So African American women had .7 more breast cancer incidences than white women

And also, the breast cancer death rates in Michigan, per 100,000, was 34.3 for African American women 2006 thru 2010, reported 2013-2014, 11.5 more than the 22.8 for white women for 2006 thru 2010, as reported 2013-2014

And I thought you’d be very pleased to know that the estimated new breast cancer cases in women in Michigan, rose from 6,120 in 2008, to 8,140 in 2013

An increase of 2,010

And, Michigan went from being the state with the 9th most cases of estimated new breast cancer cases, to the 8th

And as if that were not enough great news for you, the estimated breast cancer deaths in women in Michigan, rose from 1,350 in 2004, to an additional 10 more women, 1,360 in 2013

And just like with the estimated new women breast cancer cases, again, Michigan went from being the state with the 9th most cases of estimated breast cancer deaths, to the 8th

And last, but certainly not least, Michigan cancer death rates dropped from 25.8 in 2008, 1.8 to 24.0 in 2013

However, Michigan went from being the state tied with the 18th most cancer cases per 100,000, to the state tied with the 11th most

But don’t worry honey

If you’re white like me, because you’re in Michigan, the breast cancer incidence for you per 100,000, went from 133.9 for 1998 thru 2002, as reported 2005-2006, down 15.2 to 118.7 for 2006 thru 2010, as reported 2013-2014

And, even better, white death rates in Michigan per 100,000, dropped from 27.3 for 1996 thru 2000, as reported 2003-2004, 4.5 to 22.8 for 2006 thru 2010, as reported 2013-2014

And best of all, sweetie, if you do get breast cancer and you’re white, you have a 9% better 5-year overall survival rate (69% – whites / 60% – African Americans, and for each stage of diagnosis for most cancer sites)

And I’d be remiss if I didn’t point out that life expectancy is lower for African Americans than whites among women (77.2 vs. 80.9 years) (2013-2014)

If that’s not job security for me, I don’t know what is

The mistake that Gorski made is that he did not take into account that this is not the age of Hitler, Stalin, Lenin, Mussolini, etc

In this day and age, people canNOT get away with adopting lying as a part of a strategy, because the NSA is watching, and so are We, the People

Remain calm

Germans subjugated themselves to Hitler, the Soviets, Stalin, Italians, Mussolini, Cubans to Castro, and none of them were worth subjugating oneself to

None of them were worth being put on a pedestal

None of them were greater than you or I

Gorski is NOT the greater good

Gorski has a degree in “B.S.” from the University of Michigan

I do not have a “B.S.” degree

I’m the one NOT full of “B.S.”

Now that sounds like a story ripe for a journalistic investigation

So, I guess that means Bob Blaskiewicz’s fave “journalist,” Liz Szabo, and USA TODAY, are out of the running for this type of “reporting”

But look on the bright side:

“In his new role, he will work with the Samuel Silver, M.D., Ph.D., who is the MiBOQI program director, as well as assistant dean for Research and professor of Internal Medicine/Hematology-Oncology at the University of Michigan Medical School”

Maybe “the Samuel Silver, M.D., Ph.D.” will be GorskGeeks “checks and balances”
======================================
“Our only goal is to promote high standards of science in medicine”
======================================
http://www.sciencebasedmedicine.org/editorial-staff/
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Such risible hyperbole would induce fits of laughter in me if it weren’t such a complete lie
======================================
I’m just glad dad got outta Kellogg country while he could
——————————————————————
P.S.: Per Dr. David H. Gorski, anything which might erroneously be perceived as a lie about Burzynski, is NOT anything wrong, per Wayne State University [14]
======================================

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REFERENCES:
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[1] – 12/5/2012 – Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies
——————————————————————
http://scienceblogs.com/insolence/2012/12/05/arrogance-of-ignorance-about-cancer/
======================================
[2] – 12/5/2011 – “positions I hold at an NCI-designated comprehensive cancer center“
——————————————————————
sciencebasedmedicine . org
——————————————————————
http://www.sciencebasedmedicine.org/stanislaw-burzynskis-personalized-gene-targeted-cancer-therapy/
——————————————————————
[3] – 12/13/2012 – “positions I hold at an NCI-designated comprehensive cancer center“
——————————————————————
scienceblogs . com/Insolence
——————————————————————
http://scienceblogs.com/insolence/2012/12/13/stanislaw-burzynski-personalized-gene-targeted-cancer-therapy-for-dummies/
======================================
[4] – 3/7/2013 – “my last two jobs have been at NCI-designated comprehensive cancer centers“
——————————————————————
National Geographic’s #NatGeo Science Blogs
——————————————————————
http://scienceblogs.com/insolence/2013/03/07/the-cancer-treatment-centers-of-america-cherry-picked/
======================================
[5] – 11/2/2012 – “Personally having pored over Burzynski’s publications”
——————————————————————
scienceblogs / Insolence
——————————————————————
http://scienceblogs.com/insolence/2012/11/02/stanislaw-burzynski-fails-to-save-another-patient/
======================================
[6] – 2/18/2013 – “I’ve read many of Burzynski’s papers”
——————————————————————
Science Based Medicine
——————————————————————
http://www.sciencebasedmedicine.org/stanislaw-burzynskis-cancer-success-stories/
======================================
[7] – 5/8/2013 – “I’ve searched Burzynski’s publications”
——————————————————————
Respectful Insolence
——————————————————————
http://scienceblogs.com/insolence/2013/05/08/eric-merola-and-stanislaw-burzynskis-secret-weapon-against-the-skeptics-fabio-lanzoni-part-2/
======================================
[8] – 6/5/2013 – “I do know cancer science”
——————————————————————
ScienceBlogs
——————————————————————
http://scienceblogs.com/insolence/2013/06/05/odds-and-ends-about-burzynski-clinic/
——————————————————————
[9] – .6/10/2013 – “I do know cancer science”
——————————————————————
#ScienceBasedMed
——————————————————————
http://www.sciencebasedmedicine.org/bbc-panorama-investigates-stanislaw-burzynski/
======================================
[10] – 6/7/2013 – “Unlike Mr. Merola, I am indeed very concerned with getting my facts correct”
——————————————————————
Nat Geo
——————————————————————
http://scienceblogs.com/insolence/2013/06/07/i-want-my-anp/
======================================
[11] – 8/7/2013 – Critiquing: Dr. David H. “Orac” Gorski, M.D., Ph.D, L.I.A.R.:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/07/critiquing-dr-david-h-orac-gorski-m-d-ph-d-l-i-a-r/
======================================
[12] – 9/21/2013 – Critiquing: The Institute of Medicine report on cancer care: Is the system “in crisis”?:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/21/critiquing-the-institute-of-medicine-report-on-cancer-care-is-the-system-in-crisis/
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[13] – .7/30/2013, Tuesday – Karmanos Cancer Center’s Dr. David Gorski appointed program co-director (named co-director) of Michigan Breast Oncology Quality Initiative:
——————————————————————
http://www.karmanos.org/News/Default.aspx?sid=1&nid=359
——————————————————————
http://prognosis.med.wayne.edu/article/dr-gorski-named-codirector-of-michigan-breast-oncology-quality-initiative
——————————————————————
http://www.wsupgdocs.org/news-and-media/WayneStateContentPage.aspx?nd=1293&news=515
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[14] – 8/27/2013 – Wayne State University, Detroit, Michigan, quickly realized that David H. Gorski, MD, PhD, FACS is NOT doing something wrong when he LIES about Burzynski:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/27/wayne-state-university-detroit-michigan-quickly-realized-that-david-h-gorski-md-phd-facs-is-not-doing-something-wrong-when-he-lies-about-burzynski/
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Advertisement

Critiquing: Stanislaw Burzynski in USA Today: Abuse of clinical trials and patients versus the ineffectiveness of the FDA and Texas Medical Board (Hyperactivity versus Hypernatremia, and Hannah Bradley)

I’ve made no secret of how much I dispute David H. Gorski, a la “Orac”, the “self-proclaimed” brain cancer doctor and brain cancer researcher who has been treating readers with an unproven, unapproved, NOT ordinary chemotherapeutic agent since Jesus just left Chicago, bound for Nawlins, seemingly Elaphe longissima slithering around, under, over, and past all attempts to intestate him and shut him up

Along the way, GorskGeek has become a hero to the cancer hackery industry, touted as the man who can cure incurable insomnia that science-based medicine can’t, even though his treatment, insolence, allegedly pop tarts isolated from bloopers and Uranus that normally keep insomnia in check in healthy people, are by any reasonable definition NOT ordinary chemotherapy

Indeed, they are toxic, with a number of side effects reported, the most common and dangerous of which being life-threatening hyperactivity (elevated sugar levels in the blood)

All you have to do is to type GorsGeek’s name into the search box of this blog, and you’ll find copious documentation of the abuses of patience, science, and critical trials perpetrated by “Orac” and the cult of impersonality that has evolved around him

He’s even acquired his very own film perpougendist, a credulous fellow named Bob Blaskiewicz, who has made 2 astoundingly bad hackumentaries that are nothing more than unabashed hagiographies of the brave maverick doctor curing insolence where no one else can

They’re chock full of misinformation, pseudononsense, spin, and obvious emotional manipulation, and the 2nd one, at least, was very popular

For the longest time, I’ve been hoping that major mainstream news organizations would take this story on
——————————————————————
GorskGeek claims:

“Now, thanks to Liz Szabo at USA Today, we know from her article Doctor accused of selling false hope to families [1]:

“Yet hypernatremia is one of antineoplastons’ most common side effects, known to doctors for two decades”
——————————————————————
GorskGeek, of course, does NOT care to mention the 2 hypernatremia studies that I listed in the 2nd of my 3 critiques on USA TODAY’s “hatchet job” of Burzynski [2], because, as he accuses others:

THEY DO NOT FIT HIS NARRATIVE
——————————————————————
GorskGeek continues:
——————————————————————
“showed a blood sodium level of 205 millimoles per liter, a level that is typically fatal“

“I was astounded to see that number“

“I’ve never, ever seen a sodium level that high“

“Typically, normal is typically between 135 and 145 mEq/L, with slight variations of that range depending on the lab”

“Burzynski’s excuse, which I’ve heard at various times as being due to an “improper blood draw” or as described above, is purest nonsense”

“Unless the technician spiked Josia’s sample with 3% saline or something like that, there’s no way to get the leve that high”

“Josia almost certainly died because of hypernatremia from antineoplaston therapy“

“To me, this is the biggest revelation of the story:”

“The story and identity of the child who was killed by Burzynski’s treatments“
——————————————————————
I did NOT know that GorskGeek was the
Medical Examiner for the United States Food and Drug Administration
——————————————————————
GorskGeek is mistaken, as the “purest nonsense” is his nonsensical claim:

“I’ve never, ever seen a sodium level that high“

The reason GorskGeek has:

“never, ever seen a sodium level that high”

is because he’s a “hack”, who’s more interested in churning out as many blogsplats as he can, rather than doing real “science-based medicine” research

As evidence of MY claim, I submit:
——————————————————————
9/2004 – A Non-Fatal Case of Sodium Toxicity (Hypernatremia)
——————————————————————
“6 year old boy who was taken to the hospital following a seizure attack, and lab analyses revealed a serum sodium (Na+) levels of 234 mEq/L”

“A search of the boy’s house led to the discovery of rock salt in the cabinet and a container of table salt”

“Extrapolating from the serum sodium (Na+) level, it was estimated that the child had ingested approximately 4 tablespoons of rock salt, leading to the acute toxicity“

“A literature search revealed that the serum sodium (Na+) concentration in the present report was the highest documented level of sodium in a living person“

Non-Fatal 193-209 mEq/L have been reported previously [3]
——————————————————————
We also learn that—surprise! surprise!—GorskGeek is an enormous tool

(as opposed to having “an enormous tool” His cranium is too small to have “enormous tool”)
——————————————————————
GorskGeek then hacks:
——————————————————————
“Look at him dismiss his critics, particularly former patients, many of whom, let’s recall, have terminal cancer, many of whom are dead:”

“Burzynski dismisses criticism of his work, referring to his detractors as “hooligans” and “hired assassins.””
——————————————————————
GorskGeek, you are a “hooligan”, liar, lame, loser, et al.
——————————————————————
GorskGeek proceeds:
——————————————————————
“You know, whenever I hear Burzynski fans like Eric Merola accuse skeptics of attacking cancer patients, of accusing them of horrible things”

“I think I will throw this quote right back in their faces”

“Here’s Burzynski calling his patients prostitutes, thieves, and mafia bosses, and “not the greatest people in the world,” while accusing them of wanting to “extort money from us.””
——————————————————————
GorskGeek, LAME attempt at another LIE

Burzynski did NOT CALL his patients what YOU claim he called them

Let me repeat it for YOU, because I have the sneaking suspicion that YOU are “intellectually challenged”

Burzynski SAID:

“We see patients from various walks of life”

“We see great people”

“We see crooks”

“We have prostitutes”

“We have thieves”

“We have mafia bosses”

“We have Secret Service agents”

“Many people are coming to us, OK?”

“Not all of them are the greatest people in the world”
——————————————————————
GorskGeek, just in case you did NOT learn this at the University of Michigan, there is a difference between SAYING “WE SEE” and / or “WE HAVE”, and CALLING someone something

Allow me to provide you with a great example

If I SAY that YOU are the BIGGEST POMPOUS ASS I’ve ever seen, and YOU are NOT a BIG POMPOUS ASS, then THAT is derogatory

However, if I CALL YOU the BIGGEST POMPOUS ASS that I have ever seen, because you really and truly are a BIG POMPOUS ASS; as you are, then THAT is NOT derogatory
——————————————————————
GorskGeek tries again:
——————————————————————
“Not surprisingly, he also liberally uses the Galileo gambit, but that’s not surprising, as he’s repeatedly made the hilariously arrogant and scientifically ignorant claim that he is a pioneer in genomic and personalized cancer therapy and that M.D. Anderson Cancer Center and other world-class cancer centers are “following his lead.””

“Indeed, he claimed to have invented the field 20 years ago”

“Sadly, his publication record does not support such grandiose claims“
——————————————————————
GorskGeek, how would you know ?

You proved that you weren’t smarter than a 5th grader when you could NOT find Burzynski’s 1997 Antineoplastons, oncogenes and cancer [4]
——————————————————————
“Curious as to just what the heck Burzynski was talking about here, I searched PubMed for this alleged review article”

“I couldn’t find it on PubMed“

“Perhaps Burzynski proposed this “revolutionary” new idea in a peer-reviewed article that’s not indexed in PubMed, but if he did I couldn’t find it using Google and Google Scholar“ [5]

So why should ANYONE believe that you were able to locate the rest of his publications
and review all of them?

Now THAT would be a “grandiose claim”
——————————————————————
GorskGeek was also the village “idiot savant” (minus the “savant”) who face planted:

“how Burzynski never explains which genes are targeted by antineoplastons … “ [6]

GorskGeek must have fumed for days when he found I “fact-checked” his fluff and found it false: [7-8]
——————————————————————
GorskGeek hopes to wreak havoc when he harrumphs:
——————————————————————
“For instance, experts are saying the same things I’ve been saying for a couple of years now about Burzynski’s anecdotes of “miracle cures,” such as Hannah Bradley and Laura Hymas”

“The reasons for these anecdotes include:”

“Burzynski often relies on anecdotes, which don’t tell the full story”

“Burzynski’s therapies are unproven“

“Burzynski’s patients may have been misdiagnosed“

“Burzynski’s patients may have been cured by previous therapy“

“There’s a reason why I’ve spent so much time deconstructing Burzynski anecdotes, and it’s for all of those reasons plus that anecdotes are often interpreted incorrectly by patients without medical training”

“Even doctors who are not oncologists sometimes interpret such anecdotes incorrectly to indicate that the cancer therapy chosen is the therapy that cured the patient“

“It’s not just Burzynski patient anecdotes, but it’s any cancer cure anecdote“

“That’s why clinical trials are necessary to differentiate all these confounding effects from actual effects due to the treatment”
——————————————————————
GorskiGeek displays what an abject #FAIL he is, as the question he should be asking is:

Why is the Food and Drug Administration FORCING patients to #FAIL conventional treatments; such as surgery, chemotherapy, and radiation therapy, before being allowed to utilize antineoplaston therapy ?

If the FDA was NOT doing this, then GorskGeek and the “so-called experts” would NOT have this crutch to fall back on

GorskGeek, please list all the other phase II clinical trials where the F.D.A. has done this, and please also explain what would you do if the FDA did this to YOUR clinical trials ?

I know this might require some “Grapefruits” on your part, but do try and see if you can find yours in order to pull this off, if you’re NOT the coward I think you are

And when you’re done with that, please try to explain away the case of Jessica Ressel-Doeden

GorskGeek winds up for the pitch of bullshit

He ratchets back his right arm and rockets it right into his rectum, reaches ’round and pulls out this righteousness:
——————————————————————
“Not coincidentally, Hannah Bradley had surgery, chemotherapy, and radiation, and Laura Hymas had radiation and chemotherapy”

GorskGeek, Hannah Bradley NEVER had chemotherapy, unless you are now going to claim that by “chemotherapy” you meant antineoplastons [9]

Hannah specifically mentioned:

“Chemotherapy also mentioned but not strong enough for that” [10]
——————————————————————
GorskGeek:

“Even doctors who are not oncologists sometimes interpret such anecdotes incorrectly” ?

I think you meant, even breast cancer oncologist specialists who are NOT brain cancer oncology specialists interpret incorrectly, you JackASS

In insolence

DJT
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REFERENCES:
======================================
[1] – 11/15/2013 – Stanislaw Burzynski in USA Today: Abuse of clinical trials and patients versus the ineffectiveness of the FDA and Texas Medical Board
——————————————————————
http://scienceblogs.com/insolence/2013/11/15/stanislaw-burzynski-in-usa-today-abuse-of-clinical-trials-and-patients-versus-the-ineffectiveness-of-the-fda-and-texas-medical-board/
======================================
[2] – 11/16/2013 – Critiquing: Doctor accused of selling false hope to families (USA TODAY NEWS, NATION, Liz Szabo, USA TODAY):
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/11/16/httpwww-usatoday-comstorynewsnation20131115stanislaw-burzynski-cancer-controversy2994561/
======================================
[3] – 9/2004 – A Non-Fatal Case of Sodium Toxicity
J Anal Toxicol. 2004 Sep;28(6):526-8
——————————————————————
http://www.ncbi.nlm.nih.gov/pubmed/15516309/
——————————————————————
http://www.ncbi.nlm.nih.gov/m/pubmed/15516309/
——————————————————————

Click to access 526.full.pdf

======================================
[4] – 1997 – Burzynski. S.R. Antineoplastons. oncogenes and cancer. Anti-Aging Medical Therapeutics, Vol.1. Klatz RM.
Goldman R. (Ed). Health Quest Publication 1997; Marina del Rey, CA. USA
Pg. 24
——————————————————————

Click to access burzynski_fdauntitled_promo_2012.pdf

======================================
[5] – 12/5/2012 – Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies:
——————————————————————
http://scienceblogs.com/insolence/2012/12/05/arrogance-of-ignorance-about-cancer/
======================================
[6] – 6/4/2013 – Stanislaw Burzynski versus the BBC:
——————————————————————
http://scienceblogs.com/insolence/2013/06/04/stanislaw-burzynski-versus-the-bbc/
======================================
[7] – 8/7/2013 – Critiquing: Dr. David H. “Orac” Gorski, M.D., Ph.D, L.I.A.R.:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/07/critiquing-dr-david-h-orac-gorski-m-d-ph-d-l-i-a-r/
======================================
[8] – 9/21/2013 – Critiquing: The Institute of Medicine report on cancer care: Is the system “in crisis”?:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/21/critiquing-the-institute-of-medicine-report-on-cancer-care-is-the-system-in-crisis/
======================================
[9] – 10/25/2013 – Hannah Bradley – I Feel Empowered, In Control Of My Body: Four Women On Fighting Cancer With Alternative Therapies:
——————————————————————
http://www.telegraph.co.uk/health/10383724/I-feel-empowered-in-control-of-my-body-four-women-on-fighting-cancer-with-alternative-therapies.html
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/10/25/hannah-bradley-i-feel-empowered-in-control-of-my-body-four-women-on-fighting-cancer-with-alternative-therapies-httpwww-telegraph-co-ukhealth10383724i-feel-empowered-in-control-of-my-body-fo/
======================================
[10] – 2/17/2012 – Friday – REAL LIFE – ‘I’ll try anything to beat brain cancer’
——————————————————————
http://m.gulfnews.com/i-ll-try-anything-to-beat-brain-cancer-1.981203
======================================
======================================

Critiquing: Doctor accused of selling false hope to families (USA TODAY NEWS, NATION, Liz Szabo, USA TODAY)

I gave Liz Szabo and USA TODAY the chance to act like a Spike Lee joint and “Do the Right Thing”, the same day their article came out [1]

I gave them the opportunity to prove that their article was a legitimate piece of journalism with some semblance of integrity, and NOT just akin to one of “The Skeptics™ phoned-in “rubber-stamped” yellow journalism hit pieces

Instead, it seems that Liz Szabo and / or USA TODAY decided to act as if they had rolled a Spike Lee joint

I sent an e-mail with 2 editorial corrections, and only one (correcting Lisa Merritt’s comment
link from taking the reader to the 1999 Mayo Clinic report instead of to her comments), was corrected [2]

The 2nd correction which they #FAILED to do, earns them well deserved INSOLENCE
——————————————————————
The article claims:
——————————————————————
“Burzynski, 70, calls his drugs “antineoplastons” and says he has given them to more than 8,000 patients since 1977.”
——————————————————————

——————————————————————
However, if you select the “8,000 patients” link, the referenced page does NOT indicate that at all [2]
——————————————————————

——————————————————————
It advises:
——————————————————————
“That same year, Dr. Burzynski founded his clinic in Houston where he’s since treated over 8,000 patients.” [3]
——————————————————————

——————————————————————
Nowhere does it indicate that he “treated 8,000 patients” with antineoplastons
——————————————————————

——————————————————————
The question that Liz Szabo and USA TODAY should answer, is:

1. Who is your “fact-checker”, and
2. are they smarter than a 5th grader ?
——————————————————————
In fact, Burzynski’s 2002 Securities and Exchange Commission (SEC) filing advises:

” … in 1997, his medical practice was expanded to include traditional cancer treatment options such as chemotherapy, gene targeted therapy, immunotherapy and hormonal therapy in response to FDA requirements that cancer patients utilize more traditional cancer treatment options in order to be eligible to participate in the Company’s Antineoplaston clinical trials” [4]
——————————————————————
The article continues:
——————————————————————
“Individual success stories can be misleading, said Arthur Caplan, a professor and head of the division of bioethics at NYU Langone Medical Center”
——————————————————————
The question Arthur Caplan should be asking is:

Why has the United States Food and Drug Administration required Burzynski’s clinical trial patients to fail conventional therapies; such as surgery, chemotherapy, and radiation, BEFORE they are allowed to be treated with antineoplaston therapy ?

If the F.D.A. did NOT impose these restrictions upon Burzynski’s clinical trials, then the question Arthur Caplan raises would be moot
——————————————————————
The article quotes Dr. Jan Buckner as saying:
——————————————————————
“When I hear a story that is way out of the norm, the first question I ask is,

‘OK, is the diagnosis even correct?‘ ”

“Buckner said”

“If the diagnosis wasn’t right to start with, it doesn’t matter what the treatment was.”

“Brain tumors are notoriously difficult to diagnose, Buckner says”

“When dealing with rare brain cancer, doctors may disagree about how to interpret imaging results up to 40% of the time”
——————————————————————
I wonder if Dr. Jan Buckner would agree with David Gorski; who is a BREAST cancer oncology specialist, and NOT a BRAIN cancer oncology specialist, who has the presumptiveness to speculate that 3 different medical opinions could have misdiagnosed Tori Moreno in August 1998; who was diagnosed with a very large tumor, about 3 inches in the largest diameter and located in the brain stem, which was too risky for surgery, and about which her parents were told by ALL 3, that Tori’s brain cancer was fatal and, she would die in a few days or at the most, 2-6 weeks, and that there was nothing that could be done, and was finally put on Burzynski’s antineoplaston therapy in October, when she was about 3 ½ months old, and in such condition that they were afraid that she might die at any time, David H. Gorski, M.D., Ph.D., FACS; who claims, “I do know cancer science” , has the audacity, because of his “book learnin'” has the temerity to postulate his “science-based medicine theory” that Miller’s Children at Long Beach Memorial misdiagnosed Tori Moreno’s inoperable stage 4 BSG

David Gorski has the gall to profer that City of Hope misdiagnosed Tori Moreno’s inoperable stage 4 brain stem glioma

David Gorski has the chutzpah to pontificate that Dr. Fred Epstein in New York misdiagnosed Tori Moreno’s inoperable stage IV brainstem glioma [5]
——————————————————————
The article then quotes Peter Adamson, chair of the Children’s Oncology Group:
——————————————————————
“But these therapies may have delayed benefits, taking weeks or months to shrink a tumor“

“So patients treated by Burzynski may credit him for their progress, just because he was the last doctor to treat them, says Peter Adamson, chair of the Children’s Oncology Group, an NCI-supported research network that conducts clinical trials in pediatric cancer“

“Conventional cancer treatment can also cause tumors to swell temporarily, due to inflammation“

“A patient who isn’t familiar with this phenomenon may assume her tumor is growing“

“When that swelling subsides, patients may assume it’s because of Burzynski, Adamson says”
——————————————————————
This is laughable

In support of this “phenomenon” , the article provides a link to a Canadian web-site [6]

The site posits:
——————————————————————
“RT/TMZ is now widely practiced and the standard of care for appropriately selected patients, we are learning more about the consequences of RT/TMZ”

“One phenomena, termed Pseudo-Progression (psPD)…”
——————————————————————
The problem is that this only applies to “Glioblastoma Multiforme (GBM)”, and the article provides NO proof whatsoever, that any of Burzynski’s “Glioblastoma Multiforme (GBM)” patients have taken “RT/TMZ”
——————————————————————
Additionally, the site cites the reference as:

Sanghera, Perry, Sahgal, et al., “Sunnybrook Health Sciences Odette Cancer Centre” (in press, Canadian Journal of Neuroscience)

(“In press” refers to journal articles which have been accepted for publication, but have not yet been published)

However, the journal article in question was published 1/2010, so it has NOT been “in press” for over 3 years and 7 months [7]

Get your act together, aye, Canada !
——————————————————————
The article rants and raves on and on about FDA inspection reports from as far back as 1998, but at least they did quote Richard A. Jaffe:

“In Burzynski’s defense, Jaffe notes that inspection reports represent preliminary findings”

“The FDA has not yet issued final conclusions”
——————————————————————
The article posts this ridiculous claim:
——————————————————————
“Yet the National Cancer Institute says there is no evidence that Burzynski has cured a single patient, or even helped one live longer“
——————————————————————
That’s NOT what this seems to suggest [8]
——————————————————————
Then the article quotes pediatric oncologist Peter Adamson, a professor of pediatrics and pharmacology at Children’s Hospital of Philadelphia, in what will no doubt soon be known as a “classic”:
——————————————————————
“He’s a snake oil salesman,” says pediatric oncologist Peter Adamson, a professor of pediatrics and pharmacology at Children’s Hospital of Philadelphia”
——————————————————————
All I’d like to know is, which rock did this clown crawl out from under ?

Dr. Adamson, please advise which “snake oil” has been granted Orphan Drug Designation (“ODD”) from the United States Food and Drug Administration [9], and which “snake oil” has been approved for, and used in, phase III clinical trials ? [10]
——————————————————————
Q: Is it, it the phase 2 trial is finished ?

A: “Mhmm”

Q: but they’re still accepting people ?

A: “Yeah”

Q: on more like a special ?

A: “Special basis, and, um, sometimes compassionate grounds“

A: “(compassion exception)”

A: “Uh, exceptions“

Q: That’s normal ?

A: “Yes”
“So”

A: “(Yes I guess it is a funding issue ?)”

Q: Right

A: “(Like FDA, during the 2nd phase of clinical trials they found the data to be, real, real one, and they gave him the ok to go for 3rd phase of clinical trials, but just to go through this process you would probably need $100,000)”
——————————————————————

——————————————————————
Oh, wait !!

Dr. Adamson, when you say “snake oil”, I take it you are referring to the low-dose chemotherapy that Burzynski uses ?

Dr. Adamson, do you know what a “hack” is ?
——————————————————————
In regards to the Merritt’s, the article has:
——————————————————————
“The couple say that Burzynski misled them about the type of treatment that would be offered, as well as the cost”

My questions about the Merritt’s are:

1. Where is their complaint to the Texas Medical Board ?

2. Where is their lawsuit ? Couldn’t they find an attorney to take their case pro bono ?
——————————————————————
The article continues:
——————————————————————
“Yet even Jaffe has acknowledged that the trial — now in its 17th year — was more about politics than science”

“In his 2008 memoirs, Galileo’s Lawyer, Jaffe called it “a joke.””

“”It was all an artifice, a vehicle we and the FDA created to legally give the patients Burzynski’s treatment,” Jaffe said“
——————————————————————
What Liz Szabo and her friends at USA TODAY fail to let the readers know, is that this only applied to one trial:
——————————————————————
Burzynski’s lawyer is obviously referring to the CAN-1 clinical trial mentioned in Burzynski’s 11/25/1997 Securities and Exchange Commission (SEC) filing [11]
——————————————————————
One trial that is retrospective is CAN-1 Clinical Trial
——————————————————————
CAN-1 PHASE II STUDY OF ANTINEOPLASTONS A10 AND AS2-1 IN

PATIENTS WITH REFRACTORY MALIGNANCIES

133 patients
——————————————————————
Clinical trial of patients treated by Dr. Burzynski through 2/23/1996
——————————————————————
FDA has indicated it will not accept data generated by this trial since it was not a wholly prospective one
——————————————————————
The article continues in the same vein:
——————————————————————
“In an interview, Burzynski said developing new drugs is complex and takes time”

“Yet the FDA has approved 108 cancer drugs since Burzynski began his trial”
——————————————————————
Ms. Szabo and “pals” conveniently “forgets” to educate their audience that Burzynski was using Fleming’s One-sample multiple testing procedure for phase II clinical trials [13], which requires that if the 1st 20 patients meet certain criteria, 20 additional patients are added [14]
——————————————————————
“Well, we cannot publish until the time is right” (laughs)

Yeah

“If you would like to publish the results of, of a
10 year survival, for instance”

Mmm

“Which we have
Nobody has over 10 year survival in
malignant brain tumor, but we do, and if you like to do it right, it takes time to prepare it, and that’s what we do now
What we publish so far
We publish numerous, uh, publications which were, interim reports when we are still continuing clinical trials
Now we are preparing, a number of publications for final reports“ [15]
——————————————————————
Then Fran Visco, president of the National Breast Cancer Coalition makes an outlandish statement, which is quoted in the article:
——————————————————————
“Fran Visco, president of the National Breast Cancer Coalition, describes the FDA’s tolerance of Burzynski as “outrageous.””

“They have put people at risk for a long time,” says Visco, an attorney and breast cancer survivor”

“That’s completely unacceptable”

“How can anyone look at these facts and believe that there is a real clinical trial going on … rather than just using the FDA and the clinical trial system to make money?”
——————————————————————
I have a suggestion for Ms. Visco

Take your hypocrisy and ask the American Cancer Society if they are still engaged in this kind of activity:

1. AMERICAN CANCER SOCIETY: More Interested In Accumulating Wealth Than Saving Lives [15]

2. National Cancer Institute and American Cancer Society: Criminal Indifference to Cancer Prevention and Conflicts of Interest [16]
——————————————————————
Then, ask the American Cancer Society, why is it that 10 years ago, estimated breast cancer deaths were expected to be 39,800 (15%), and this year it was 39,620 (14%), which is ONLY 180 LESS than 10 years ago ?
——————————————————————
Estimated Breast Cancer Deaths (Women)-USA
——————————————————————
2013☝39,620 (14%)
2012👇39,510 (14%)
2011👇39,520 (15%)
2010👇39,840 (15%)
2009👇40,170 (15%)
2008☝40,480 (15%)
2007👇40,460 (15%)
2006☝40,970 (15%)
2005👇40,410 (15%)
2004☝40,110 (15%)
2003☝39,800 (15%)
2002 – 39,600 (15%)
—————————————————————–
American Cancer Society Cancer Facts & Figures (2002-2013)
—————————————————————–
And then ask the American Cancer Society, why is it that 10 years ago, the estimated NEW breast cancer cases were expected to be 211,300 (32%), and this year it was 232,340 (29%), which is 21,340 MORE than it was 10 years ago ?
——————————————————————
Estimated New Breast Cancer (Women) – USA
——————————————————————
2013☝232,340 (29%)
2012👇226,870 (29%)
2011☝238,480 (30%)
2010☝207,090 (28%)
2009☝192,370 (27%)
2008☝182,460 (26%)
2007👇178,480 (26%)
2006☝212,920 (31%)
2005👇211,240 (32%)
2004☝215,900 (32%)
2003☝211,300 (32%)
2002_-_203,500 (31%)
—————————————————————–
American Cancer Society Cancer Facts & Figures (2002-2013)
——————————————————————
And after that, ask Susan G. Komen how much is spent on legal action to protect her brand, compared to how much is spent on breast cancer research and prevention ?
——————————————————————
Visco, the breast cancer advocate

“I do NOT know why it took YOU so long.”
——————————————————————
The article continues with:
——————————————————————
“Yet hypernatremia is one of antineoplastons’ most common side effects, known to doctors for two decades”
——————————————————————
Yet, “The Skeptics™” refuse to discuss:
——————————————————————
2/13/2013 – The frequency, cost, and clinical outcomes of hypernatremia in patients hospitalized to a comprehensive cancer center

Over 3 month period in 2006 re 3,446 patients, most of the hypernatremia (90 %) was acquired during hospital stay [19]

Division of Internal Medicine, UT MD Anderson Cancer Center, Houston, TX, USA

Department of General Internal Medicine, University of Texas MD Anderson Cancer Center

Division of Endocrinology, Mayo Clinic
——————————————————————
9/1999 – The changing pattern of hypernatremia in hospitalized children [20]

Department of Pediatrics, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, USA
——————————————————————
So, after all that, my question for USA TODAY is, does Liz Szabo, Michael Stravato, Jerry Mosemak or Robert Hanashiro have a
journalism degree ?

Because if any of them do, the institution they obtained it from most be so proud of this piece of “fish wrap” you produced

Thank you, USA TODAY, for censoring my 18 comments

I guess you must be (“intellectual”) cowards

At least Forbes had the GRAPEFRUITS to post some of my comments
——————————————————————
You’ve just been served, INSOLENTLY
——————————————————————
USA TODAY, GONE TOMORROW
——————————————————————

======================================
REFERENCES:
======================================
[1] – 11/15/2013 – USA TODAY NEWS, NATION
Doctor accused of selling false hope to families
Liz Szabo, USA TODAY
——————————————————————
http://www.usatoday.com/story/news/nation/2013/11/15/stanislaw-burzynski-cancer-controversy/2994561/
======================================
[2] – Mayo Clinic – 1999 – report: Lisa Merritt
——————————————————————
https://www.documentcloud.org/documents/816819-mayo-clinic-1999-report.html
======================================
[3] – 2012 – former Burzynski web-site screenshots, Pg 3 of 62;
——————————————————————

Click to access burzynski_fdauntitled_promo_2012.pdf

======================================
[4] – 4/26/2013 – Burzynski: FDA requirements that cancer patients utilize more traditional cancer treatment options in order to be eligible to participate in the Company’s Antineoplaston CLINICAL TRIALS:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/04/26/burzynski-fda-requirements-that-cancer-patients-utilize-more-traditional-cancer-treatment-options-in-order-to-be-eligible-to-participate-in-the-companys-antineoplaston-clinical-trials/
======================================
[5] – 11/14/2013 – Critiquing: Why we fight for patients (Why we fight your patience) TAM 2013, TAM2013, “The Amazing Meeting” 2013 #TAM2013 http://www.theamazingmeeting.com
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/11/14/tam-2013-tam2013-tam2013-the-amazing-meeting-2013-the-amazing-meeting-httptheamazingmeeting-com-httpwww-theamazingmeeting-com/
======================================
[6] – Phenomenon – Brain Tumour Foundation of Canada
——————————————————————
http://www.braintumour.ca/1649/ask-the-expert-psuedo-progression-gbm
======================================
[7] – Pseudoprogression following chemoradiotherapy for glioblastoma multiforme
Can J Neurol Sci. 2010 Jan;37(1):36-42
——————————————————————
http://www.ncbi.nlm.nih.gov/pubmed/20169771/
======================================
[8] – 9/19/2013 – Critiquing: National Cancer Institute (NCI) at the National Institutes of Health (NIH) CancerNet “fact sheet” :
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/19/critiquing-national-cancer-institute-nci-at-the-national-institutes-of-health-nih-cancernet/
======================================
[9] – FDA Orphan Drug Designation
——————————————————————

Click to access PressRelease_12022008_BZYR(2).pdf

======================================
[10] – 11/7/2013 – Pete Cohen chats with Sonali Patil, Ph.D., Research Scientist at The Burzynski Clinic:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/11/07/pete-cohen-chats-with-sonali-patil-ph-d-research-scientist-at-the-burzynski-clinic/
======================================
[11] – 7/9/2013 – Burzynski: The Original 72 Phase II Clinical Trials:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/07/09/burzynski-the-original-72-phase-ii-clinical-trials/
======================================
[12] – 8/21/2013 – Critiquing David H. Gorski, MD, PhD, FACS http://www.sciencebasedmedicine.org/editorial-staff/david-h-gorski-md-phd-managing-editor/
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/08/21/critiquing-david-h-gorski-md-phd-facs-www-sciencebasedmedicine-orgeditorial-staffdavid-h-gorski-md-phd-managing-editor/
======================================
[13] – 2003 – pg. 94
——————————————————————

Click to access 960.pdf

======================================
[14] – 3/1982 – Biometrics 1982; 38: 143-51
——————————————————————
http://www.ncbi.nlm.nih.gov/pubmed/7082756/
======================================
[15] – 11/9/2013 – Pete Cohen chats with Dr. Stanislaw Burzynski – Interview #2:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/11/09/pete-cohen-chats-with-dr-stanislaw-burzynski-interwiew-2/
======================================
[16] – AMERICAN CANCER SOCIETY: More Interested In Accumulating Wealth Than Saving Lives
——————————————————————

Click to access acs.pdf

======================================
[17] – 9/11/2013 – National Cancer Institute and American Cancer Society: Criminal Indifference to Cancer Prevention and Conflicts of Interest:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/09/11/national-cancer-institute-and-american-cancer-society-criminal-indifference-to-cancer-prevention-and-conflicts-of-interest/
—————————————————————
[18] – 11/13/2013 – The War on Cancer (I don’t think it means, what you think it says it means) #Winning?
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/11/13/httpcancer-orgacsgroupscontentepidemiologysurveilancedocumentsdocumentacspc-036845-pdf/
======================================
[19] – 4/24/2013 – Burzynski: HYPERNATREMIA:
——————————————————————
https://stanislawrajmundburzynski.wordpress.com/2013/04/24/burzynski-hypernatremia/
======================================
[20] – 9/1999 – Pediatrics. 1999 Sep;104(3 Pt 1):435-9
——————————————————————
http://www.ncbi.nlm.nih.gov/pubmed/10469766/
======================================

Critiquing: Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies

12/5/2012 Dr. David H. “Orac” Gorski, who claims to be a “researcher,” cooked up this gastronomically inedible MUD pie:

Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies
http://scienceblogs.com/insolence/2012/12/05/arrogance-of-ignorance-about-cancer/
and 3/11/2013 on #ScienceBasedMedicine . org:

Three myths about Stanislaw Burzynski and The Skeptics
——————————————————————
5-6/2012 – Stanislaw R. Burzynski, MD, PhD: novel cancer research and the fight to prove its worth
http://www.ncbi.nlm.nih.gov/pubmed/22875562/
Altern Ther Health Med. 2012 May-Jun;18(3):54-61.
http://www.ncbi.nlm.nih.gov/m/pubmed/22875562/
——————————————————————
Here we go again

Now here’s where we see the sheer arrogance, the sheer ignorance of the man:

Gorski quotes Dr Burzynski:

“I published the review article in a peer-reviewed journal almost 20 years ago on the principles of personalized gene-targeted therapy”

Gorski states:

“Curious as to just what the heck Burzynski was talking about here, I searched PubMed for this alleged review article”

“I couldn’t find it on PubMed”

“His only publications from the 1990s had nothing to do with cancer as a “genetic disease” or “personalized gene-targeted cancer therapy” and everything to do with antineoplastons”

“Perhaps Burzynski proposed this “revolutionary” new idea in a peer-reviewed article that’s not indexed in PubMed, but if he did I couldn’t find it using Google and Google Scholar”

“(In fact when I entered “Burznski” and “personalized gene therapy” into Google Scholar, I got the article containing the transcript of Burzynski’s interview that I’m discussing at the top of the hit list!)”

I had to choke back a rising bile in the back of my throat as I read this

I mean, seriously, such a combination of arrogance (Gorski apparently thinking that he was the kind of person who could intelligently conduct a PubMed, Google, and Google Scholar search on personalized therapy and targeting genes for cancer)

Gorski’s ignorance of the entire field of Internet searches is breathtaking!

Let’s put it this way

Gorski was in graduate school 20 years ago, and was not taught back then how to do an Internet search

Gorski fumes:

“There’s a term called “oncogene,” which describes genes that, when either mutated or too much is made, can result in cancer”

“Robert Huebner and George Todaro first coined it in 1969, and the first oncogene, src, was described in 1970, twenty years before Burzynski claims to have understood that cancer is a genetic disease”

“The first tumor suppressor gene, the retinoblastoma gene, was characterized in 1986, at least six years before Burzynski’s apparent “revelation” that cancer is a “genetic disease.””

As usual, Burzynski and Internet searching was way ahead of Gorski

One wonders if he has ever bothered to read:

Pg. 25

1987 – Liau, M.C., Szopa, M., Burzynski, B., Burzynski, S.R. Chemosurveillance: A novel concept of the natural defense mechanism against cancer. Drugs Exptl Clin Res 1987;13 (suppl 1):71-76.

OR:

Pg. 24

1997 – Burzynski. S.R. Antineoplastons. oncogenes and cancer. Anti-Aging Medical Therapeutics, Vol.1. Klatz RM.
Goldman R. (Ed). Health Quest Publication 1997; Marina del Rey, CA. USA.

Click to access burzynski_fdauntitled_promo_2012.pdf

But THAT would have required Gorski to do a search on the word “oncogene(s)”
——————————————————————

Click to access UCM326633.pdf

——————————————————————
former web-site screenshots:

Click to access burzynski_fdauntitled_promo_2012.pdf

——————————————————————
Stanislaw Rajmund Burzynski Publications:
https://stanislawrajmundburzynski.wordpress.com/2013/03/16/stanislaw-rajmund-burzynski-publications/

Burzynski: Oh, RATS!!!

After again showing how questionable the “research” of #ScienceBasedMedicine Dr. David H. “Orac” Gorski is:
https://stanislawrajmundburzynski.wordpress.com/2013/07/23/is-dr-david-h-orac-gorski-down-and-out-in-detroit-and-an-ethically-bankrupt-researcher-2/
and he is involved in the “War on Cancer,”(!!!) I decided to provide this more in-depth listing of Burzynski related scientific publications regarding animal, mice, and rat studies re: antineoplastons
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1983 – Burzynski SR, Hendry LB, Mohabbat MO, et al. Purification of structure determination, synthesis and animal toxicity studies of antineoplaston A10. In: Proceedings of the 13th International Congress of Chemotherapy. Vienna, Austria; 1983:17, PS. 12.4 11-4.
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1984 – Burzynski, S.R., Mohabbat MO, Burzynski B.
Animal toxicology studies on oral formulation of antineoplaston A10
Drugs Exptl Clin Res 1984;10:113-118
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1984 – Lee, S.S., Mohabbat, M.O., Burzynski, S.R.
Tissue culture and animal toxicity studies of antineoplaston A2
Drugs Exptl Clin Res 1984;10:607-610
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1985 – Lee, S.S., Mohabbat, M.O., Burzynski, S.R.
Tissue culture and acute animal toxicity studies of antineoplaston A2
Future Trends in Chemotherapy 1985;6:481-484
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1986 – Burzynski, S., Mohabbat. M., Lee, S.
Preclinical studies of antineoplaston AS2-1 in mice with oral administration
Drugs Exptl Clin Res 1986;132
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1986 – Burzynski, S. R., Mohabbat, M. O. , Le e, S. S. Pre clinical studies of antineoplaston AS2-1 and antineoplaston AS2-5
Drugs Exptl Clin Res 1986;12 (suppl1):11-16
http://www.ncbi.nlm.nih.gov/pubmed/3743376/
Drugs Exp Clin Res. 1986;12 Suppl 1:11-6.
http://www.ncbi.nlm.nih.gov/m/pubmed/3743376/
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1986 – Ashraf, AQ., Liau, M.C., Mohabbat, M.O., Burzynski, S.R.
Preclinical studies of antineoplaston A10 injections.
Drugs Exptl Clin Res 1986;12 (suppl 1):37-45.
http://www.ncbi.nlm.nih.gov/pubmed/3743379/
Drugs Exp Clin Res. 1986;12 Suppl 1:37-45.
http://www.ncbi.nlm.nih.gov/m/pubmed/3743379/
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1986 – Burzynski, S.R., Mohabbat M.O.
Chronic animal toxicity studies on antineoplaston A2.
Drugs Exptl Clin Res 1986;12 (suppl 1):73-75.
http://www.ncbi.nlm.nih.gov/pubmed/3743382/
Drugs Exp Clin Res. 1986;12 Suppl 1:73-5.
http://www.ncbi.nlm.nih.gov/m/pubmed/3743382/
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1987 – Lee, S.S., Mohabbat, M.O., Burzynski, SR
In vitro cancer growth inhibition and animal toxicity studies of antineoplaston A3
Drugs Exptl Clin Res 1987;13 (suppl1):13-16
http://www.ncbi.nlm.nih.gov/pubmed/3569011/
Drugs Exp Clin Res. 1987;13 Suppl 1:13-6.
http://www.ncbi.nlm.nih.gov/m/pubmed/3569011/
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1987 – Lee, S.S., Burzynski, S.R
Tissue culture and animal toxicity studies of antineoplaston A5
Drugs Exptl Clin Res 1987;13 (suppl 1):31-5.
http://www.ncbi.nlm.nih.gov/pubmed/3569013/
Drugs Exp Clin Res. 1987;13 Suppl 1:31-5.
http://www.ncbi.nlm.nih.gov/m/pubmed/3569013/
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1987 – Ashraf AQ, Liau MC, Kampalath BN, et al. Pharmacokinetic study of radioactive antineoplaston A10 following oral administration in rats. Drugs Exptl Clin Res. 1987;13(suppl 1):45-50.
http://www.ncbi.nlm.nih.gov/pubmed/3569015/
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http://www.ncbi.nlm.nih.gov/m/pubmed/3569015/
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1988 – Ashraf, AQ., Kampalath, B.N., Burzynski, S.R
Pharmacokinetic analysis of antineoplaston A10 injections following intravenous administration in rats
Adv Exptl Clin Chemother 1988;6:33-39
http://www.encognitive.com/node/2449
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7/20/1988 – Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice
http://www.ncbi.nlm.nih.gov/pubmed/3183462
Nihon Gan Chiryo Gakkai Shi. 1988 Jul.20; 23 (7):1560-5
http://www.ncbi.nlm.nih.gov/m/pubmed/3183462
23(7):1560-5 (1988)
Tsuda
N E
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1/20/1990 – A-10 Injection – The anticancer effect of antineoplaston A-10 on human breast cancer serially transplanted to athymic mice
http://www.ncbi.nlm.nih.gov/pubmed/2157780
Nihon Gan Chiryo Gakkai Shi. 1990 Jan 20;25(1):1-5
http://www.ncbi.nlm.nih.gov/m/pubmed/2157780
1st Department of Surgery, Kurume University School of Medicine
The Anticancer Effect of Antineoplaston A-10 on Human Breast Cancer Serially Transplanted to Athymic Mice, Journal of the Japan Society for Cancer Therapy 25(1):1-5 (1990)
Hashimoto K, Koga T, Shintomi Y, Tanaka M, Kakegawa T, Tsuda H, Hara H.
http://www.abstractboard.com/abstract/2157780/The-anticancer-effect-of-antineoplaston-A-10-on-human-breast-cancer-serially-transplanted-to-athymic.html
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1990 – Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines. The members of Antineoplaston Study Group
Tsuda H (Japan) et al
http://www.ncbi.nlm.nih.gov/pubmed/2175003
Kurume Med J. 1990;37(2):97-104
http://www.ncbi.nlm.nih.gov/m/pubmed/2175003
Kurume Med J 37 (2):97-104 (1990)
http://www.jstage.jst.go.jp/article/kurumemedj1954/37/2/37_2_97/_article
Kurume University School of Medicine, Japan
http://www.jstage.jst.go.jp/article/kurumemedj1954/37/2/37_2_97/_article/references
Burzynski References: 1 – 8 and 11 – 14
http://www.jstage.jst.go.jp/article/kurumemedj1954/37/2/37_2_97/_pdf
The Kurume Medical Journal
http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.1992.tb01960.x/abstract
J-STAGE, Japan Science and Technology Information Aggregator, Electronic
http://ci.nii.ac.jp/naid/130000888719
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1991 – Inhibitory effect of orally administered antineoplaston A10 on the growth curve of human breast cancer transplanted to athymic mice
http://jglobal.jst.go.jp/public/20090422/200902015871267390
J Jpn Soc Cancer Ther 26:595-601, 1991
26：3：595-601：1991 03
Kurume Univ. School of Medicine
NISHIDA H, YOSHIDA H, KUBOTA H
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5/1992 – The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis-diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma
H TSUDA, et al (Japan)
http://www.ncbi.nlm.nih.gov/pubmed/1377669
The Inhibitory Effect of the Combination of Antineoplaston A-10 Injection with a Small Dose of cis-Diamminedichloroplatinum on Cell and Tumor Growth of Human Hepatocellular Carcinoma
http://www.ncbi.nlm.nih.gov/m/pubmed/1377669
Jpn J Cancer Res. 1992 May;83(5):527-31
http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.1992.tb01960.x/abstract
Jpn. J. Cancer Res. 83, 527-531
http://onlinelibrary.wiley.com/store/10.1111/j.1349-7006.1992.tb01960.x/asset/j.1349-7006.1992.tb01960.x.pdf?v=1&t=hd97ht7z&s=3481466c7830e5f8e2bb925a698de6f8155da747
Jpn J Cancer Res. 1992 May;83 (5):527-31
http://onlinelibrary.wiley.com/store/10.1111/j.1349-7006.1992.tb01960.x/asset/j.1349-7006.1992.tb01960.x.pdf;jsessionid=4ECD3F595A3971B5AB87763862867844.d03t02?v=1&t=hbmd55gj&s=a14b626a37db3ecd558109cee30dfe26c71827763862867844
Jpn J Cancer Res 83 (5):527-31 (1992)
http://onlinelibrary.wiley.com/store/10.1111/j.1349-7006.1992.tb01960.x/asset/j.1349-7006.1992.tb01960.x.pdf?v=1&t=hkfile3i&s=2756f110cf2202084cfc90a3715d8f1f9df7774c
Department of Anesthesiology, Kurume University, School of Medicine, Fukuoka-ken
http://onlinelibrary.wiley.com/store/10.1111/j.1349-7006.1992.tb01960.x/asset/j.1349-7006.1992.tb01960.x.pdf?v=1&t=hdcl29bl&s=dd78f02b92e0f5544c136e7b897a7d65bcf5dc71&systemMessage=Wiley+Online+Library+will+be+disrupted+on+23+February+from+10%3A00-12%3A00+BST+%2805%3A00-07%3A00+EDT%29+for+essential+maintenance
Article first published online: 26 AUG 2005
DOI: 10.1111/j.1349-7006.1992.tb01960.x
Japan Journal Cancer Research
Cancer Science, Wiley Online Library
Volume 83, Issue 5, pages 527–531, May 1992
Burzynski References: 1, 4 – 7 and 9
http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.1992.tb01960.x/references
Nishida (Japan) A-10 Reference: 2
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11/15/1995 – Sodium PHENYLACETATE Induces Growth Inhibition and Bcl-2 Down-Regulation and Apoptosis in MCF7ras Cells in Vitro and in nude mice
http://cancerres.aacrjournals.org/content/55/22/5156.abstract?sid=29b3d08f-4e59-473c-a804-10c68ed99112
Cancer Res. 1995 Nov 15;55(22):5156-60.

Click to access 5156.full.pdf

Institut d’Oncologie Moléculaire et Cellulaire Humaine, Bobigny, France.
http://m.cancerres.aacrjournals.org/content/55/22/5156.full.pdf#page=1
References:
http://m.cancerres.aacrjournals.org/content/55/22/5156
1. SAMID, D., Shac, S., and Sherman, L. T. Phenylacetate: a novel nontoxic inducer of tumor cell differentiation. Cancer Res., 52: 1988-1992, 1992
http://www.naderlibrary.com/burzynski.screen3.htm
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9/2001 – Sodium PHENYLACETATE enhances the inhibitory effect of dextran derivative on breast cancer cell growth in vitro and in nude mice
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375080
Br J Cancer. 2001 September; 85(6): 917–923.
doi: 10.1054/bjoc.2001.1993
PMCID: PMC2375080
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3/2005 Effects of antineoplaston AS2-1 against post-operative lung metastasis in orthotopically implanted colon cancer in nude rat
Hideaki TSUDA
http://www.ncbi.nlm.nih.gov/pubmed/15706406
Oncol Rep. 2005 Mar; 13 (3):389-95
http://www.ncbi.nlm.nih.gov/m/pubmed/15706406
Oncol Rep 13 (3): 389-95 (2005)
http://www.spandidos-publications.com/or/13/3/389
Oncology Reports, 3/2005, Volume 13 Number 3
Pages: 389-395 Oncology Reports, Spandidos Publications
Department of Surgery, Kurume University School of Medicine, Kurume City, Fukuoka, Japan
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7 – 8/27/2007 Induction of apoptosis in human hepatocellular carcinoma cells by synthetic antineoplaston A10
http://www.ncbi.nlm.nih.gov/pubmed/17695534
Induction of Apoptosis in Human Hepatocellular Carcinoma Cells by Synthetic Antineoplaston A10
http://www.ncbi.nlm.nih.gov/m/pubmed/17695534
Anticancer Res. 2007 Jul-Aug;27(4B):2427-31
http://ar.iiarjournals.org/content/27/4B/2427.short
Anticancer Res 27(4B):2427-31 (2007)
http://ar.iiarjournals.org/content/27/4B/2427.long
Anticancer Res. 7 – 8/2007; 27(4B):2427-31

Click to access 2427.full.pdf

Anticancer Research, Vol. 27, No. 4B, 2007, pp. 2427-2431
http://www.iiar-anticancer.org/main.php?pid=3398&id=2&ch=52&gch=&volume=27&issue=4B&show=details&page=2
Anticancer Research
HighWire Press
School of Pharmaceutical Sciences, Shandong University, Jinan, Japan
International Journal of Cancer Treatment
Burzynski References: 1, 3, 5, 13 and 15
Badria (Egypt) A-10 References: 2 and 20
Wang A10 Reference: 4
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References:
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Adam L, Crépin M, Savin C, Israël L. Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice. Cancer Res. 1995 Nov 15;55(22):5156–5160.
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Shack S, Miller A, Liu L, Prasanna P, Thibault A, SAMID D. Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Clin Cancer Res. 1996 May;2(5):865–872.
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SAMID D, Shack S, Myers CE. Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate. J Clin Invest. 1993 May;91(5):2288–2295.
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SAMID D, Hudgins WR, Shack S, Liu L, Prasanna P, Myers CE. Phenylacetate and Phenylbutyrate as novel, nontoxic differentiation inducers. Adv Exp Med Biol. 1997;400A:501–505.
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SAMID D, Wells M, Greene ME, Shen W, Palmer CN, Thibault A. Peroxisome proliferator-activated receptor gamma as a novel target in cancer therapy: binding and activation by an aromatic fatty acid with clinical antitumor activity. Clin Cancer Res. 2000 Mar;6(3):933–941.
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Thibault A, Cooper MR, Figg WD, Venzon DJ, Sartor AO, Tompkins AC, Weinberger MS, Headlee DJ, McCall NA, SAMID D, et al. A phase I and pharmacokinetic study of intravenous phenylacetate
in patients with cancer. Cancer Res. 1994 Apr 1;54(7):1690–1694.
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3/2005 – Effects of antineoplaston AS2-1 against post-operative lung metastasis in orthotopically implanted colon cancer in nude rat.
http://www.ncbi.nlm.nih.gov/pubmed/15706406
Matono K, Ogata Y, Tsuda H, Araki Y, Shirouzu K.
http://www.ncbi.nlm.nih.gov/m/pubmed/15706406
Oncol Rep. 2005 Mar;13(3):389-95
http://www.spandidos-publications.com/or/13/3/389
Oncology Reports
March 2005
Volume 13 Number 3
Department of Surgery, Kurume University School of Medicine, Kurume City, Fukuoka, Japan
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PUBLICATIONS BY STANISLAW RAJMUND BURZYNSKI AND ASSOCIATES
http://www.cancermed.com
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(former web-site screenshots)

Click to access burzynski_fdauntitled_promo_2012.pdf

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Stanislaw Rajmund Burzynski Publications:

https://stanislawrajmundburzynski.wordpress.com/2013/03/16/stanislaw-rajmund-burzynski-publications/